Human Virology

Description

Written by leading authors in the field with both clinical and molecular expertise, Human Virology provides an accessible introduction to this fascinating and important field, making the text ideal for students encountering virology for the first time.

• Written by leading authors in the field, with expertise in both molecular and clinical virology
• Case studies, written by practising doctors, help bring the subject to life and link theory to practice
• Short, focused, chapters help to convey the key points of a subject which is often bewildering in its detail

New to this edition

• Many of the figures have been redrawn to illustrate the underlying molecular detail of viral pathogenesis
• New 'hot topic' boxes outline cutting-edge areas of research in virology
• The viruses in Part 2 are now categorized under the Baltimore Scheme, making it easier to appreciate the commonalities and differences between viruses in the same family
• Further molecular detail integrated into the text to illustrate the mechanisms by which viruses cause disease, and how they evade the immune system.

About the Author(s)

John Oxford, Emeritus Professor of Virology, Queen Mary, University of London, Paul Kellam, Professor of Virus Genomics, Imperial College London, and VP for Vaccines & Infectious Disease at Kymab Ltd, and Leslie Collier, Emeritus Professor of Virology, University of London

John Oxford is Professor of Virology at St. Bartholomew's and The Royal London School of Medicine and Dentistry at the University of London. He is the co-author of two standard texts on Influenza and Virology and has published 250 scientific papers throughout the world. Professor Oxford serves as the Scientific Director of hVIVO Ltd., the College's research virology company.

Paul Kellam is Professor of Virus Genomics, Imperial College London, and VP for Vaccines & Infectious Disease at Kymab Ltd.

Leslie Collier was from 1978 to 1986 Professor of Virology at the London Hospital Medical College, being succeeded in this post by John Oxford.

Table of Contents

Part 1: General principles
1:Virology: how it all began and where it will go next
2:General properties of viruses
3:Viral replication and genetics
4:How viruses cause disease
5:Resistance of the human body to virus infections
6:Viruses and the community: the science and practice of epidemiology
Part 2: Specific viruses
Group 1 - Positive sense single-stranded RNA viruses
7:Picornaviruses: polio, hepatitis A, enterovirus, and common cold
8:Astroviruses: gastroenteritis agents
9:Calciviruses: norovirus causing vomiting and diarrhoea
10:Hepatitis E
11:Togaviruses: mosquito-borne, Chikungunya, and teratogenic rubella
12:Flaviviruses: yellow fever, dengue fever, and hepatitis C
13:Coronaviruses (including SARS CoV and MERS CoV)
Group 2 - Negative-sense single-stranded RNA viruses
14:Orthomyxoviruses: influenza A, B, C
15:Arenaviruses: Lassa and haemorrhagic fevers
16:Bunyaviruses: Hanta, phlebo, and nairo
17:Paramyxoviruses: measles, RSV, mumps, parainfluenza, metapneumovirus, and zoonotic henipaviruses
18:Filoviruses: zoonotic Marburg, and Ebola
19:Rabies: zoonotic rabies
Group 3 - Double-stranded RNA viruses
20:Reoviruses: diarrhoea-causing rotaviruses
Group 4 - Double-stranded DNA viruses
21:Polyomaviruses
22:Papillomaviruses
23:Herpesviruses: herpetic lesions, zoster, cancer, and encephalitis
24:Smallpox: human disease eradicated but zoonotic pox virus infections common
25:Adenovirus: respiratory, eye, and gastroenteritis viruses
Group 5 - Single-stranded DNA viruses
26:Parvovirus
Group 6 - Single-stranded positive sense RNA with an RT
27:Retroviruses: HIV-1 and -2 and HTLV
Group 7 - Circular double-stranded DNA viruses with an RT
28:Hepadnaviruses: hepatitis B and D
Part 3: Practical aspects
29:The clinical virology laboratory
30:Control of viral disease by immunization
31:Antiviral chemotherapy

Reviews

"Without reservation. I will be recommending this edition. I will be reaching for my copy of this book and lending it to trainees. The general principles section is short but very well-put together - impressive. Subsequent chapters are organised as per Baltimore classification of viruses - this approach gives an ease of use to students that was remarked upon by the two students that I lent the book to and was obvious to me." - Dr Conall P Mccaughey, Consultant Virologist, Regional Virus Laboratory, Kelvin Laboratories, The Royal Hospitals Trust, Belfast

"The book is exceptionally well-written in consistent and clear style. The writers have thought about the readers understanding. The clinical case studies are brilliant - superbly put together aimed at contextualising and making memorable the content. Several of them will be great resources to teachers. I thoroughly enjoyed reading this book as did the two students that I lent it to." - Dr Conall P Mccaughey, Consultant Virologist, Regional Virus Laboratory, Kelvin Laboratories, The Royal Hospitals Trust, Belfast

Additional Resources

The Online Resource Centre to accompany Human Virology features:
For students:
·multiple-choice questions for self-directed learning
·Web links to online animations and videos

For lecturers:
·Figures from the book in electronic format, ready to download