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Organic Chemistry

Second Edition

Jonathan Clayden, Nick Greeves, and Stuart Warren

Publication Date - May 2012

ISBN: 9780199270293

1,264 pages
10.9 x 7.8 inches

In Stock

Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the student's choice of an organic chemistry text.


Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the student's choice of an organic chemistry text.

The second edition refines and refocuses Organic Chemistry to produce a text that is even more student-friendly, coherent, and logical in its presentation than before.

Like the first, the second edition is built on three principles:

An explanatory approach, through which the reader is motivated to understand the subject and not just learn the facts;

A mechanistic approach, giving the reader the power to understand compounds and reactions never previously encountered;

An evidence-based approach, setting out clearly how and why reactions happen as they do, giving extra depth to the reader's understanding.

The authors write clearly and directly, sharing with the reader their own fascination with the subject, and leading them carefully from topic to topic. Their honest and open narrative flags pitfalls and misconceptions, guiding the reader towards a complete picture of organic chemistry and its universal themes and principles.


The Companion Website (www.oup.com/uk/orc/bin/9780199270293), available to all adopters of the text, includes:
- 3D Organic Animations: Link to chemtube3d to view interactive 3D animations developed by the author
- Additional Chapters: Four chapters from the first edition that do not appear in the second
- Errata: Corrections to the book since publication
- End-of-Chapter Questions: A range of problems to accompany each chapter
- Figures in PowerPoint: Figures pre-inserted into PowerPoint for use in lectures and handouts
- Problems: Problems to accompany each chapter from the new edition of Organic Chemistry will be posted in the student area of the book's Companion Website throughout the year (April, June, and December 2012)

About the Author(s)

Jonathan Clayden is a Professor of Organic Chemistry at the University of Manchester, where he and his research group work on the construction of molecules with defined shapes - in particular those where control of conformation and limitation of flexibility is important. Jonathan was awarded a BA (Natural Sciences) from Churchill College, Cambridge before completing his PhD with Stuart Warren, also at the University of Cambridge. He has been at the University of Manchester since 1994.

Nick Greeves is the Director of Teaching and Learning in the Department of Chemistry at the University of Liverpool. Nick is a Cambridge graduate, obtaining his PhD there in 1986 for work on the stereoselective Horner-Wittig reaction with Stuart Warren. He then held a Harkness Fellowship at the University of Wisconsin-Madison and at Stanford University, California, and a Research Fellowship at Cambridge University before joining Liverpool in 1989 where he is currently a Senior Lecturer.

Stuart Warren is a former lecturer in the Department of Chemistry at the University of Cambridge and Fellow of Churchill College, Cambridge. A graduate of Trinity College, Cambridge, Stuart completed his PhD at Cambridge with Malcolm Clark before carrying out post-doctoral research at Harvard University. He became a teaching fellow at Churchill College in 1971, and remained a lecturer and researcher at Cambridge until his retirement in 2006.

Previous Publication Date(s)

August 2000

Table of Contents

    1. What Is Organic Chemistry?
    2. Organic Structures
    3. Determining Organic Structures
    4. Structure of Molecules
    5. Organic Reactions
    6. Nucleophilic Addition to the Carbonyl Group
    7. Delocalization and Conjugation
    8. Acidity, Basicity, and Pka
    9. Using Organometallic Reagents to Make C-C Bonds
    10. Nucleophilic Substitution at the Carbonyl Group
    11. Nucleophilic Substitution at C=O with Loss of Carbonyl Oxygen
    12. Equilibria, Rates, and Mechanisms
    13. 1H NMR: Proton Nuclear Magnetic Resonance
    14. Stereochemistry
    15. Nucleophilic Substitution at Saturated Carbon
    16. Conformational Analysis
    17. Elimination Reactions
    18. Review of Spectroscopic Methods
    19. Electrophilic Addition to Alkenes
    20. Formation and Reactions of Enols and Enolates
    21. Electrophilic Aromatic Substitution
    22. Conjugate Addition and Nucleophilic Aromatic Substitution
    23. Chemoselectivity and Protecting Groups
    24. Regioselectivity
    25. Alkylation of Enolates
    26. Reactions of Enolates with Carbonyl Compounds: The Aldol and Claisen Reactions
    27. Sulfur, Silicon, and Phosphorus in Organic Chemistry
    28. Retrosynthetic Analysis
    29. Aromatic Heterocycles 1: Structures and Reactions
    30. Aromatic Heterocycles 2: Synthesis
    31. Saturated Heterocycles and Stereoelectronics
    32. Stereoselectivity in Cyclic Molecules
    33. Diastereoselectivity
    34. Pericyclic Reactions 1: Cycloadditions
    35. Pericyclic Reactions 2: Sigmatropic and Electrocyclic Reactions
    36. Participation, Rearrangement, and Fragmentation
    37. Radical Reactions
    38. Synthesis and Reactions of Carbenes
    39. Determining Reaction Mechanisms
    40. Organometallic Chemistry
    41. Asymmetric Synthesis
    42. Organic Chemistry of Life
    43. Organic Chemistry Today

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