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The Cell

A Molecular Approach

Eighth edition

Geoffrey Cooper

Publication Date - October 2018

ISBN: 9781605357072

816 pages
8.5 x 10.875 inches

In Stock

The only one-semester introduction to cell biology text built around learning objectives-and the only text to incorporate in-text and online data analysis problems


Even the most experienced instructor can find teaching cell biology daunting, and most cell biology texts are bogged down in detail or background information. Lost in all the details are the more fascinating material and contemporary advances that represent this rapidly moving field. With so much to cover, creating a classroom around active learning may be difficult or nearly impossible.

The Cell: A Molecular Approach, Eighth Edition, endeavors to address those issues with succinct writing, incorporation of current research, a test bank that encourages critical thinking, and an active learning framework. With just enough detail for a one-semester, sophomore/junior level course, the text presents fundamental concepts and current research, including chapters on Genomics and Transcriptional Regulation and Epigenetics, and new in-text boxed features on Molecular Medicine and Key Experiments. Instructors will appreciate updates to the eighth edition test bank, such as raising the Bloom's level of questions overall, and giving instructors the ability to select questions based on level.

Finally, for instructors who want to flip their classrooms or just get students more engaged, The Cell, Eighth Edition, is the only cell biology text that is accompanied by an Active Learning Guide. This chapter-by-chapter playbook shows instructors how to create a dynamic learning environment with in-class exercises, clicker questions, and links to relevant media, animations, testing, and self-quizzing, all aligned with the new in-text learning objectives, wherever appropriate. This text provides the right level of detail, student engagement, and instructor support for the modern cell biology classroom.

New to this Edition

  • Learning Objectives to focus students' attention
  • Marginal Notes to emphasize key points
  • Data Analysis Problems that challenge students to interpret experimental results
  • Active Learning Guide to facilitate the use of this approach to student engagement
  • New chapter on "Transcriptional Regulation and Epigenetics"
  • New Molecular Medicine and Key Experiment boxes, including splicing therapy of muscular dystrophy, discovery of telomerase, role of histone modifications, and mitochondrial replacement therapy


  • Ideally suited in length and complexity for sophomore- and junior-level courses at the undergraduate level.
  • Precise amount of coverage for pre-med and other students in healthcare-related majors.
  • Can be covered in a single semester. Students can master the material in its entirety, rather than sampling a small fraction from a much larger text.
  • Written in an efficient and compact style, covering a broad range of material in a direct and pedagogically approachable manner.
  • Focuses on the molecular biology of cells as a unifying theme, with topics such as developmental biology, the nervous system, the immune system, and plant biology being discussed as examples of more general principles.
  • Written by an experienced author and instructor, the unique four-part structure of this text provides comprehensive coverage from fundamental theory through to cutting-edge research.
  • An extensive range of learning features is provided to support students in identifying key points, comprehending illustrations, and learning cell biology in a broader context.
  • Through Data Analysis Problems, self-test questions, and an extensive online test bank, students are encouraged to synthesize knowledge and apply what they've learned.
  • The art program appears nearly 3-dimensional, clarifying content and allowing students to visualize movement.

About the Author(s)

Geoffrey M. Cooper is Professor Emeritus of Biology at Boston University. Receiving a Ph.D. in Biochemistry from the University of Miami in 1973, he pursued postdoctoral work with Howard Temin at the University of Wisconsin, where he developed gene transfer assays to characterize the proviral DNAs of Rous sarcoma virus and related retroviruses. He then joined the faculty of Dana-Farber Cancer Institute and Harvard Medical School in 1975, where he pioneered the discovery of oncogenes in human cancers. Since moving to Boston University in 1998, he has served as Chair of Biology and Associate Dean of the Faculty for Natural Sciences, as well as teaching undergraduate cell biology and continuing his research on the roles of oncogenes in the signaling pathways that regulate cell proliferation and programmed cell death. He has authored over 100 research papers, two textbooks on cancer and an award-winning novel, The Prize, dealing with fraud in medical research.

Table of Contents

    Part I: Fundamentals and Foundations
    Chapter 1. Introduction to Cells and Cell Research
    Chapter 2. Molecules and Membranes
    Chapter 3. Bioenergetics and Metabolism
    Chapter 4. Fundamentals of Molecular Biology
    Chapter 5. Genomics, Proteomics, and Systems Biology

    Part II: The Flow of Genetic Information
    Chapter 6. Genes and Genomes
    Chapter 7. Replication, Maintenance, and Rearrangements of Genomic DNA
    Chapter 8. RNA Synthesis and Processing
    Chapter 9. Transcriptional Regulation and Epigenetics
    Chapter 10. Protein Synthesis, Processing, and Regulation

    Part III: Cell Structure and Function
    Chapter 11. The Nucleus
    Chapter 12. Protein Sorting and Transport
    Chapter 13. Mitochondria, Chloroplasts, and Peroxisomes
    Chapter 14. The Cytoskeleton and Cell Movement
    Chapter 15. The Plasma Membrane
    Chapter 16. Cell Walls, the Extracellular Matrix, and Cell Interactions

    Part IV: Cell Regulation
    Chapter 17. Cell Signaling
    Chapter 18. The Cell Cycle
    Chapter 19. Cell Renewal and Cell Death
    Chapter 20. Cancer

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