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Published: 26 December 2018

240 Pages | 41 grayscale and 45 color line figures; 8 grayscale and 9 color halftone figures


ISBN: 9780198530923

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Single-Molecule Studies of Nucleic Acids and Their Proteins

David Bensimon, Vincent Croquette, Jean-François Allemand, Xavier Michalet, and Terence Strick

Oxford Graduate Texts

  • Lucidly explains the methods for single molecule manipulations
  • Clearly describes the basis for fluorescence studies (lifetimes, rates, FRET, FCS, super-resolution microscopy, etc.) and their pitfalls
  • Discusses the various polymer models (FJC, WLC, RLC, etc.) and their relevance to the physical properties of Nucleic acids
  • Describes the use of the various methods for the study of three essential DNA (and RNA) processing enzymatic families (polymerases, helicases and topoisomerases)