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Genetic Analysis

Genes, Genomes, and Networks in Eukaryotes

Third Edition

Philip Meneely

April 2020

ISBN: 9780198809906

496 pages

In Stock

Price: £57.99

Genetic Analysis applies the combined power of molecular biology, genetics, and genomics to explore how the priniciples of genetics can be used as analytical tools to solve biological problems.



Genetic Analysis applies the combined power of molecular biology, genetics, and genomics to explore how the priniciples of genetics can be used as analytical tools to solve biological problems.

  • The logic and strategy of genetic analysis in one semester shows you how the combined power of molecular biology, genetics, and genomics can be applied to solve biological questions
  • Uses established principles of genetics as methods to analyse larger problems in biology
  • Illustrates the conceptual basis of key analytical tools with carefully selected examples from a range of model organisms, and encourages the reader to look beyond the examples to see how these tools can be used to probe a wide range of biological problems
  • Covers the latest and most powerful experimental tools to provide a state-of-the-art review of the field, giving insights into gene networks and interactions
  • Text boxes and extended case studies enable the reader to fully get to grips with how genetic tools can be used to understand biological systems
  • The online resources feature additional materials for teachers and students, enhancing the educational value of the text
  • Also available as an e-book with functionality, navigation features, and links that offer extra learning support

New to this edition

  • A new chapter on genome editing with focus on the CRISPR-Cas 9 system
  • New content on the analysis of gene activity using temperature-sensitive mutations and mosaics
  • Increased coverage of epigenetics, updated with the latest developments in the field
  • Expanded use of case studies to guide students through examples of genetic analysis
  • A new learning feature called 'Literature Link' connects the chapter content to cutting-edge research

About the Author(s)

Philip Meneely, Professor of Biology, Department of Biology, Haverford College, PA, USA

Table of Contents

    1:The Basis for Genetic Analysis
    2:Genomes, Chromosomes, and Epigenetics
    3:Model Organisms and Their Genomes
    4:Identifying and Classifying Mutants
    5:Connecting Phenotypes with DNA Sequences
    6:Mutant Phenotypes and Gene Activity
    7:Reverse Genetics: Editing genes in yeast and mice
    8:Genome Editing
    9:Genome-Wide Mutant Screens
    10:Gene Interactions: Suppressors and Synthetic Enhancers
    11:Epistasis and Genetic Pathways
    12:Pathways, Networks, and Phenotypes


"Review from previous edition An excellent example of a modern textbook, Genetic Analysis is a readable and stimulating introduction to this rapidly developing topic... [It] will earn its place on a biology or genetics student's bookshelf." - David Slingsby, The Biologist

"It is, in many ways, the book I have been looking for since I started to teach this course: a book that teaches methods of genetic analysis and is suitable for a senior-level course. " - Dr Steve Mount, Department of Cell Biology and Molecular Genetics, University of Maryland, USA )

"I love this text. I have not seen a text with as much current information on the most important aspects of genetics and genomics today. " - Professor Christine Rushlow, Department of Biology, New York University, USA

"This textbook is one of the few that can be used for an advanced undergrad/beginning grad level course. It is ideal for a class that uses the primary literature as a major part of the reading and discussion in the class. " - Dr Brian Condie, Department of Genetics, University of Georgia

Additional Resources

Digital formats and resources

Genetic Analysis is supported by online resources and is available for students and institutions to purchase in a variety of formats.

The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks

The online resources to accompany Genetic Analysis feature the following material for teachers and students:

For students:
- Additional case studies and text boxes to complement and add to those found in the book
- Practice problems and solutions to test your knowledge of the concepts presented, and help you to master them
- Online datasets with which to practice analytic techniques

For registered adopters of the book:
- Figures from the book in electronic format, ready to download.
- Journal clubs - suggested papers and discussion questions linked to topics covered in the book.

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