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An Introduction to Drug Synthesis

Graham L. Patrick

15 January 2015

ISBN: 9780198708438

592 pages

In Stock

Price: £47.99

The only text to provide a full exploration of the role of organic synthesis in drug design and development.


An Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.

  • An introduction to the central role of organic synthesis in the development of therapeutically useful drugs
  • Written by an author whose name has become synonymous with clear and engaging explanations
  • The extensive use of examples and case studies reinforces the relevance of the subject matter to the synthesis of drugs and highlights the different synthetic strategies available
  • An Online Resource Centre provides additional teaching and learning resources to augment the printed text

About the Author(s)

Graham L. Patrick, University of the West of Scotland

Graham Patrick is a lecturer in Organic Chemistry and Medicinal Chemistry at the University of the West of Scotland, Glasgow. He is the author of four other undergraduate textbooks covering medicinal chemistry and organic chemistry, including Introduction to Medicinal Chemistry, which is now in its fifth edition.

Table of Contents

    PART A: Concepts
    1:The drug discovery process
    2:Drug synthesis
    4:Cyclic systems in drug synthesis
    5:The synthesis of chiral drugs
    6:Combinatorial and parallel synthesis
    PART B: Applications of drug synthesis in the drug development process
    7:Synthesis of lead compounds
    8:Analogue synthesis in drug design
    9:Synthesis of natural products and their analogues
    10:Chemical and process development
    11:Synthesis of isotopically labelled compounds
    PART C: Design and synthesis of selected antibacterial agents
    12:Design and synthesis of tetracyclines
    13:Erythromycin and macrolide antibacterial agents
    14:Quinolones and fluoroquinolones


"This is a well-written guide to many of the key concepts in the application of organic synthesis to drug discovery and development." - Doody's Notes

Additional Resources

Online Resource Centre
An Introduction to Drug Synthesis is supported by an Online Resource Centre featuring:

For registered adopters:
- Figures from the book in electronic format;

For students:
- A suite of multiple-choice questions to support the learning process;
- Additional case studies
- More detailed descriptions of key synthetic reactions, as a source of further reference.