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A Primer of Genome Science

Third Edition

Greg Gibson and Spencer V. Muse

January 2009

ISBN: 9780878932368

344 pages

Price: £119.99

An introduction to genome science covering bioinformatic principles and experimental strategies alongside experimental methods. If you are a lecturer interested in adopting this title for your course, please contact your Oxford representative to arrange a local price.



Published by Sinauer Associates, an imprint of Oxford University Press.

Genome science has matured as a discipline to the point where it is now incorporated as a regular part of the genetics curriculum in universities. A Primer of Genome Science, Third Edition, bridges the gap between standard genetics textbooks and highly specialized, technical, and advanced treatments of the subdisciplines.

About the Author(s)

Greg Gibson and Spencer V. Muse

Greg Gibson is Professor and Director of the Center for Integrative Genomics at the Georgia Institute of Technology, and holds adjunct appointments at Emory University School of Medicine, North Carolina State University, and the Sanford-Burnham Medical Research Institute. He earned a Bachelor's Degree in Biology at the University of Sydney and a Ph.D. in Cell Biology at the University of Basel (with Walter J. Gehring). Dr. Gibson serves on the editorial boards of several leading journals, and is a Fellow of the American Association for the Advancement of Science. His research is in quantitative genetics and genomics, focusing on human variability and predictive health. He has also worked with the fruitfly Drosophila melanogaster extensively.

Spencer V. Muse is Associate Professor in the Department of Statistics, Bioinformatics Research Center at North Carolina State University. He earned a Bachelor's Degree in Statistics and a Ph.D. in Statistics and Genetics, both at NCSU (the latter with Bruce Weir and Trudy Mackay). Dr. Muse was the recipient of a Sloan Foundation Young Investigator Award (1997-2001). His research is in molecular evolution and bioinformatics.

Table of Contents

    1:Genome Projects: Organization and Objectives
    2:Genome Sequencing and Annotation
    3:Genomic Variation
    4:Gene Expression and the Transcriptome
    5:Proteomics and Functional Genomics
    6:Integrative Genomics


"In realizing that the field is unlikely to slow down any time soon, by simply demonstrating that they can keep pace with it, the authors have again succeeded with a well-organized view of the present and future of genome science." - Brian C. Verrelli, The Quarterly Review of Biology

"With the huge data sets that are produced in genomic studies, many mathematicians and computer sciences researchers, as well as cell biologists and classical geneticists, are being drawn into working on problems from a genomics perspective, and they will profit greatly from reading this book. The work also provides an affordable introduction that is suited to advanced academic coursework. As in earlier editions, the illustrations, special topic boxes, and hands-on exercises are superb. Highly recommended." - K. A. Newman, Choice

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