Elliott & Elliott: Biochemistry and Molecular Biology 4e
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A News and Views article on signal peptide cleavage as the transported polypeptide emerges into the lumen of the ER.
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Refers to protein transport through the ER membrane.
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Two distinct modes mediated by ?translocons? - the macro molecular complex that translocates proteins across membranes.
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Reviews general principles and specific diseases
Bonifacino, J. S. and Traub, L. M. (2003). Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu. Rev. Biochem., 72, 395-447 [DOI: 10.1146/annurev.biochem.72.121801.161800].
A research-level review
COP-coated vesicle formation and targeting
Edwardson, J. M. (1998). Membrane fusion: all done with SNARE pins. Curr. Biol., 8, R390-3 [DOI: 10.1016/S0960-9822(98)70245-3].
All about SNARE proteins and transport vesicle targeting
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Brief summary of v-SNARES and t-SNARES
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A minireview that discusses why different coat proteins are used for the transport of vesicles.
Schmid, S. L. and Damke, H. (1995). Coated vesicles: a diversity of form and function. FASEB J., 9, 1445-53.
Reviews the different ways in which coated vesicles are budded off from the Golgi and other membranes.
Schekman, R. and Orci, L. (1996). Coat proteins and vesicle budding. Science, 271, 1526-33 [DOI: 10.1126/science.271.5255.1526] [PubMed: 8599108].
A review of vesicle transport and their role in sorting of proteins.
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Discussing formation of transport vesicles
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Shows that the Zellweger syndrome primary cause is a defect in the synthesis of a peroxisome assembly protein.
McNew, J. A. and Goodman, J. M. (1995). The targeting and assembly of peroxisomal proteins: some old rules do not apply. Trends Biochem. Sci., 21, 54-8 [DOI: 10.1016/0968-0004(96)80866-8].
Reviews evidence that folded proteins are imported into peroxisomes as such.
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Comprehensive review of peroxisomal biogenesis
Pfanner, N. and Meijer, M. (1997). Mitochondrial biogenesis: the TOM and TIM machine. Curr. Biol., 7, R100-3 [DOI: 10.1016/S0960-9822(06)00048-0].
Reviews the field
Koehler, C. M., Merchant, S., and Schatz, G. (1998). How membrane proteins travel across the mitochondrial intermembrane space. Trends Biochem. Sci., 24, 428-32 [DOI: 10.1016/S0968-0004(99)01462-0].
Deals with the special proteins needed to conduct hydrophobic proteins across the aqueous intermembrane space. Deficiencies in these lead to blindness and deafness.
Neupert, W. and Herrmann, J. M. (2007). Translocation of proteins into mitochondria. Annu. Rev. Biochem., 76, 723-49 [DOI: 10.1146/annurev.biochem.76.052705.163409].
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A highly readable personal review of mitochondrial assembly and how the field, in which the author has played a major part, has developed.
Mattaj, I. W. and Englmeir, L. (1998). Nucleocytoplasmic transport: the soluble phase. Annu. Rev. Biochem, 67, 265-306 [DOI: 10.1146/annurev.biochem.67.1.265].
A comprehensive review
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Concise News and Views article describing the mechanism of nuclear-cytoplasmic transport.
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News and Views article describing work by Rout and colleagues, which gives a complete structure of the nuclear pore.
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Abeijon, C. and Hirschberg, C. B. (1992). Topography of glycosylation reactions in the endoplasmic reticulum. Trends Biochem. Sci., 17, 32-6 [DOI: 10.1016/0968-0004(92)90424-8].
Reviews the different protein glycosylation reactions occurring in the endoplasmic reticulum.