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Seventh Edition

With Dale Purves, Edited by George J. Augustine, Jennifer M. Groh, Scott A. Huettel, Anthony-Samuel LaMantia, and Leonard E. White

Available: March 2023

ISBN: 9780197616277

960 pages
Online Resource


For over 25 years, Purves Neuroscience has been the most comprehensive and clearly written neuroscience textbook on the market. This level of excellence continues in the Seventh Edition, with a balance of animal, human, and clinical studies that discuss the dynamic field of neuroscience from cellular signaling to cognitive function. New learning objectives, and more concise sections make the content even more accessible than before.

Neuroscience, Seventh Edition is intended primarily for medical, premedical, and undergraduate students. The book's length and accessible writing style make it suitable for both medical students and undergraduate neuroscience courses. Each new book includes a one-year subscription to Sylvius 4 Online, which features an interactive tutorial on human neuroanatomy as well as a magnetic resonance imaging atlas of the human brain.

New to this Edition

  • Key concepts for each chapter, with concrete learning objectives to support better understanding.
  • Expanded glossary.
  • Reconfigured coverage of sensory systems.
  • Vision is now presented as a single, integrated chapter.
  • Olfaction and Taste have been split into two chapters.
  • Extensive revisions to online study tools, including assessment questions and learning activities.


  • Provide students and instructors with an accessible and engaging account of what is known about the structure, function, and dysfunction of neural systems.
  • A guided and curated learning experience through Oxford Insight.

About the Author(s)

George Augustine is a neuroscientist known for his work on presynaptic mechanisms of neurotransmitter release and his contributions to the development of optogenetics, a tool to control neural activity using light. He is a Professor of Neuroscience and Mental Health, and the Irene Tan Liang Kheng Chari Professor in Neuroscience at Nanyang Technological University in Singapore.

Richard Mooney studies the neurobiology of hearing and communication, with special emphasis on the neural mechanisms of vocal learning, production and perception. He is the George Barth Geller Professor of Neurobiology, and Director of Graduate Studies and Faculty and Duke University.

Anthony-Samuel LaMantia researches the developmental mechanisms that build neural circuits required for distinct behaviors, investigating genetic, molecular, and cell biological analyses as well as assessment of neural circuit function and related behaviors. He is a Professor in the Department of Biological Sciences at Virgina Tech, and the Fralin Biomedical Research Institute at Virginia Tech as well as in the Department of Pediatrics at the Virginia Tech Carilion School of Medicine.

David Fitzpatrick is the CEO and Scientific Director of the Max Planck Florida Institute. His scientific contributions have earned him international recognition as a leader in systems neuroscience, with a focus on the functional organization and development of neural circuits in the cerebral cortex - the largest and most complex area of the brain, whose functions include sensory perception, motor control, and cognition.

Leonard White studies the functional architecture of the visual cortex and the role of sensory experience in development. He is at Duke University where he serves as Associate Professor in Neurology, Associate Director of the Duke Institute for Brain Science, Director of Undergraduate Studies of Psychology and Neuroscience, among other positions.

Michael Platt studies how the brain makes decisions, specifically investigating the biological mechanisms that allow people and other animals to make decisions when the environment is ambiguous. He is the James S. Riepe University Professor in the Psychology Department at the University of Pennsylvania.

Table of Contents

    Chapter 1: Studying the Nervous System
    Unit 1: Neural Signaling
    Chapter 2: Electrical Signals of Nerve Cells
    Chapter 3: Voltage-Dependent Membrane Permeability
    Chapter 4: Ion Channels and Transporters
    Chapter 5: Synaptic Transmission
    Chapter 6: Neurotransmitters and Their Receptors
    Chapter 7: Molecular Signaling within Neurons
    Chapter 8: Synaptic Plasticity
    Unit 2: Sensation and Sensory Processing
    Chaper 9: Vision
    Chapter 10: Hearing
    Chapter 11: The Vestibular System
    Chapter 12: Touch and Proprioception
    Chapter 13: Pain and Temperature
    Chapter 14: Olfaction
    Chapter 15: Taste
    Unit 3: Movement and Its Central Control
    Chapter 16: Lower Motor Neuron Circuits and Motor Control
    Chapter 17: Upper Motor Neuron Control of the Brainstem and Spinal Cord
    Chapter 18: Modulation of Movement by the Basal Ganglia
    Chapter 19: Modulation of Movememnt by the Cerebellum
    Chapter 20: Eye Movements and Sensorimotor Integration
    Chapter 21: The Visceral Motor System
    Unit 4: The Changing Brain
    Chapter 22: Early Brain Development
    Chapter 23: Construction of Neural Circuits
    Chapter 24: Experience-Dependent Plasticity in the Developing Brain
    Chapter 25: Sex Differences and Neural Circuit Development
    Chapter 26: Repair and Regeneration in the Nervous System
    Unit 5: Complex Brain Functions and Cognitive Neuroscience
    Chapter 27: Cognitive Functions and the Organization of the Cerebral Cortex
    Chapter 28: Corticol States
    Chapter 29: Attention
    Chapter 20: Memory
    Chapter 31: Speech and Language
    Chapter 32: Emotion
    Chapter 33: Thinking, Planning, and Deciding

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