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Introduction to Protein Science

Architecture, Function, and Genomics

Second Edition

Arthur M. Lesk

Publication Date - May 2010

ISBN: 9780199541300

480 pages
10.4 x 7.7 inches

In Stock

Retail Price to Students: $91.95


Designed for students in biology, biochemistry, and biomedicine, Introduction to Protein Science, Second Edition, provides a wide-ranging introduction to the contemporary study of proteins in health and disease. The text describes basic principles of protein structure and methods for studying them, illustrates the wide variety of functions that proteins have, and shows how their structures and functions are closely linked.

Introduction to Protein Science, Second Edition, relates the study of proteins to the context of modern high-throughput data streams of genomics and proteomics. It also provides a balanced treatment of the relationship between computational and experimental methods. The text is enhanced by marginal notes, exercises, problems, and "weblems" that develop students' database and computational server skills. An updated and expanded Companion Website offers resources for students and instructors.

New to this Edition

  • Coverage of new developments in the field, including high-throughput methods
  • A new chapter on enzyme kinetics
  • Extended treatments of such topics as protein evolution and the immune system
  • New pedagogical features including "key points" and "Proteins in Health and Disease" boxes
  • New end-of-chapter exercises, problems, and "weblems"

Previous Publication Date(s)

April 2004

Table of Contents

    1. Introduction: Proteins in their Biological Context
    2. Fundamentals of Protein Structure
    3. Protein Structure Determination
    4. Structural Bioinformatics
    5. Proteins as Catalysts: Enzyme Structure, Kinetics, and Mechanism
    6. Protein Interactions and Assemblies
    7. Evolution of Protein Structure and Function
    8. Protein Folding, Engineering and Design
    9. Proteomics and Systems Biology
    10. Systems Biology of Proteins
    11. Proteins in Disease