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Elliott & Elliott: Biochemistry and Molecular Biology 4e

Chapter 32

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One-page note about this cell-surface receptor, one of the main triggers of death in cells of the immune system.

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News and Views summary of caspase control of apoptosis.

Chen, G. and Goeddel, D. V. (2002). TNF-R1 signaling: a beautiful pathway. Science, 296, 1634-5 [DOI: 10.1126/science.1071924] [PubMed: 12040173].
Short review summarizing the engagement of tumour necrosis factor with its receptor and the pathway leading to the downstream events, apoptosis and NF-KB activation.

Hooper, N. M., Ed. (2002). Proteases in biology and medicine. Essays Biochem., 36, 1-167.
A complete issue with 12 reviews on many aspects of proteases, including caspases, cancer, proteasomes, and blood clotting.

Johnstone, R. W., Ruefli, A. A., and Lowe, S. W. (2002). Apoptosis: a link between cancer genetics and chemotherapy. Cell 108, 153-64 [DOI: 10.1016/S0092-8674(02)00625-6] [PubMed: 11832206].

Chakravati, D. and Hong, R. (2003). SET-Ting the stage for life and death. Cell 112, 589-91 [DOI: 10.1016/S0092-8674(03)00151-X].

Apoptosis by granzyme release

Downward, J. (2003). Metabolism meets death. Nature, 424, 896-7 [DOI: 10.1038/424896a] [PubMed: 12931174].
A News and Views article on a protein that controls cell death found in complex with a protein involved in glucose metabolism.

Liu, C. Y. and Kaufman, R. (2003). The unfolded protein response. J. Cell Sci., 116, 1861-2 [DOI: 10.1242/jcs.00408].
Brief account of apoptosis mechanisms

Newmeyer, D. D. (2003). Mitochondria: releasing power for life and unleashing the machineries of death. Cell 112, 481-90 [DOI: 10.1016/S0092-8674(03)00116-8] [PubMed: 12600312].

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Discusses phagocytosis of apoptotic cell ?corpses?

Varfolomeev, E. E. and Ashkenazi, A. (2004). Tumor necrosis factor: an apoptosis juNKie? Cell 116, 491-7 [DOI: 10.1016/S0092-8674(04)00166-7] [PubMed: 14980217].

Halestrap, A. (2005) A pore way to die. Nature, 434, 578-9 [DOI: 10.1038/434578a] [PubMed: 15800609].
A News and Views article comparing apoptosis and necrosis

Lavrik, I., Golks, A., and Krammer P. H. (2005). Death receptor signalling. J. Cell Sci., 118, 265-7 [DOI: 10.1242/jcs.01610].
A ?Cell Science at a Glance? article

Arian, C., Brumatti, G., and Martin, S. J. (2006). Apaptosomes: protease activation platforms to die from. Trends Biochem. Sci., 31, 243-7 [DOI: 10.1016/j.tibs.2006.03.004].

Rutkowski, D. T. and Kaufman, R. J. (2007). That which does not kill me makes me stronger: adapting to chronic ER stress. Trends Biochem. Sci., 32, 400-6 [DOI: 10.1016/j.tibs.2007.09.003].
Deals with response to accumulation of unfolded proteins in ER.