Sequence-Controlled Polymers

Synthesis, Self-Assembly and Properties

Edited by Jean-Francois Lutz, Tara Y. Meyer, Makoto Ouchi, and Mitsuo Sawamoto

American Chemical Society

ACS Symposium Series

- The first book to explore the important topic of sequence-controlled polymers
- An interdisciplinary volume with contributions from experts in a range of fields

Sequence-Controlled Polymers

Synthesis, Self-Assembly and Properties

Edited by Jean-Francois Lutz, Tara Y. Meyer, Makoto Ouchi, and Mitsuo Sawamoto

American Chemical Society

Description

The present volume of the ACS Symposium series is dedicated to the emerging field of sequence-controlled polymers. The objectives of this new research discipline include the synthesis, characterization, and exploitation of synthetic macromolecules containing ordered sequences of comonomers. This topic has gained significant importance in academic polymer research during the last several years. The community, which was initially composed of a few isolated researchers, has rapidly grown in a dynamic international network. As a consequence, the first international symposium on sequence-controlled polymers was organized at the 246th American Chemical Society national meeting in Indianapolis. All the chapters in this volume are related to the invited oral presentations that were given during the symposium. This selection of papers gives an overview of the field and highlights its interdisciplinary nature.

Indeed, the symposium participants and the authors of this book are not only polymer chemists, but also organic chemists, supramolecular chemists, and physico-chemists. As a matter of fact, the design of tailor-made sequence-controlled polymers is a topic that goes beyond the traditional barriers of synthetic polymer science. Sequence-Controlled Polymers: Synthesis, Self-Assembly, and Properties will be of interest to a broad readership, as it is the first book to explore the important topic of sequence-controlled polymers. Based on its recent academic impact, it is reasonable to expect that this field of research will continue to grow in the next decades.

Sequence-Controlled Polymers

Synthesis, Self-Assembly and Properties

Edited by Jean-Francois Lutz, Tara Y. Meyer, Makoto Ouchi, and Mitsuo Sawamoto

American Chemical Society

ACS Symposium Series

Contents
Preface

1. An Introduction to Sequence-Controlled Polymers

BIOLOGICAL POLYMERS AND BIO-INSPIRED METHODS
2. The Language of Protein Polymers
3. Precision Sequence Control in Bioinspired Peptoid Polymers
4. Peptide-Polymer Conjugates as Model Systems To Explore the Functional Space of Precision Polymers
5. DNA-Templated Chemistries for Sequence Controlled Oligomer Synthesis
6. Recent Advances in Solid Phase Polymer Synthesis: Polyamides from Tailor-Made Building Blocks
7. Solid-Phase Synthesis as a Tool for the Preparation of Sequence-Defined Oligomers Based on Natural Amino Acids and Synthetic Building Blocks

SEQUENCE REGULATION IN SYNTHETIC POLYMERIZATION
8. Synthesis of Sequence-Controlled Copolymers Using Time-Regulated Additions of N-Substituted Maleimides in Styrenic Radical Polymerizations
9. RAFT for the Control of Monomer Sequence Distribution - Single Unit Monomer Insertion (SUMI) into Dithiobenzoate RAFT Agents
10. Selective Single Monomer Radical Addition via Template-Assisted Ring Closure: A Feasibility Study toward Sequence Control in Vinyl Polymers with Peptide Templates
11. Sequence-Controlled Polymers by Ruthenium-Mediated Ring-Opening Metathesis Polymerization
12. Synthesis of Side-Chain-Sequenced Copolymers Using Vinyl Oligomonomers via Sequential Single-Monomer ATRA
13. Cu(0)-Mediated Controlled/Living Radical Polymerization: A Tool for Precise Multiblock Copolymer Synthesis
14. The Rationale Behind Sequence-Controlled Maleimide Copolymers
15. Sequence-Regulated Polymers via Combination of Orthogonal Passerini Three-Component Reaction and Thiol-ene Reaction
16. Sequence-Controlled Polymerization Guided by Aryl-Fluoroaryl pi-Stacking
17. Sequence-Regulated Polymers via Living Radical Polymerization: From Design to Properties and Functions

PROPERTIES AND FUNCTIONS OF SEQUENCE-CONTROLLED POLYMERS
18. Engineering Hydrolytic Degradation Behavior of Poly(lactic-co-glycolic acid) through Precise Control of Monomer Sequence
19. Gradient Sequence pi-Conjugated Copolymers
20. Sequence-Controlled Radical Copolymerization for the Design of High-Performanced Transparent Polymer Materials
21. Dynamic Single Chain Polymeric Nanoparticles: From Structure to Function
22. Sequence-Controlled Multi-Block Glycopolymers via Cu(0) Mediated Living Radical Polymerization
23. Sequence-Controlled Ring-Opening Polymerization: Synthesis of New Polyester Structures
24. Organic Synthesis of Periodic 2D Polymers
25. Sequence Matters: Determining the Sequence Effect of Electronic Structure Properties in pi-Conjugated Polymers

Editors' Biographies
Indexes
Author Index
Subject Index

Sequence-Controlled Polymers

Synthesis, Self-Assembly and Properties

Edited by Jean-Francois Lutz, Tara Y. Meyer, Makoto Ouchi, and Mitsuo Sawamoto

American Chemical Society

ACS Symposium Series

Author Information

Jean-François Lutz is a CNRS research director, deputy director of the Institut Charles Sadron in Strasbourg, and head of the Precision Macromolecular Chemistry group. He received his doctoral degree from the University of Montpellier II (France) in 2000 and his habilitation degree from the University of Potsdam (Germany) in 2009. Before joining the CNRS, he was a post-doctoral fellow in the group of Krzysztof Matyjaszewski at Carnegie Mellon University (2001-2003) and afterwards, leader of the research group Nanotechnology for Life Science at the Fraunhofer Institute for Applied Polymer Research (2003-2010).

Tara Y. Meyer received her B.A. from Grinnell College in 1991 and her Ph.D. from the University of Iowa in 1991. Her doctoral thesis, under the supervision of Prof. Louis Messerle, focused on the reactivity of early transition metal acyl complexes. She carried out postdoctoral work at both the University of Iowa (1991-1992) under the supervision of Prof. Richard F. Jordan and the University of California, Berkeley (1992-1994) under the joint supervision of Prof. Robert G. Bergman and Bruce M. Novak. Dr. Meyer joined the faculty at the University of Pittsburgh department of Chemistry in 1994 and is a member of the McGowan Institute for Regenerative Medicine.

Makoto Ouchi is an associate professor at Kyoto University and concurrently a PRESTO researcher with Japan Science and Technology Agency (JST). He received his doctoral degree from Kyoto University in 2001 and then joined Toyota Central R&D Labs., Inc. as a researcher before moving to Graduate School of Engineering of Kyoto University as an assistant professor. He received the Young Scientist Prize of the Annual Kobe Polymer Research Symposium (2011) and the Polymer Journal Zeon Award (2012).

Mitsuo Sawamoto (b. 1951, Japan) received his B.S. (1974), M.S. (1976), and Ph.D. degrees (1979) in polymer chemistry from Kyoto University. After post-doctoral research at the University of Akron (1980-81), he joined the Department of Polymer Chemistry, Kyoto University in 1981 and has been a professor of Polymer Chemistry since 1994. He is an executive member of the Science Council of Japan (2005-), a titular member of IUPAC Polymer Division (2008-), the immediate past president of the Society of Polymer Science, Japan (SPSJ) (2008-2010), and one of the editors for the Journal of Polymer Science, Part A, Polymer Chemistry (1995-).

Contributors:

Sarah Almahdali
Athina Anastasaki
Takahiro Arima
Müge Artar
Nathalie Baradeland
C. Remzi Becer
Jonathon S. Bechtel
Kerri L. Bell
Hans G. Börner
Cyrille Boyer
Emilie Brulé
Niels ten Brummelhuis
Alice B. Chang
Delphine Chan-Seng
Ashutosh Chilkoti
Jennifer Collins
Xin-Xing Deng
Fu-Sheng Du
Harry M. Edenborn
Carlos Guerrero-Sanchez
Robert H. Grubbs
David M. Haddleton
Laura Hartmann
Joris J. Haven
Daisuke Hayata
Yusuke Hibi
Elisa Huerta
Geoffrey R. Hutchison
Masami Kamigaito
Ilana Y. Kanal
Daniel J. Keddie
Bert Klumperman
Jian Li
Zi-Chen Li
Steven R. Little
Jean-François Lutz
Akikazu Matsumoto
Anne J. McNeil
E. W. Meijer
Tara Y. Meyer
P. J. Milnes
Daniel A. Mitchell
Garret M. Miyake
Graeme Moad
Simone Mosca
Clément Mugemana
R. K. O'Reilly
Makoto Ouchi
Edmund F. Palermo
Anja R. A. Palmans
Daniela Ponader
Almar Postma
Caroline Proulx
Felipe García Quiroz
Ezio Rizzardo
Carine Robert
Valentin O. Rodionov
Sam N. Rothstein
Junji Sakamoto
Kotaro Satoh
Mitsuo Sawamoto
Thorsten Schwemmer
Olga Shishkan
Takamasa Soejima
Sansanee Srichan
Jing Sun
Takaya Terashima
San H. Thang
Christophe M. Thomas
Paul Wilson
Russell Wallis
Michael A. Washington
Sebastian Wieczorek
Ryan M. Weiss
Michael R. Whittaker
Patrick Wilke
Felix Wojcik
Per B. Zetterlund
Jian Zhang
Qiang Zhang
Ronald N. Zuckermann