Transfusion and Transplantation Science

Second Edition

Edited by Neil Avent

Fundamentals of Biomedical Science

A blend of science theory and biomedical science practice make this series ideal for those seeking both the knowledge and skills to become proficient Biomedical Scientists
Case studies and other examples enrich the text, firmly rooting it in the context of clinical and biomedical practice
Self-test and discussion questions, with answers provided online, encourage students to analyze the text and develop their problem solving skills
The book is augmented by an Online Resource Centre, which includes video interviews with practicing biomedical scientists and 'in the lab' footage showing biomedical science in practice

New to this Edition:

A completely revised chapter on all human blood group systems, their antigens, genes, and function in the red cell, and including new developments in blood group genotyping.
A new chapter on haemolytic disease of the newborn and fetus, including prenatal diagnosis, current clinical management, screening of D-negative mothers, and non-invasive prenatal blood grouping.
A revised chapter on solid organ transplantation , including the clinical management of transplants, major rejection episodes, the management of transplantation by immunosuppression, and the potential of xenotransplantation to alleviate the shortfall of human organs.
All remaining chapters have been revised and updated.
Case studies have been extended to help foster an understanding of the diagnostic process, taking the reader through each clinical case from initial presentation to the interpretation of results.

Transfusion and Transplantation Science

Second Edition

Edited by Neil Avent

Fundamentals of Biomedical Science

Description

Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible.

The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis.
Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed—from microbiology to cytopathology to transfusion science.

The science of transfusion and transplantation demands a multifaceted understanding of immunology, haematology, and genetics from the biomedical scientist. Transfusion and Transplantation Science synthesizes the essential concepts of these subjects and presents them within the practical framework of the hospital banking and transplantation centre, providing you with the knowledge and skills to specialize in this discipline.

Transfusion and Transplantation Science

Second Edition

Edited by Neil Avent

Fundamentals of Biomedical Science

1:Introduction to Basic Immunology and Techniques, Neil D. Avent
2:Human Blood Group Antigens, Neil D. Avent
3:Haemolytic Disease of the Fetus and Newborn, Neil D. Avent
4:Clinical Use of Blood Components, Lionel Mohabir
5:Microbiological Testing of Blood Donations, Catherine Hyland, John Barbara, and Lionel Mohabir
6:Human Platelet Antigens (HPA) and Human Neutrophil Antigens (HNA) and their Clinical Significance, Geoff Lucas
7:Compatibility Testing and Adverse Effects, Malcolm Needs
8:Immune Mediated Red Cell Destruction, Malcolm Needs
9:Human Leucocyte Antigens (HLA) and their Clinical Significance, Neil D. Avent
10:Haematopoietic Stem Cell Transplantation and Stem Cell Plasticity, Ruth Morse and Saeed Kabrah
11:Tissue Banking, Richard Lomas, Neil D. Avent, and Vehid Salih
12:Quality Issues, Joan Jones

Transfusion and Transplantation Science

Second Edition

Edited by Neil Avent

Fundamentals of Biomedical Science

Author Information

Edited by Neil Avent, Professor of Molecular Diagnostics and Transfusion Medicine, School of Biomedical & Healthcare Sciences, Plymouth University

Professor Neil Avent is Professor of Molecular Diagnostics and Transfusion Medicine at the School of Biomedical & Healthcare Sciences of Plymouth University. He has taught transfusion and transplantation to undergraduates since 1999 and to biomedical scientists at Masters levels.

Contributors:

Contributors to the second edition
Neil D. Avent, School of Biomedical and Healthcare Sciences, Plymouth University
John Barbara, formerly of NHS Blood and Transplant
Catherine Hyland, Australian Red Cross Blood Service
Joan Jones, Welsh Blood Service
Saeed Kabrah, Department of Laboratory Medicine, Umm Al-Qura University, Saudi Arabia
Richard Lomas, NHS Blood and Transplant
Geoff Lucas, NHS Blood and Transplant
Lionel Mohabir, Welsh Blood Service
Ruth Morse, Department of Biological, Biomedical and Analytical Sciences, University of the West of England
Malcolm Needs, NHS Blood and Transplant
Vehid Salih, Plymouth University Peninsula Schools of Medicine and Dentistry

Contributors to the first edition
John Barker, Gateshead Health NHS Foundation Trust
Colin Brown, NHS Blood and Transplant
Carol Cantwell, St Marys Hospital Imperial College Healthcare NHS Trust
Bill Chaffe, East Kent Hospitals University NHS Foundation Trust
Tony Davies, NHS Blood and Transplant
Joan Jones, Welsh Blood Service
Robin Knight, Former Head of NHS Blood and Transplant Red Cell Immunohaematology Division
Richard Lomas, NHS Blood and Transplant
Geoff Lucas, NHS Blood and Transplant
Karen Madgwick, North Middlesex Hospital NHS Trust
Lionel Mohabir, Welsh Blood Service

Transfusion and Transplantation Science

Second Edition

Edited by Neil Avent

Fundamentals of Biomedical Science

Reviews and Awards

Review from previous edition Excellent teaching material for those studying Biomedical Science. - Dr Stephen F. Hughes, University of Chester

There is a clear focus on practical application of the theory in the transfusion lab. - Dr Christine Shirras, Lancaster University

The main strength is the Biomedical Science perspective. The emphasis is on transfusion practice within the laboratory: the biochemistry backs up the practical applications, not the other way round as biochemistry texts often do. - Trish Procter, Keele University