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Transfusion and Transplantation Science

Second Edition

Edited by Neil Avent

April 2018

ISBN: 9780198735731

368 pages

In Stock

Fundamentals of Biomedical Science

Price: £29.99

The only text to successfully bring together the theory and practice of transfusion and transplantation in an accessible way for undergraduate biomedical science students.



Synthesizes the wide-ranging concepts essential to transfusion and transplantation science and presents them within the practical framework of the hospital banking and transplantation centre, providing you with the knowledge and skills to specialize in this discipline.

  • A blend of science theory and biomedical science practice make this series ideal for those seeking both the knowledge and skills to become proficient Biomedical Scientists
  • Case studies and other examples enrich the text, firmly rooting it in the context of clinical and biomedical practice
  • Self-test and discussion questions, with answers provided online, encourage students to analyze the text and develop their problem solving skills
  • The book is augmented by an Online Resource Centre, which includes video interviews with practicing biomedical scientists and 'in the lab' footage showing biomedical science in practice

New to this edition

  • A completely revised chapter on all human blood group systems, their antigens, genes, and function in the red cell, and including new developments in blood group genotyping.
  • A new chapter on haemolytic disease of the newborn and fetus, including prenatal diagnosis, current clinical management, screening of D-negative mothers, and non-invasive prenatal blood grouping.
  • A revised chapter on solid organ transplantation , including the clinical management of transplants, major rejection episodes, the management of transplantation by immunosuppression, and the potential of xenotransplantation to alleviate the shortfall of human organs.
  • All remaining chapters have been revised and updated.
  • Case studies have been extended to help foster an understanding of the diagnostic process, taking the reader through each clinical case from initial presentation to the interpretation of results.

About the Author(s)

Edited by Neil Avent, Professor of Molecular Diagnostics and Transfusion Medicine, School of Biomedical & Healthcare Sciences, Plymouth University

Professor Neil Avent is Professor of Molecular Diagnostics and Transfusion Medicine at the School of Biomedical & Healthcare Sciences of Plymouth University. He has taught transfusion and transplantation to undergraduates since 1999 and to biomedical scientists at Masters levels.

Table of Contents

    1:Introduction to Basic Immunology and Techniques, Neil D. Avent
    2:Human Blood Group Antigens, Neil D. Avent
    3:Haemolytic Disease of the Fetus and Newborn, Neil D. Avent
    4:Clinical Use of Blood Components, Lionel Mohabir
    5:Microbiological Testing of Blood Donations, Catherine Hyland, John Barbara, and Lionel Mohabir
    6:Human Platelet Antigens (HPA) and Human Neutrophil Antigens (HNA) and their Clinical Significance, Geoff Lucas
    7:Compatibility Testing and Adverse Effects, Malcolm Needs
    8:Immune Mediated Red Cell Destruction, Malcolm Needs
    9:Human Leucocyte Antigens (HLA) and their Clinical Significance, Neil D. Avent
    10:Haematopoietic Stem Cell Transplantation and Stem Cell Plasticity, Ruth Morse and Saeed Kabrah
    11:Tissue Banking, Richard Lomas, Neil D. Avent, and Vehid Salih
    12:Quality Issues, Joan Jones


Review from previous edition Excellent teaching material for those studying Biomedical Science. - Dr Stephen F. Hughes, University of Chester

There is a clear focus on practical application of the theory in the transfusion lab. - Dr Christine Shirras, Lancaster University

The main strength is the Biomedical Science perspective. The emphasis is on transfusion practice within the laboratory: the biochemistry backs up the practical applications, not the other way round as biochemistry texts often do. - Trish Procter, Keele University

Additional Resources

The Online Resource Centre to accompany Transfusion and Transplantation Science features:

For registered adopters of the book:
· Figures from the book, available to download

For students:
· Answers to questions in the book
· An interactive digital microscope, encouraging the exploration of tissue samples
· Videos including interviews with practicing biomedical scientists and 'in the lab' footage showing biomedical science in practice

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