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The Molecular Basis of Life

Seventh Edition

James R. McKee and Trudy McKee

Publication Date - July 2019

ISBN: 9780190847609

944 pages
8-1/2 x 11 inches

In Stock

Retail Price to Students: $229.99

In One Semester. The Coverage You Want. The Relevance Your Students Need. The Resources You Must Have.


Biochemistry: The Molecular Basis of Life is an intermediate, one-semester text written for students on degree pathways in Chemistry, Biology, and other Health and Life Sciences. Designed for students who need a solid introduction to biochemistry, but are not specializing in the subject, the text focuses on essential biochemical principles that underpin the modern life sciences, and offers the most balanced coverage of chemistry and biology of any text on the market. The text equips students with a complete view of the living state, emphasizes problem solving, and applies biochemical principles to the fields of Health, Agriculture, Engineering, and Forensics, to show students the relevance of their learning. McKee and McKee is respected for its balance of biology and chemistry, consistently placing biochemical principles into the context of the physiology of the cell and biomedical applications.

New to this Edition

  • New and Updated Applications: Includes two new "Biochemistry in Perspective" essays on Alzheimer's disease and the Ebola virus, and a new "Biochemistry in the Lab" essay, which introduces the genome-editing tool CRISPR
  • New, expanded, and updated coverage on current and relevant topics, including non-coding RNA and gene expression, carcinogenesis, diabetes, the atherosclerotic process, proteomics, protein analysis, and bioinformatics
  • Expanded Problem-Solving Program: Offers hundreds of new end-of-chapter questions organized by section number and problem type (multiple-choice, fill-in-the-blank, short-answer, and critical thinking), and an all-new set of questions designed to help students preparing for the MCAT exam
  • Brand-New Illustrations: With thirty-four new figures, the seventh edition incorporates a superior and expanded art program designed to help students develop a strong visual grasp of biochemical processes. Many figures have been enhanced for vivid, clear, and consistent presentation.
  • Improvements to the general and organic chemistry primer
  • New visual chapter summaries

About the Author(s)

James R. McKee is Professor of Chemistry at the University of the Sciences, Philadelphia.

Trudy McKee is a biochemist who has taught Biochemistry at Thomas Jefferson University, Rosemont College, Immaculata College, and the University of the Sciences.


"McKee's Biochemistry is by far the best available textbook on the market for a one semester undergraduate Biochemistry course. It is very reader-friendly and has a better flow than most Biochemistry textbooks. This textbook goes beyond being a good reference book for students. Several features like key concepts, medical correlations, chapter summaries, 'Biochemistry in Perspective,' and end-of-chapter problems help guide learning and provide valuable study materials."--Niina Ronkainen, Benedictine University

"McKee's Biochemistry is an excellent, one-semester biochemistry text that covers the major topics to an appropriate depth for health professions students. It is concise yet provides enough details to lay a solid biochemistry foundation."--Joe Deweese, Lipscomb University

"The amount of material covered and the depth of the coverage is very good for a one-semester biochemistry course. The clinical examples to start each chapter are very nice and a good way to interest students in the material. The writing is at a level that will be helpful to students."--Michael Gunther, West Virginia University

Table of Contents

    Chapter Opening Vignettes
    Biochemistry in Perspective Essays
    Biochemistry in the Lab Boxes
    General and Organic Chemistry Review Primer

    1. Biochemistry: An Introduction
    2. Living Cells
    3. Water: The Matrix of Life
    4. Energy
    5. Amino Acids, Peptides, and Proteins
    6. Enzymes
    7. Carbohydrates
    8. Carbohydrate Metabolism
    9. Aerobic Metabolism I: The Citric Acid Cycle
    10. Aerobic Metabolism II: Electron Transport and Oxidative Phosphorylation
    11. Lipids and Membranes
    12. Lipid Metabolism
    13. Photosynthesis
    14. Nitrogen Metabolism I: Synthesis
    15. Nitrogen Metabolism II: Degradation
    16. Integration of Metabolism
    17. Nucleic Acids
    18. Genetic Information
    19. Protein Synthesis

    Appendix: Solutions

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