We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Find out more

E-book purchase
Choose a subscription

Downloaded copy on your device does not expire. Includes 4 years of Bookshelf Online.


Where applicable, tax will be added to the above price prior to payment.

E-book purchasing help


From Neuron to Brain

Sixth Edition

Author A. Robert Martin, David A. Brown, Mathew E. Diamond, Antonino Cattaneo, Francisco F. De-Miguel, and Foreword by John Nicholls

Publication Date - 31 December 2020

ISBN: 9781605354392

912 pages
8 1/2 x 11 inches

In Stock

A current and accessible introduction to the nervous system


From Neuron to Brain, Sixth Edition, provides a readable, up-to-date book for use in undergraduate, graduate, and medical school courses in neuroscience. As in previous editions, the emphasis is on experiments made by electrical recordings, molecular and cellular biological techniques, and behavioral studies on the nervous system, from simple reflexes to cognitive functions. Lines of research are followed from the inception of an idea to new findings being made in laboratories and clinics today.

From Neuron to Brain will be of interest to anyone--with or without a specialized background in biological sciences--who is curious about the workings of the nervous system.

New to this Edition

  • A new enhanced e-book, which includes self-study questions throughout the text based on learning objectives
  • A new Chapter 17 examines the way by which experience is acquired and stored at single synapses through local and nuclear gene expression and targeted molecular trafficking
  • A new Chapter 18 on extrasynaptic communication explains how release of substances from different regions of neurons changes the way brain circuits work
  • A new Test Bank available to adopters on the companion website

About the Author(s)

A. Robert Martin is Professor Emeritus in the Department of Physiology at the University of Colorado School of Medicine.

David A. Brown is Professor of Pharmacology in the Department of Neuroscience, Physiology, and Pharmacology at University College London.

Mathew E. Diamond is Professor of Cognitive Neuroscience at the International School for Advanced Studies in Trieste (SISSA).

Antonio Cattaneo is Professor of Physiology at the Scuola Normale Superiore in Pisa.

Francisco F. De-Miguel is Professor of Neuroscience at the Instituto de Fisiología Celular-Neurociencias of the Universidad Nacional Autónoma de Mexico (UNAM).


"From Neuron to Brain provides the best available coverage of topics for my course, in a format and level of detail that is appropriate for advanced undergraduates."--Stephen Meriney, University of Pittsburgh

"From Neuron to Brain contextualizes neuroscience through experimental findings. It allows students to explore neuroscience through the rich stories of experimental discovery--which is a much richer and more fulfilling way to be introduced to the field."--J. David Spafford, University of Waterloo

Table of Contents

    Part I: Introduction to the Nervous System

    1.Principles of Signaling and Organization
    2.Signaling in the Visual System
    3. Functional Architecture of the Visual Cortex

    Part II: Electrical Properties of Neurons and Glia

    4. Ion Channels and Signaling
    5. Structure of Ion Channels
    6. Ionic Basis of the Resting Potential
    7. Ionic Basis of the Action Potential
    8. Electrical Signaling in Neurons
    9. Ion Transport across Cell Membranes
    10. Properties and Functions of Neuroglial Cells

    Part III: Intercellular Communication

    11. Mechanisms of Direct Synaptic Transmission
    12. Indirect Mechanisms of Synaptic Transmission
    13.Release of Neurotransmitters at Synapses
    14. Neurotransmitters in the Central Nervous System
    15. Transmitter Synthesis, Storage, Transport, and Inactivation
    16. Synaptic Plasticity
    17. The Molecular and Cellular Biology of Synaptic Plasticity
    18. Mechanisms of Extrasynaptic Transmission

    Part IV: Integrative Mechanisms

    19. Autonomic Nervous System
    20. Walking, Flying, and Swimming: Cellular Mechanisms of Sensory-motor Behavior in Invertebrates
    Part V: Sensation
    21. Sensory Transduction
    22. Transduction and Transmission in the Retina
    23. Touch, Pain, and Texture Sensation
    24. Auditory and Vestibular Sensation
    25. Constructing Perception
    26. Initiation and Control of Coordinated Muscular Movements

    Part VI: Development and Regeneration of the Nervous System

    27. Development of the Nervous System
    28. Critical Periods in Sensory Systems
    29. Regeneration and Repair of Synaptic Connections after Injury

    Part VII: Conclusion

    30. Open Questions

    Appendix A. Current Flow in Electrical Circuits
    Appendix B. Metabolic Pathways for the Synthesis and Inactivation of Low-Molecular-Weight Transmitters
    Appendix C. Structures and Pathways of the Brain