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An Introduction to Population Genetics

Theory and Applications

Rasmus Nielsen and Montgomery Slatkin

March 2013

ISBN: 9781605351537

287 pages

In Stock

Price: £104.99

An accessible introduction to both classical and modern population genetics theories. If you are a lecturer interested in adopting this title for your course, please contact your Oxford representative to arrange a local price.



Published by Sinauer Associates, an imprint of Oxford University Press.

About the Author(s)

Rasmus Nielsen, University of California at Berkeley, and Montgomery Slatkin, University of California at Berkeley

Rasmus Nielsen is a Professor in the Departments of Integrative Biology and Statistics at the University of California at Berkeley. He first came to Berkeley to pursue a Ph.D. in Population Genetics (with advisor, now coauthor, Montgomery Slatkin), having already earned a Masters in Biology from the University of Copenhagen. Dr. Nielsen was awarded both a Fullbright Fellowship and a Sloan Research Fellowship, and received the Ole Rømer Award and the ElitForsk Award. He edited the book Statistical Methods in Molecular Evolution (Statistics for Biology and Health) (2005). Dr. Nielsen and lab members work on statistical and computational methods and their applications in population genetics, medical genetics, molecular ecology, and molecular evolution.

Montgomery Slatkin is a Professor in the Department of Integrative Biology at the University of California at Berkeley. He earned a B.S. in Mathematics from MIT, and a Ph.D. in Applied Biomathematics from Harvard University (with George F. Carrier and William H. Bossert). Dr. Slatkin is editor of Evolution: Essays in Honour of John Maynard Smith (with P. J. Greenwood and P. H. Harvey) and Modern Developments in Theoretical Population Genetics (with M. Veuille, Oxford University Press). He was elected a member of the American Academy of Arts and Science (1997), awarded a Guggenheim Fellowship (1999-2000), and received the Sewall Wright Award of the American Society of Naturalists (2000). His research focus is population genetics and genomics, particularly of humans and archaic human relatives.

Table of Contents

    1:Allele Frequencies, Genotype Frequencies, and Hardy-Weinberg Equilibrium
    2:Genetic Drift and Mutation
    3:Coalescence Theory: Relating Theory to Data
    4:Population Subdivision
    5:Inferring Population History and Demography
    6:Linkage Disequilibrium and Gene Mapping
    7:Selection I
    8:Selection in a Finite Population
    9:The Neutral Theory and Tests of Neutrality
    10:Selection II: Interaction and Conflict
    11:Quantitative Genetics


"This book is the first textbook I have encountered that takes the coalescent as an integrated, normal aspect of modern population genetics. For anyone wanting to teach this subject, or indeed learn it, Nielsen and Slatkin's recent book presents a refreshingly modern synthesis." - Julia Sigwart, Systematic Biology

"Overall, An Introduction to Population Genetics: Theory and Applications will be a welcome addition to the bookshelf of any aspiring biology student. This is an ideal textbook for a short semester or quarter-long population genetics course, and I wholeheartedly recommend it. Furthermore, practicing geneticists and bioinformaticians would benefit from the taste of population genetics that this volume offers." - Joseph Lachance, The Quarterly Review of Biology

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