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Introduction to Protein Science

Architecture, Function, and Genomics

Third Edition

Arthur Lesk

January 2016

ISBN: 9780198716846

488 pages
Paperback
265x195mm

In Stock

Price: £47.99

The only text to provide a wide-ranging perspective on the study of protein structure and function in the context of bioinformatics and genomics, with opportunities for problem solving throughout.

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Description

Written by a leading author in the field, Introduction to Protein Science provides a wide-ranging perspective on the study of protein structure and function in the context of bioinformatics and genomics. Opportunities for active learning are provided both in the text and online, enabling students to develop their problem solving skills.

  • Protein science is presented in the context of bioinformatics and genomics by a leading author in the field
  • Students are encouraged to develop their problem solving skills through provision of problems, exercises, and web-based problems
  • Suitable for students from a range of backgrounds, as little prior knowledge of the subject area is assumed

New to this edition

  • The artwork has been refreshed throughout, with new online rotating structures more clearly depicting complex three dimensional structures
  • Increased coverage of areas at the forefront of research, such as the regulation of protein activity and molecular dynamics
  • Further emphasis on the applied aspects of protein science to enable students to see why protein science is such a hot topic in research
  • Web-based problems are now online for quicker access to web links

About the Author(s)

Arthur Lesk, The Pennsylvania State University

Arthur M. Lesk is Professor of Biochemistry and Molecular Biology at The Pennsylvania State University. He is the author of the highly successful Introduction to Bioinformatics, and Introduction to Genomics, both published by Oxford University Press.

Table of Contents

    1:Introduction
    2:Protein structure
    3:Protein structure determination
    4:Bioinformatics of protein sequence and structure
    5:Proteins as catalysts: enzyme structure, kinetics, and mechanism
    6:Proteins with partners
    7:Evolution of protein structure and function
    8:Protein folding and design
    9:Proteomics and systems biology

Reviews

"The third edition of Introduction to Protein Science continues to be a brilliant superior textbook for undergraduate and new postgraduate students in biology and chemistry." - Acta Crystallographica Section D, Volume D72, Part 12 (pp. 1227-1309, 1 December 2016)

"It would be difficult to express the qualities of this book better than Doolittle (2005) in his review of the first edition: How can a book with only seven chapters cover so many topics so thoroughly and so well? For one thing, Lesk is a gifted writer with a knack for making complex material eminently understandable. For another, he has managed an adroit balancing of the carefully crafted main text with dozens of well-situated "boxes" and "case studies", each of which provides intriguing connections to the subject at hand." - Acta Crystallographica Section D, Volume D72, Part 12 (pp. 1227-1309, 1 December 2016)

"This new edition is, above all, an excellent update of the previous one." - Acta Crystallographica Section D, Volume D72, Part 12 (pp. 1227-1309, 1 December 2016)

Additional Resources

The Online Resource Centre to accompany Introduction to Protein Science features:

For students:
·Hints to end-of-chapter problems.
·Rotating structures from the book to help students visualize proteins in 3D.
·Web-based problems for students to complete online.
·Links to useful website, to aid further research into the subject

For registered adopters:
·Figures from the book in electronic format, ready to download
·Answers to end-of-chapter exercises

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