Modern Thermodynamics for Chemists and Biochemists

Description

Thermodynamics is fundamental to university curricula in chemistry, physics, engineering and many life sciences. It is also notoriously difficult for students to understand, learn and apply. This book explains the fundamental concepts with great clarity, and shows how they can be applied to a variety of chemical and life science contexts.

• Clarity of explanation of many difficult concepts
• All mathematics fully and accessibly presented
• Vivid, easy-to-read writing style
• Many fresh examples
• Covers latest applications of thermodynamics for biochemists, biochemical engineers and pharmacists
• Includes comprehensive glossary

About the Author(s)

Dennis Sherwood, Managing Director, The Silver Bullet Machine Manufacturing Company LTD, and Paul Dalby, Professor of Biochemical Engineering and Biotechnology, University College London

Dennis Sherwood is Managing Director of The Silver Bullet Machine Manufacturing Company Ltd. Dennis coauthored Crystals, X-rays and Proteins (Oxford University Press, 2010) and is the author of Introductory Chemical Thermodynamics (Longman, 1971). He earned his PhD in Biology at University of California at San Diego.

Paul Dalby is Professor of Biochemical Engineering and Biotechnology at University College London, and Co-Director of the EPSRC Centre for Innovative Manufacturing in Emergent Macromolecular Therapies. Paul's research combines protein engineering and formulation, with biophysical characterisation, to understand the factors that influence protein stability. This informs protein engineering and formulation designs that can improve therapeutic protein manufacturing and delivery to patients. Paul earned his PhD in Chemistry from the University of Cambridge.

Table of Contents

Part 1 - Fundamentals
1:Systems and states
2:Work and energy
3:Temperature and heat
4:Thermodynamics and mathematics
Part 2 - The Three Laws
5:The First Law of Thermodynamics
6:Enthalpy and thermochemistry
7:Ideal gas processes - and some non-ideal ones too
8:Spontaneous changes
9:The Second Law of Thermodynamics
10:Clausius, Kelvin, Planck, Carathéodory and Carnot
11:Order, information and time
12:The Third Law of Thermodynamics
Part 3 - Free energy, spontaneity and equilibrium
13:Free energy
14:Chemical equilibrium and chemical kinetics
Part 4 - Chemical applications
15:Phase equilibria
16:Reactions in solution
17:Acids, bases, and buffer solutions
18:Boiling points and melting points
19:Mixing and osmosis
20:Electrochemistry
21:Mathematical round-up
22:From ideal to real
Part 5 - Biochemical applications
23:The biochemical standard state
24:The bioenergetics of living cells
25:Macromolecular conformations and interactions
26:Thermodynamics today - and tomorrow

Reviews

"What makes this book different, and special, is the clarity of the text. The writing style is fluid, natural and lucid, and everything is explained in a logical and transparent manner." - , , BookAuthority

"Thermodynamics is one of the few scientific disciplines which has, and continues to have, a deep impact across many areas in sciences and engineering. It is often regarded difficult to understand and few books have been written with the clarity that Sherwood and Dalby have done. They welcome the reader with an intuitive narrative and excellent use of everyday examples. Although the field was established more than three centuries ago, it continues to drive todays innovations in, for example, rechargeable batteries, drug development and diagnostics. This book will set new standards for the field." - Professor Nikolaj Gadegaard, School of Engineering, University of Glasgow

"Remembering my own time as an undergraduate, thermodynamics was always a struggle, concepts seeming to get lost in a sea of equations. Yet at its heart, all of thermodynamics follows from a few beautiful ideas from which emerge the whole field. It is these concepts that this book articulates to the benefit of us students at all career stages!" - Professor Miles Padgett, Kelvin Chair of Natural Philosophy, University of Glasgow

"This is an excellent book, covering many of the essential elements of a topic which is of central importance to scientists and engineers. The book is highly readable, and accessible, making it suitable for undergraduate students, and yet contains sufficient advanced material to make it of interest to postgraduates, and experienced researchers." - Professor Omar Matar, Department of Chemical Engineering, Imperial College London

"Proper understanding of classical thermodynamics is a daunting challenge for teacher and student alike. This book nicely navigates the transition from elegant concepts to modern applications, particularly in the context of biochemical systems." - Professor Alan Cooper, School of Chemistry, University of Glasgow

"This book's structure of unambiguous explanation of the fundamentals, followed by the application of those principles to chemical and biochemical settings, allows the reader to see thermodynamics as a tool to understand and design biological systems, rather than as an end in itself." - Professor Daniel Bracewell, Department of Biochemical Engineering, University College London