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Cover

An Introduction to Medicinal Chemistry

Seventh Edition

Graham L. Patrick

Publication Date - 15 June 2023

ISBN: 9780198866664

960 pages
Paperback
10.9 x 8.6 inches

In Stock

Description

An Introduction to Medicinal Chemistry, Seventh Edition, offers a complete and accessible approach to this multidisciplinary field. Its student-friendly writing style makes this text an ideal tool for those coming to the subject for first time, but also for students looking to deepen their understanding. From principles to practice, accompanied by examples and case studies emerging from current biomedical research, this book will equip students with a robust understanding of medicinal chemistry, and to prepare them for future success.

New to this Edition

  • Newly added high-level Multiple-Choice Questions to support self-directed learning and challenge the understanding of the processes and concepts covered
  • Updated and new Protein Data Bank Exercises available online.
  • New and updated assignments to help students develop their data analysis and problem-solving skills
  • Full-colour images throughout the new edition enhance the student experience by helping them to better visualise the concepts presented.
  • Also available as an e-book with functionality, navigation features, and links that offer extra learning support.

Features

  • The author's renowned clarity of writing and the book's logical structure help to address the challenges of teaching and studying Medicinal Chemistry.
  • New chapters on Protein Kinase and Antibodies provide insightful, up-to-date coverage of some of the most significant topics in the subject today
  • The pedagogical features enhance student engagement, which supports better knowledge retention, and a more confident application of concepts and ideas to unfamiliar problems.
  • Boxes and case studies support a real-life applied approach that helps lecturers to show how theoretical content relates to the practical reality of medicinal chemistry.
  • Full-colour images throughout the new edition enhance the student experience by helping them to better visualise the concepts presented.
  • New and updated exercises, questions, and activities throughout the book and online help students to hone their problem-solving skills.
  • Also available as an e-book with functionality, navigation features, and links that offer extra learning support.

About the Author(s)

Graham Patrick, Associate Lecturer, University of the West of Scotland

Graham Patrick, Lecturer in Organic Chemistry and Medicinal Chemistry, University of the West of Scotland.

Dr Graham Patrick gained his BSc Honours at Glasgow University, winning the McKay-Smith Prize for Chemistry. He completed his PhD with Professor Kirby and Professor Robins studying the biosynthesis of gliotoxin and related fungal metabolites. Following this, he worked in the pharmaceutical industry as a research chemist and radiochemist on a variety of projects that included topic areas such as opioids, antibacterial agents and antidepressants. His academic career has included positions at Leeds and Strathclyde Universities as well as the Australian National University. He joined the University of Paisley (now the University of the West of Scotland) in 1990, teaching medicinal chemistry and drug design. Currently, he is an Associate Lecturer with the Open University, an author of scientific textbooks and fiction, and an historical archivist

Table of Contents

    Chapter 1 Drugs and Drug Targets
    Chapter 2 Protein Structure and Function
    Chapter 3 Enzymes: Structure and Function
    Chapter 4 Receptors: Structure and Function
    Chapter 5 Receptors and Signal Transduction
    Chapter 6 Nucleic Acids: Structure and Function
    Chapter 7 Enzymes as Drug Targets
    Chapter 8 Receptors as Drug Targets
    Chapter 9 Nucleic Acids as Drug Targets
    Chapter 10 Miscellaneous Drug Targets
    Chapter 11 Pharmacokinetics and Related Topics Chapter Case Study 1 Statins
    Chapter 12 Drug Discovery: Finding a Lead
    Chapter 13 Drug Design: Optimizing Target Interactions
    Chapter 14 Drug Design: Optimizing Access to the Target
    Chapter 15 Getting the Drug to Market

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