Pharmaceutical Chemistry

Description

Pharmaceutical Chemistry provides a wide-ranging overview of organic chemistry as applied to the study and practice of pharmacy. Drugs are simply chemicals, so to fully understand their manufacture, formulation, and the way they work in our bodies, a knowledge of organic compounds and their reactions is essential.

• Supports integrated pharmacy education, so that students are learning in a professionally relevant context from day one
• Focuses on the fundamental ideas that first year students need to fully grasp before progressing with more advanced study
• Material clearly demonstrates connections between scientific concepts and principles and how they are applied to pharmacy
• Written by subject experts and edited by academics with a wealth of teaching experience
• Available for students and institutions to purchase in a variety of formats, and is supported by online resources.

New to this edition

• Four new chapters examine biologically important molecules, both their roles in the body and their use as drugs: nucleic acids, proteins, carbohydrates and lipids
• A new chapter explores the role of chemistry in the absorption, distribution, metabolism and excretion (ADME) of drugs
• An expanded section discusses the use of biotechnology for the production of drugs

About the Author(s)

Chris Rostron, Honorary Research Fellow, Liverpool John Moores, and Jill Barber, Reader, The University of Manchester

Dr Chris Rostron (editor), graduated in Pharmacy from Manchester University and completed a PhD in Medicinal Chemistry at Aston University. He gained Chartered Chemist status in 1975. He is now an Honorary Research Fellow in the School of Pharmacy and Biomolecular Sciences at Liverpool John Moores University. He was a member of the Academic Pharmacy Group Committee of the Royal Pharmaceutical Society of Great Britain and chairman for 5 years. He was chairman of the Academic Pharmacy Forum and deputy chair of the Education Expert Advisory Panel of the Royal Pharmaceutical Society. He has been an external examiner in Medicinal Chemistry at a number of Schools of Pharmacy both in the UK and abroad. In 2008, he was awarded honorary membership of the Royal Pharmaceutical Society of Great Britain for services to Pharmacy education.

Dr Jill Barber (editor), studied Natural Sciences at the University of Cambridge and completed a PhD in Bio-organic Chemistry at the same university in 1980. She then spent five years in some of the oldest universities in Europe, learning Biochemistry, German and Renaissance Music. She settled in Manchester in 1986, with a permanent position in the School of Pharmacy and Pharmaceutical Sciences, where her research focuses on drugs that inhibit protein synthesis and she teaches chemotherapy and its underlying chemistry and biochemistry. She has published several teaching-related research papers about the factors influencing student success.

Table of Contents

1:The importance of pharmaceutical chemistry
2:Organic structure and bonding
3:Stereochemistry and drug action
4:Properties of aliphatic hydrocarbons
5:Alcohols, phenols, ethers, organic halogen compounds and amines
6:The carbonyl group and its chemistry
7:Introduction to aromatic chemistry
8:Inorganic chemistry in pharmacy
9:Nucleic acids
10:Proteins and enzymes
11:Carbohydrates and carbohydrate metabolism
12:Lipids
13:Origins of drug molecules
14:Absorption, distribution, metabolism and excretion

Reviews

"The go-to reference for our foundation year students and new MPharm students! [...] Being written in such an integrated manner, it fits very nicely to support the integrated delivery of pharmacy as favoured by the GPhC and, perhaps more importantly, it delivers a much richer experience to the reader. " - Dr Mark Hewitt, University of Wolverhampton

"The preface with the learning objectives is a very good innovation as it sets in context what the reader would be expected to encounter as they negotiate the narrative. The guides that relate back to earlier chapters are helpful, reminding the reader that the topics should not necessarily be considered in isolation. The readers' understanding can be gauged in the self-check sections and encapsulating key points in the boxes is also very helpful. " - Dr Don Green, London Metropolitan University

Additional Resources

Digital formats and resources

Pharmaceutical Chemistry is supported by online resources and is available for students and institutions to purchase in a variety of formats.

The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks

The online resources include:

For students:
- Self-assessment questions to help the reader to check and reinforce understanding of the material introduced in each chapter
- Bonus material to accompany chapters 3, 7 and 11
- Answers to self-check questions from the book

For registered adopters of the book:
- Figures from the book, available to download.