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Clinical Neuroscience

Psychopathology and the Brain

Second Edition

Kelly G. Lambert and Craig H. Kinsley

Publication Date - 07 December 2010

ISBN: 9780199737055

608 pages
8 x 10 inches

In Stock


Clinical Neuroscience informs students of relevant neurobiological foundations of various mental illnesses. In this book, students will begin their journey with a tour of the brain's fundamental building blocks (neuroanatomy, neurochemistry, neurophysiology, neurodevelopment) before moving to mental health challenges and illnesses (Traumatic brain injury, Parkinson's Disease, Addiction, Schizophrenia, Obsessive-Compulsive Disorder, Depression). The final section of the book includes chapters addressing topics thought to be important for building resilience against the emergence of mental illness; these chapters cover the topics of adaptive coping strategies, hunger regulation, and the nexus between mental and immune functions. Throughout the text, the value of empirical evidence is emphasized so that meaningful progress can be made toward the identification of the most effective treatment strategies. By understanding multiple neurobiological perspectives such as neuroanatomical, behavioral, evolutionary, and neurochemical approaches currently existing in the field, students will be better prepared to conceptualize the relevant components of these mental health puzzles. Features such as opening chapter vignettes (Connections), case studies (A Case in Point) and feature boxes (Brain Matters) illuminate the course content for students as they learn about the value of translational research.

Instructor's Manual/Test Bank (9780199737079) to help instructors prepare for their lectures and homework assignments, with learning objectives, class activities and demonstrations, exercises, additional readings, and more. The test bank includes more than 800 questions organized topically and graded according to difficulty, with source information provided to link questions back to their respective sections in the text.

Companion Website to further assist the instructor, providing PowerPoint versions of the most informative images and tables in the text

New to this Edition

  • New chapter: Traumatic and Chronic Brain Injury : a chapter emphasizing more traditionally viewed neurological disorders (TBI and Parkinson's Disease)
  • Hundreds of new references
  • Color insert: To give the students a taste of the wonderful visual complexity of the brain and related issues in the text
  • Stream-lined features


  • Connections: Introduces relevant issues related to each chapter to capture the students' attention before diving into the chapter
  • Brain Matters: Interesting boxes featuring material relevant for the chapter content such as effects of humor on immune functions, animal models of depression, and ties between eating and stress
  • A case in point: The individuals living with neural challenges resulting in various mental illnesses are the true heroes of this discipline. We have searched extensively to bring some fascinating cases to this book: a little girl with half her brain removed, an actor battling the symptoms of OCD, a woman's whose artistic abilities drastically changed following a stroke that damaged her brain, a journalist held hostage for seven long years.

About the Author(s)

Kelly Lambert is Professor and Chair of Psychology at Randolph-Macon College. She is the recipient of the 2001 State Council of Higher Education in Virginia's Outstanding Faculty Award. Reports of her research have been published in journals such as Stress, Nature, and Physiology and Behavior. Her popular writing has appeared in such magazines as Scientific American Mind. She is most recently the author of Lifting Depression(Basic Books, 2008).Craig Kinsley is Professor of Neuroscience in the Department of Psychology and Center for Neuroscience at the University of Richmond. His research has been published in such journals as Brain Research Bulletin, Developmental Psychobiology, Hormones and Behavior, and Nature.

Previous Publication Date(s)

December 2010
November 2004

Table of Contents

    Part I
    Foundations of Clinical Neuroscience
    Chapter 1: Emergence of Clinical Neuroscience
    Chapter 2: Research, Treatment, and Points of View: Historical Perspectives

    Part II
    Fundamentals: Establishing Homeostasis
    Chapter 3: Macroanatomy and the Dynamic Brain
    Chapter 4: Microanatomy and Neurotransmission
    Chapter 5: Neurochemistry and Psychopharmacology
    Chapter 6: Neurodevelopment Over the Life Span

    Part III
    Disruptions of Homeostasis: Representative Clinical Disorders
    Chapter 7:Traumatic and Chronic Brain Damage
    Chapter 8: Disorders of Anxiety: Obsessive-Compulsive Disorder and Tourette's Syndrome
    Chapter 9: Mood Disorders
    Chapter 10: Schizophrenia
    Chapter 11: Drug Addiction

    Part IV
    Maintaining Homeostatis
    Chapter 12: Stress and Coping
    Chapter 13: Psychoneuroimmunology
    Chapter 14: Eating Regulation and Associated Disorders

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