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A Primer of Human Genetics

Greg Gibson

December 2014

ISBN: 9781605353135

442 pages
Paperback

In Stock

Price: £99.99

Helps students understand and appreciate the extraordinary shifts in human genetics that have accompanied the arrival of genomics. If you are a lecturer interested in adopting this title for your course, please contact your Oxford representative to arrange a local price.

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Description

Published by Sinauer Associates, an imprint of Oxford University Press.

A Primer of Human Genetics is an introductory textbook designed to give students the foundation they need to understand and appreciate the extraordinary shifts in human genetics that have accompanied the arrival of genomics. The book lays out the key concepts of human evolution, quantitative genetics, and personalized medicine before describing the tools that are missing from most contemporary textbooks: genome-wide association studies, whole-genome resequencing, gene expression and epigenome profiling, and integrative genomics.

About the Author(s)

Greg Gibson

Greg Gibson is Professor and Director of the Center for Integrative Genomics at the Georgia Institute of Technology, and holds an adjunct appointment at Emory University School of Medicine. He earned a Bachelor's Degree in Biology at the University of Sydney and a Ph.D. in Cell Biology at the University of Basel (with Walter J. Gehring). He worked for 15 years with the fruitfly Drosophila melanogaster, mostly while at North Carolina State University, during which time he wrote A Primer of Genome Science with Spencer Muse. Dr. Gibson serves on the editorial boards of several leading journals, and is a Fellow of the American Association for the Advancement of Science. His current research is in quantitative genetics and genomics, focusing on environmental and genetic sources of human variability, the regulation of gene expression in immunogenomics, and predictive health.

Table of Contents

    PART I. FOUNDATIONS
    1:Conceptual Foundations
    2:The Human Genome
    3:Human Evolution
    4:Normal Variation
    5:Personalized Genomics
    PART II. TOOLS
    6:Genome-Wide Association Studies
    7:Whole-Genome and Whole-Exome Sequencing
    8:Gene Expression Profiling
    9:The Epigenome
    10:Integrative Genomics
    PART III. DISEASES
    11:Immune-Related Disease
    12:Metabolic Disease
    13:Cardiovascular Disease
    14:Cancer Genetics
    15:Neurological and Psychiatric Disorders
    16:Genetics of Aging

Reviews

"This text excites the avid student to pursue research in genetics by providing insightful resources in a concise manner. Additionally, this text hits the mark on providing emerging methods and technologies into a quick reference with appended summary bibliography at the end of each chapter. The illustrations are clear and convey the overall broad aims without getting into the minutiae. The author does a great service to the field by providing this informative resource." - Eric M. Johnson Chavarria, Yale Journal of Biology and Medicine

Additional Resources

For Instructors


Available to qualified adopters, the Instructor's Resource Library includes electronic versions of all of the textbook's figures, photos, and tables. All images are provided as both low- and high-resolution JPEGs, and have been formatted and optimized for excellent legibility and projection quality. In addition, a ready-to-use PowerPoint presentation of all figures and tables is provided for each chapter of the textbook.

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