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Cover

Genetic Analysis

Genes, Genomes, and Networks in Eukaryotes

Third Edition

Philip Meneely

April 2020

ISBN: 9780198809906

480 pages
Paperback
265x195mm

Price: £49.99

Genetic Analysis applies the combined power of molecular biology, genetics, and genomics to explore how the priniciples of genetics can be used as analytical tools to solve biological problems.

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Description

Genetic Analysis applies the combined power of molecular biology, genetics, and genomics to explore how the priniciples of genetics can be used as analytical tools to solve biological problems.

  • The logic and strategy of genetic analysis in one semester shows you how the combined power of molecular biology, genetics, and genomics can be applied to solve biological questions
  • Uses established principles of genetics as methods to analyse larger problems in biology
  • Illustrates the conceptual basis of key analytical tools with carefully selected examples from a range of model organisms, and encourages the reader to look beyond the examples to see how these tools can be used to probe a wide range of biological problems
  • Covers the latest and most powerful experimental tools to provide a state-of-the-art review of the field, giving insights into gene networks and interactions
  • Text boxes and extended case studies enable the reader to fully get to grips with how genetic tools can be used to understand biological systems
  • The online resources feature additional materials for teachers and students, enhancing the educational value of the text

New to this edition

  • A new chapter on genome editing with focus on the CRISPR-Cas 9 system
  • New content on the analysis of gene activity using temperature-sensitive mutations and mosaics
  • Increased coverage of epigenetics, updated with the latest developments in the field
  • Expanded use of case studies to guide students through examples of genetic analysis
  • A new learning feature called 'Literature Link' connects the chapter content to cutting-edge research

About the Author(s)

Philip Meneely, Professor of Biology, Department of Biology, Haverford College, PA, USA

Table of Contents

    1: The Basis for Genetic Analysis
    2: Genomes, Chromosomes, and Epigenetics
    3: Model Organisms and Their Genomes
    4: Identifying and Classifying Mutants
    5: Connecting Phenotypes with DNA Sequences
    6: Mutant Phenotypes and Gene Activity
    7: Reverse Genetics: Editing genes in yeast and mice
    8: Genome Editing
    9: Genome-Wide Mutant Screens
    10: Gene Interactions: Suppressors and Synthetic Enhancers
    11: Epistasis and Genetic Pathways
    12: Pathways, Networks, and Phenotypes

Reviews

"Review from previous edition An excellent example of a modern textbook, Genetic Analysis is a readable and stimulating introduction to this rapidly developing topic... [It] will earn its place on a biology or genetics student's bookshelf." - David Slingsby, The Biologist

"It is, in many ways, the book I have been looking for since I started to teach this course: a book that teaches methods of genetic analysis and is suitable for a senior-level course. " - Dr Steve Mount, Department of Cell Biology and Molecular Genetics, University of Maryland, USA )

"I love this text. I have not seen a text with as much current information on the most important aspects of genetics and genomics today. " - Professor Christine Rushlow, Department of Biology, New York University, USA

"This textbook is one of the few that can be used for an advanced undergrad/beginning grad level course. It is ideal for a class that uses the primary literature as a major part of the reading and discussion in the class. " - Dr Brian Condie, Department of Genetics, University of Georgia

Additional Resources

The online resources to accompany Genetic Analysis feature the following material for teachers and students:

For students:
- Additional case studies and text boxes to complement and add to those found in the book
- Practice problems and solutions to test your knowledge of the concepts presented, and help you to master them
- Online datasets with which to practice analytic techniques

For registered adopters of the book:
· Figures from the book in electronic format, ready to download.
· Journal clubs - suggested papers and discussion questions linked to topics covered in the book.