Oxford University Press - Online Resource Centres

Wolpert, Tickle & Martinez Arias: Principles of Development 5e

Signalling pathway animations

View the signaling aminations using the links below or by scanning the QR codes in the book using your mobile device.

The Notch signaling pathway
Animation depicting the Notch intracellular signaling pathway, which is involved in many important developmental processes determining cell fate. For more information, see page 212.
http://youtu.be/axkDX0XZyN0

The Hedgehog signaling pathway in Drosophila
Animation depicting the Hedgehog signaling pathway in Drosophila, which results in the activation of target genes such as wingless (wg), decapentaplegic (dpp), and engrailed (en). For more information, see page 82.
http://youtu.be/w1xXD9kss2w

The Wnt/β-catenin signaling pathway
Animation showing a simplified version of the canonical Wnt/ β-catenin signaling pathway. For more information, see page 148.
http://youtu.be/oweNT288BXo

The BMP signaling pathway
Animation depicting the BMP signaling pathway which can trigger processes such as the ventralization of mesoderm, formation of bone and cartilage, and apoptosis. For more information, see page 157.
http://youtu.be/eHB7QYVO9lw

The FGF signaling pathway
Animation depicting a simplified version of the FGF signalling pathway, which leads to changes in gene expression that can result in for example cell growth, division, or differentiation. For more information, see page 165.
http://youtu.be/DUBelRjjqvc