Infection & Immunity

Description

Gives a perfectly balanced overview of the field, describing the key infectious agents our bodies encounter and how our immune system responds to them. It also explains how diseases are spread and what measures we can take to control this spread, from vaccination to increasing public awareness.

• The only book to effectively weave mechanisms of infection and immunity together at an introductory level.
• Clinical references and case studies, combined with substantial coverage of diseases, makes this book valuable to both biomedical and medical students.
• Stunning full-colour artwork brings the subject to life, complementing the text.
• An Online Resource Centre features additional resources for lecturers and students, enhancing the text's educational value.

New to this edition

• Two new chapters on ectoparasites.
• Expanded coverage of epidemiology: more on HIV, TB, malaria, infantile diarrhoea, and respiratory disease.
• Increased coverage of innate recognition, cell signalling, cancer, and pregnancy.
• New case studies to bring context to the descriptions of disease.
• New appendix on immunological techniques.

About the Author(s)

John Playfair, Emeritus Professor of Immunology, University College London Medical School, and Gregory Bancroft, Department of Immunology and Infection, London School of Hygiene and Tropical Medicine

Table of Contents

The infectious organisms
1:Introduction: parasites, pathogens, and immunity
2:Viruses
3:Bacteria
4:Fungi
5:Protozoa
6:Helminths (worms)
7:Ectoparasites
8:Prions
9:Disease: virulence and susceptibility
The immune system
10:Defence, immunity, the immune system
11:External defences: entry and exit
12:Innate immunity
13:How pathogens escape innate immunity
14:Disease due to innate immunity
15:Immunodeficiency I: primary defects of innate immunity
16:Adaptive immunity: introduction
17:B cells and antibody
18:T cells and the MHC
19:The antibody response
20:Cell-mediated responses
21:Regulation of immune responses and memory
22:How pathogens escape adaptive immunity
23:Disesase due to adaptive immunity I: hypersenstivity
24:Disease due to adaptive immunity II: autoimmunity
25:Immunodeficiency II: primary defects of adaptive immunity
26:Immunodeficiency III: secondary immunodeficiency and AIDS
The host-pathogen balance
27:Epidemiology
28:Control of infectious disease: vaccination
29:Control of infectious disease: chemotherapy
30:Control of infectious disease: public health measures
31:Viral and prion disease and immunity
32:Bacterial disease and immunity
33:Fungal disease and immunity
34:Protozoal disease and immunity
35:Helminth disease and immunity
36:Ectoparasites and immunity
37:Emerging and future infectious diseases

Reviews

"Infectious disease affects everyone. If you are hoping to understand the mechanism of infections and immunity at an introductory level, then you will find this an excellent reference book: my copy is well thumbed and already sports a forest of bookmarks." - Susan Omar, The Biologist