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Oxford University Press - Online Resource Centres

Elliott & Elliott: Biochemistry and Molecular Biology 4e

Chapter 07

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Membrane lipids and movement

Higgins, C. F. (1994). Flip-flop: the transmembrane translocation of lipids. Cell 79, 393-5 [DOI: 10.1016/0092-8674(94)90248-8] [PubMed: 7954806].
Discusses how lipids get to where they should be and how asymmetry of the lipid bilayer is achieved.

Rooney, S. A., Young, S. L., and Mendelson, C. R. (1994). Molecular and cellular processing of lung surfactant. FASEB J., 8, 957-67.
Reviews a more physiological role of phospholipids - that of lining the alveoli.

Shin, J.-S. and Abraham, S. N. (2001). Caveolae - not just craters in the cellular landscape. Science, 293, 1447-8 [DOI: 10.1126/science.1061079] [PubMed: 11520975].
Caveolae are small pits in mammalian cell membranes, now attracting much attention.

Deurs, B., et al. (2003). Caveolae: anchored, multifunctional platforms in the lipid ocean. Trends Cell Biol., 13, 92-100 [DOI: 10.1016/S0962-8924(02)00039-9].

Mozaffarian, D., Katan, M. B., Ascherio, A., Stampfer, M. J., and Willett, W. C. (2006). Trans fatty acids and cardiovascular disease. New Engl. J. Med., 354, 1601-13 [DOI: 10.1056/NEJMra054035].

Membrane proteins

Macdonald, C. (1985). Gap junctions and cell-cell communication. Essays Biochem., 21, 86-118.

Von Heijne, G. (1994). Membrane proteins: from sequence to structure. Annu. Rev. Biophys. Biomol. Struct., 23, 167-92 [DOI: 10.1146/annurev.bb.23.060194.001123].
A review tracing the steps from sequence to structure of integral membrane proteins.

Von Heijne, G. (1995). Membrane protein assembly: rules of the game. BioEssays, 17, 25-30 [DOI: 10.1002/bies.950170107] [PubMed: 7702590].
Discussion of how proteins can be ?stitched? into membranes with multiple transmembrane helices.

Avery, J. (1999). Synaptic vesicle proteins. Curr. Biol., 9, R624 [DOI: 10.1016/S0960-9822(99)80404-7].
A single-page quick guide

Borst, P. and Elferink, R. O. (2002). Mammalian ABC transporters in health and disease. Annu. Rev. Biochem., 71, 537-92 [DOI: 10.1146/annurev.biochem.71.102301.093055].

Kaplan, J. H. (2002). Biochemistry of Na, K-ATPase. Annu. Rev. Biochem., 71, 511-35 [DOI: 10.1146/annurev.biochem.71.102201.141218].

Ion channels and porins

Neher, E. and Sakmann, B. (1992). The patch clamp technique. Sci. Am., 266(3), 44-51.
Enables studies to be made on ligand-gated and voltage-gated ion channels.

Changeux, J.-P. (1993). Chemical signalling in the brain. Sci. Am., 269(5), 30-7.
The acetylcholine receptor and how it works

Catterall, W. A. (1995). Structure and function of voltage-gated ion channels. Annu. Rev. Biochem., 64, 493-531 [DOI: 10.1146/annurev.bi.64.070195.002425].
Covers sodium, calcium, and potassium channels

Doyle, D. A. (1998). The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science, 280, 69-76 [DOI: 10.1126/science.280.5360.69] [PubMed: 9525859].

Choe, S., Kreusch, A., and Pfoffinger, P. J. P. (1999). Towards the three-dimensional structure of voltage-gated potassium channels. Trends Biochem. Sci., 24, 345-9 [DOI: 10.1016/S0968-0004(99)01440-1].

Kozono, D., et al. (2002). Aquaporin water channels: atomic structure and molecular dynamics meet clinical medicine. J. Clin. Invest., 109, 1395-9 [DOI: 10.1172/JCI15851].

Mitter, G. (2003). The puzzling portrait of a pore. Science, 300, 2020-2 [DOI: 10.1126/science.300.5628.2020].
Reviews new light on the mechanism of voltage-gated potassium channels in neurons.

Blaustein, R. O. and Miller, C. (2004). Ion channels: shake, rattle or roll? Nature, 427, 499-500 [DOI: 10.1038/427499a] [PubMed: 14765181].
Short News and Views article about the voltage sensor in voltage-gated ion channels.

Roosild, T. P., L?, K.-T., and Choe, S. (2004). Cytoplasmic gatekeepers of K+-channel flux: a structural perspective. Trends Biochem. Sci., 29, 39-45 [DOI: 10.1016/j.tibs.2003.11.008].
Structural knowledge of K+-selective channels has started to provide a basis for understanding the biophysical machinery underlying their electrophysiological properties.