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Introduction to Genomics

Third Edition

Arthur Lesk

March 2017

ISBN: 9780198754831

544 pages

In Stock

Price: £47.99

The most current, complete and compellingly written textbook for those studying Genomics for the first time.



The most up-to-date and complete textbook for first time genomics students, Introduction to Genomics offers a fascinating insight into how organisms differ or match; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing.

  • This fully updated and restructured new edition, which includes two new chapters, takes account of new developments and technologies, presenting a logical and coherent overview of genome science today.
  • The author's widely-praised writing style leads the reader through a conceptually challenging subject in a clear, lucid way, building confidence in, and enthusiasm for, the subject at the outset.
  • Broad and fascinating range of 'real world' examples, which are also relevant across genetics modules more widely.
  • New 'looking forward' feature making the links between each chapter explicit and helping students connect seemingly different topics.
  • Extensive learning tools throughout - most notably the exercises, problems and online weblems accompanying each chapter - encourage and support self-directed learning, helping the student to master the subject.
  • An Online Resource Centre featuring an extensive range of resources for both lecturers and students, enhancing the value of the book as a teaching and learning tool.

New to this edition

  • Two new chapters focused on human genomics, health and disease with particular emphasis on the concrete outcomes of the human genome project and advances in cancer genomics.
  • A comprehensive introductory chapter that 'sets the scene' for new students of genomics.
  • A new feature that links the topics covered in each chapter.
  • New and updated chapter exercises, problems and weblems.
  • Highlighted key terms are collated in a glossary at the end of the book.

About the Author(s)

Arthur Lesk, Professor of Biochemistry and Molecular Biology, The Pennsylvania State University

Arthur M. Lesk is Professor of Biochemistry and Molecular Biology at The Pennsylvania State University, USA.

Table of Contents

    2:The Human Genome Project
    3:Mapping, Sequencing, Annotation, and Databases
    4:Evolution and Genomic Change
    5:Genomes of Prokaryotes and Viruses
    6:Genomes of Eukaryotes
    7:Comparative Genomics
    8:The Impact of Genomics on Human Health and Disease
    9:Genomics and Anthropology
    13:Systems Biology


Review from previous edition This book is great for introducing the field of genomics, providing the basic concepts underpinning the field, including cutting edge techniques, along with examples of its application. - Dr Emma Laing, University of Surrey

The writing is eloquent and engages the curious reader with a wide range of background stories. The practical applications are always highlighted. Rather than a text book studied to pass an exam, this book is a pleasure to read. - Dr Richard Bingham, University of Huddersfield

It's the best textbook that I have reviewed for upper level undergraduates. It has good basic coverage of human aspects, databases, and comparative genomics. I like the questions and problems at the end of the chapters. - Professor Michael Shiaris, University of Massachusetts Boston

Additional Resources

The Online Resource Centre accompanying Introduction to Genomics features:

For students:
- Extensive and imaginative weblems (web-based problems) for each chapter designed to give you practice with the tools required for further study and research in the field
- Hints and answers to end-of-chapter problems and exercises support your self-directed learning
- Guided tour of websites and major archival databanks in genomics offer a wealth of resources to springboard your own research
- Journal club: links to related research articles on topics covered in the book are paired with engaging questions to improve your interpretation of the primary literature
- Rotating figures allow you to visualize complex structures

For registered adopters:
- Downloadable figures from the book.

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