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Cover

Biochemistry and Molecular Biology

Fifth Edition

Alison Snape, Despo Papachristodoulou, William H. Elliott, and Daphne C. Elliott

Publication Date - March 2014

ISBN: 9780199609499

648 pages
Paperback
10.6 x 8.1 inches

Retail Price to Students: $199.95

With exceptionally clear explanations and frequent diagrams, this is the ideal text for any bioscience student encountering biochemistry and molecular cell biology for the first time

Description

Now in its fifth edition, Biochemistry and Molecular Biology features a new author team, who have retained the much-praised clarity of previous editions, while adding a greater focus on biomedical issues and incorporating a discussion of recent developments in research.

A new chapter on the general principles of nutrition emphasizes the key principles underlying complex metabolic pathways, enabling students to appreciate an integrated view of human metabolism and nutrition. The fifth edition also features a new chapter on the control of gene expression reflects our increasing understanding of the importance and power of gene regulation.

Presented in a broader cellular context and featuring an integrated approach covering both biochemistry and molecular biology, this text is complemented by frequent diagrams. It is the perfect introduction for any student new to the subject.

New to this Edition
--A new Chapter 9, "General Principles of Nutrition," enables students to understand the key principles underlying complex metabolic pathways
--A new Chapter 26, "Control of Gene Expression" reflects the increasing emphasis on gene regulation in contemporary research
--A strengthened biomedical focus provides extra context to the processes and concepts being described
--Two new authors, Alison Snape and Despo Papachristodou, bring additional teaching and research experience in biochemistry and molecular biology to the book

New to this Edition

  • A new Chapter 9, "General Principles of Nutrition," enables students to understand the key principles underlying complex metabolic pathways
  • A new Chapter 26, "Control of Gene Expression" reflects the increasing emphasis on gene regulation in contemporary research
  • A strengthened biomedical focus provides extra context to the processes and concepts being described
  • Two new authors, Alison Snape and Despo Papachristodou, bring additional teaching and research experience in biochemistry and molecular biology to the book

Features

  • An accessible writing style makes the text ideal for students encountering the subject for the first time
  • Broad coverage takes students from the basic building blocks of life through to metabolism, genetics, cell signalling, and the immune system
  • Clear sub-headings and extensive cross-referencing make the text easy to navigate and allows chapters to be used in any order
  • A user-friendly design and layout is complemented by frequent diagrams to illustrate important concepts
  • A student resource website is available online at http://global.oup.com/uk/orc/biosciences/molbiol/snape biochemistry5e/

About the Author(s)

Alison Snape is Programme Director for the BSc in Biomedical Science and Lecturer in Biochemistry at King's College London. Her research interests include gene expression and differentiation in early embryonic development.

Despo Papachristodoulou is Senior Lecturer in Biochemistry and Head of Preclinical Medicine at King's College London School of Medicine. Her research interests include diabetes and diabetic complications, insulin metabolism, intermediary metabolism, nutrition, medical education, and curriculum development.

The late William H. Elliott was Head of the Biochemistry department at the University of Adelaide.

Prior to her retirement, Daphne C. Elliott was a senior lecturer at Flinders University. She is one of the first Australian women to win the prestigious Commonwealth Scholarship.

Previous Publication Date(s)

March 2014
March 2009
February 2005

Table of Contents

    Part 1: Basic concepts of life
    1. The basic molecular themes of life
    2. Cells and viruses
    3. Energy considerations in biochemistry
    Part 2: Structure and function of proteins and membranes
    4. The structure of proteins
    5. Methods in protein investigation
    6. Enzymes
    7. The cell membrane and membrane proteins
    8. Muscle contraction, the cytoskeleton, and molecular motors
    Part 3: Metabolism and Nutrition
    9. General principles of nutrition
    10. Food digestion, absorption, and distribution to the tissues
    11. Mechanisms of transport, storage, and mobilization of dietary components
    12. Principles of energy release from food
    13. Glycolysis, the TCA cycle, and the electron transport system
    14. Energy release from fat
    15. An alternative pathway of glucose oxidation. The pentose phosphate pathway
    16. Synthesis of glucose (gluconeogenesis)
    17. Synthesis of fat and related compounds
    18. Nitrogen metabolism: amino acid metabolism
    19. Nitrogen metabolism: nucleotide metabolism
    20. Mechanisms of metabolic control and their applications to metabolic integration
    21. Raising electrons of water back up the energy scale -- photosynthesis
    Part 4: Information storage and utilization
    22. The genome
    23. DNA synthesis, repair, and recombination
    24. Gene transcription
    25. Protein synthesis and controlled protein breakdown
    26. Control of gene expression
    27. Protein sorting and delivery
    28. Manipulating DNA and genes
    Part 5: Cells and tissues
    29. Cell signalling
    30. The cell cycle, cell division, and cell death
    31. Cancer
    Part 6: Protective mechanisms against disease
    32. Special topics: blood clotting, xenobiotic metabolism, reactive oxygen species
    33. The immune system

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