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Process Development

Physicochemical Concepts

John H. Atherton and Keith J. Carpenter

Publication Date - 24 August 2000

ISBN: 9780198503729

96 pages


Understanding the fundamental science of the Fine Chemicals industry is necessary in the development of efficient, high-yielding and environmentally friendly processes. This is the first text to specifically address this topic by covering the physiochemical principles underpinning the subject. It outlines the strategy for obtaining the requisite data, and the chemical and chemical engineering concepts involved in process development. These include a description of pre-reaction equilibria in single and two-phase systems, factors influencing selectivity in competing reactions, mixing effects in single and two-phase reactions, the science behind workup processes and a discussion of the principles behind scale-up.


  • Describes a successful approach to process development in fine chemicals
  • Integrates chemistry and chemical engineering expertise necessary to solve process development problems
  • Provides a strategy for newcomers to the subject
  • Provides a sourcebook for teaching an integrated chemistry or chemical technology course

Table of Contents

    1. The scope of process development
    2. Strategy for process development
    3. Pre-reaction equilibria
    4. Competing reactions in homogeneous media
    5. Mixing effects in pseudo-homogeneous systems
    6. Equilibria in multiphase systems
    7. Dispersion and mass transfer in multi-phase systems
    8. Mass-transfer and reaction in two-phase systems
    9. Product isolation and workup
    10. Scale-up

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