Immunology

Description

Immunology offers the most contemporary perspective on the science available, providing a clear, easy-to-follow introduction to the discipline suitable for undergraduate students. In a course where students often get lost in vast amounts of detail and the sheer complexity of the immune response, Immunology helps students see "the big picture" with an approachable narrative that presents the exquisite details of immunology while emphasizing the connections between key themes that students so often lose sight of when learning the material.

• Learning Objectives: Learning Objectives guide student learning of each chapter's key questions.
• Checkpoint Questions: End-of-section Checkpoint Questions reinforce student learning by focusing on the main concepts from each section.
• Chapter Summaries: Each chapter concludes with a summary of essential points covered in the exploration of each key question.
• Case Studies: Advanced undergraduate immunology courses tend to draw students who aspire to careers in health-related professions.
• Emerging Science: Examples of modern research in immunology give students both a connection to the latest technology and a means to practice understanding of primary literature.
• Key Discoveries: This text rests on the bedrock of research presented in primary literature.
• Evolution and Immunity: This feature helps students see the bigger picture of the immune system by exploring the evolutionary connections of immune systems from diverse organisms.
• Process Diagrams: Carefully thought-out and precisely rendered Process Diagrams walk readers through each step of key processes.
• Dynamic detail: Exquisitely drawn illustrations give students insight into cellular and molecular details they can otherwise only imagine.
• Making Connections: A signature feature of the book, Making Connections relates material students are reading about in one chapter to concepts and mechanisms they have learned about in previous chapters.

About the Author(s)

Stephen Juris

Stephen J. Juris is Associate Professor at Central Michigan University. He received his PhD from the University of Michigan and completed a postdoctorate at Harvard Medical School. Stephen’s research interests focus on the role of bacterial toxins in bacterial pathogenesis. His dissertation work was conducted on Yersinia pestis (causative agent of the bubonic plague) and its role in shutting down the immune response. His postdoctoral work examined the biochemical and biophysical action of anthrax toxin, including transport across endosomal membranes and action within cells. His current research at CMU focuses on a toxin made by Vibrio cholerae (causative agent of cholera) and the role the toxin plays in disruption of the cytoskeleton in intestinal epithelial cells. During his tenure at CMU, he has taught courses in Immunology, Bacterial Pathogenesis, Biochemistry, Cell Biology, and others. When he is not in the lecture hall or in the lab, he enjoys running, golf, and spending time with his

family and friends.

Table of Contents

1. Introduction to Immunology and the Immune System
2. Innate Immunity
3. The Complement System
4. Overview of Adaptive Immunity
5. Development of T Lymphocytes
6. Antigen Recognition by T Lymphocytes
7. T Cell-Mediated Adaptive Immunity
8. Development of B Lymphocytes
9. Immunoglobulins, Antibodies, and B-Cell Diversity
10. B Cell-Mediated Adaptive Immunity
11. Immunological Memory and Vaccination
12. Mucosal Immunity
13. Pathogen Evasion of the Immune System
14. Immunodeficiencies
15. Allergies and Hypersensitivity Reactions
16. Autoimmune Diseases
17. Transplantation and Immune Responses
18. Cancer and the Immune System
Appendices
Glossary
Index
The Immunologist's Toolbox (online only)

Reviews

"The more I read, the more excited I am about this book." " - -Shira Rabin, University of Louisville

"I am excited about this text. It is very easy to read and has the appropriate level of detail for my students." " - -Denise Slayback-Barry, Indiana University Purdue University Indianapolis

"'Making Connections' is an absolutely amazing feature. It solves, to some extent, the biggest challenge in teaching immunology to undergraduates, which is to tie together different concepts." " - -Madhura Pradhan, The Ohio State University

"The explanations of the biology are concise, clear, and easy to understand. I really like the inclusion of the key discoveries and related questions. The author does a nice job of providing a general introduction." " - -Michael Zimmer, Purdue University Northwest

"My course is structured to include active learning. I offer many group activities, including small-group discussions, case studies, student-made videos, etc. Many of the questions in the Juris chapters align well with how I teach and would be easy to incorporate into active learning assignments." " - -Kelly Woytek, Texas State University