Restorative Neurology of Spinal Cord Injury

Edited by Milan R. Dimitrijevic, Byron A. Kakulas, W. Barry McKay, and Gerta Vrbova

Promotes restorative neurology, which is based on the assessment of residual motor control after spinal cord injury
Describes how to apply restorative intervention in order to improve motor control
Imaginative and optimistic in its approach to spinal cord injury
Focuses on the spinal cord and its role in motor control

Restorative Neurology of Spinal Cord Injury

Edited by Milan R. Dimitrijevic, Byron A. Kakulas, W. Barry McKay, and Gerta Vrbova

Description

Following injury or disease, neural circuitry can be altered to varying degrees leading to highly individualized characteristics that may or may not resemble original function. In addition, lost or partially damaged circuits and the effects of biological recovery processes coupled with learned compensatory strategies create a new neuroanatomy with capabilities that are often not functional or may interfere with daily life. To date, the majority of approaches used to treat neurological dysfunction have focused on the replacement of lost or damaged function, usually through the suppression of surviving neural activity and the application of mechanical assistive devices. Restorative Neurology of Spinal Cord Injury offers a different and novel approach.

Focusing on the spinal cord and its role in motor control, the book details the clinical and neurophysiological assessment process and methods developed throughout the past half century by basic and clinical scientists. Then, through the use of specialized clinical and neurophysiological testing methods, conduction and processing performed within the surviving neural circuitry is examined and characterized in detail. Based on the results of such assessment, treatment strategies, also described in this book, are applied to augment, rather than replace, the performance of surviving neural circuitry and improve the functional capacity of people who have experienced injury to their spinal cords.

Restorative Neurology of Spinal Cord Injury

Edited by Milan R. Dimitrijevic, Byron A. Kakulas, W. Barry McKay, and Gerta Vrbova

Foreword

Preface

Chapter 1 - Residual motor function after spinal cord injury

Chapter 2 - Neurophysiological principles for the assessment of residual motor control below the spinal cord injury in humans

Chapter 3 - Restorative neurology of motor control after spinal cord injury: clinical practice

Chapter 4 - Neural control of locomotion

Chapter 5 - Summary of strategies used to repair the injured spinal cord

Chapter 6 - The reconstructive neurosurgery of spinal injury

Chapter 7 - Criteria for biological interventions for spinal cord injury

Chapter 8 - Neurophysiological assessment of human motor control and changes caused by spinal cord injury

Chapter 9 - Neurophysiologic monitoring of the human spinal cord functional integrity during surgical interventions

Chapter 10 - Transcutaneous lumbar posterior root stimulation for motor control studies and modification of motor activity after spinal cord injury

Epilogue

Appendix I - A manual for the neurophysiological assessment of motor control: The Brain Motor Control Assessment (BMCA) Protocolpages

Appendix II - Academic environment for the development of human motor control in Ljubljana

Restorative Neurology of Spinal Cord Injury

Edited by Milan R. Dimitrijevic, Byron A. Kakulas, W. Barry McKay, and Gerta Vrbova

Author Information

Milan R. Dimitrijevic, MD, PhD, Principle Investigator of Foundation for Movement Recovery, Oslo, Norway; Emeritus Professor, Baylor College of Medicine, Houston, TX.

Byron A. Kakulas, MD, FRACP, FRCPA, FRCPath, Medical Director, Australian Neuromuscular Research Institute, Nedlands, Western Australia, Australia.

W. Barry McKay, BS, Research Scientist, Norton Neuroscience Institute, Louisville, Kentucky.

Gerta Vrbová, PhD, Emeritus Professor, Division of Developmental. Neuroscience, University College London;
Visiting Professor, Royal Veterinary College, London, United Kingdom.

Contributors:

Nils G Andresen
Foundation for Movement Recovery
Oslo, Norway

Manfred Bijak, Ph.D.
Center for Medical Physics and Biomedical Engineering
Medical University Vienna
Vienna, Austria

Justin Brown, M.D.
Division of Neurosurgery
Center for Neurophysiology and Restorative Neurology
University of California at San Diego School of Medicine
San Diego, California, USA

Paulo Costa, M.D.
Department of Neurological, Neuropsychological, Morphological and Motor Sciences
University Hospital
Verona, Italy

Simon M. Danner, M.Sc.
Institute for Analysis and Scientific Computing
Vienna University of Technology
Vienna, Austria

Vedran Deletis, M.D., Ph.D.
Albert Einstein Colleague of Medicine
Institute for Neurology and Neurosurgery,
St. Luke's- Roosevelt Hospital
New York, N.Y., USA

Meta M. Dimitrijevic, M.D.
Foundation for Movement Recovery
Oslo, Norway

Milan R. Dimitrijevic, M.D., Ph.D.
Department of Physical Medicine and Rehabilitation
Baylor College of Medicine
Houston, Texas, USA
Foundation for Movement Recovery
Oslo, Norway

Ursula Hofstoetter, Ph.D.
Institute for Analysis and Scientific Computing
Vienna University of Technology
Center for Medical Physics and Biomedical Engineering
Medical University Vienna
Vienna, Austria

Byron A. Kakulas, M.D., F.R.A.C.P., F.R.C.P.A., F.R.C.Path.
Australian Neuromuscular Research Institute
Centre for Neuromuscular and Neurological Disorders
University of Western Australia
Perth. Western Australia

Henryk Majezynski, Ph.D., D.Sc.
Nencki Institute of Experimental Biology PAS
Department of Neurophysiology
Laboratory of Neuromuscular Plasticity
Warsaw, Poland

Winfried Mayr, Ph.D.
Center for Medical Physics and Biomedical Engineering
Medical University of Vienna
Vienna, Austria

W. Barry McKay, B.S.
Norton Neuroscience Institute
Louisville, Kentucky, USA

Karen Minassian, Ph.D.
Institute for Analysis and Scientific Computing
Vienna University of Technology
Center for Medical Physics and Biomedical Engineering
Medical University Vienna
Vienna, Austria

Frank Rattay, Ph.D.
Institute for Analysis and Scientific Computing
Vienna University of Technology
Vienna, Austria

Franscesco Sala, M.D.
Department of Neurological, Neuropsychological
Morphological and Motor Sciences
University Hospital
Verona, Italy

Arthur M. Sherwood, Ph.D.
Department of Physical Medicine and Rehabilitation
Baylor College of Medicine
Houston, Texas, USA

Urszula Slawinska, Ph.D., D.Sc.
Nencki Institute of Experimental Biology PAS
Department of Neurophysiology
Laboratory of Neuromuscular Plasticity
Warsaw, Poland

Simon F.T. Tang, M.D.
Department of Physical Medicine and Rehabilitation
Chang Gung Memorial Hospital
Chang Gung University
Taipei, Taiwan

Keith Tansey, M.D., Ph.D.
Director, Spinal Cord Injury Research
Crawford Research Institute, Shepherd Center
Departments of Neurology & Physiology
Emory University School of Medicine
Spinal Cord Injury Clinic
Atlanta Veterans Administration Medical Center
Atlanta, Georgia, USA

Gerta Vrbova, Ph.D.
Division of Developmental Neuroscience
University College
Royal Veterinary College
London, United Kingdom

Zvonka Zupanic Slavec, M.D., M.A., Ph.D.
Institute for the History of Medicine
Medical faculty, University of Ljubljana
Ljubljana, Slovenia

Restorative Neurology of Spinal Cord Injury

Edited by Milan R. Dimitrijevic, Byron A. Kakulas, W. Barry McKay, and Gerta Vrbova

Reviews and Awards

"Seabird Islands provides a solid first attempt at compiling available data in a sparse, but diverse, area of study... The volume is both an ideal go-to reference for natural resource managers and an excellent textbook for upperlevel students in conservation biology, macroecology, or resource management." -- Kate Ingenloff, Biodiversity Institute and Ecology & Evolutionary Biology, University of Kansas, Lawrence, Kansas