Overlapping Pain and Psychiatric Syndromes

Global Perspectives

Edited by Mario Incayawar and Sioui Maldonado Bouchard

A current and comprehensive review of the intersection between pain medicine and psychiatry
Incorporates illustrative case studies and practice recommendations throughout
Presents a cross-cultural approach to treating chronic pain and psychiatric comorbidities

Overlapping Pain and Psychiatric Syndromes

Global Perspectives

Edited by Mario Incayawar and Sioui Maldonado Bouchard

Description

Chronic pain seldom presents alone. Pain patients frequently have comorbid psychiatric conditions and those suffering from mental illness often experience pain. Nonetheless, pain conditions and psychiatric disorders have customarily been understood and treated as different and separate clinical entities, to the detriment of patients' wellbeing. This book will describe the complex and striking relationships between pain and psychiatric disorders, offering the first comprehensive review of the challenging and neglected intersection between pain medicine and psychiatry. Written by world-renowned experts in the fields of pain and psychiatry, chapters contribute a valuable array of clinical and theoretical perspectives and include illustrative case examples throughout.

Overlapping Pain and Psychiatric Syndromes

Global Perspectives

Edited by Mario Incayawar and Sioui Maldonado Bouchard

FOREWORD
Ron Wintrob
PREFACE
Mario Incayawar
THE NATURE OF PAIN & PSYCHIATRIC COMORBIDITY
1. The Need to Fathom the Overlapping Pain and Psychiatric Syndromes
Mario Incayawar
2. Recognizing the Co-occurrence of Chronic Pain and Mental Illness
Jan Jaracz
3. Glial Cells and Pro-inflammatory Cytokines as Shared Neurobiological Bases for Chronic Pain and Psychiatric Disorders
Judith A. Strong, Sang Won Jeon, Jun-Ming Zhang, and Yong-Ku Kim
4. Shared Brain Synaptic Mechanisms of Pain and Anxiety: Insight from Preclinical Studies
Ipek Yalcin and Min Zhuo
5. The Epigenetic Bridge between Stress, Chronic Pain, and Psychiatric Disorders
Sioui Maldonado-Bouchard and Mario Incayawar
DIAGNOSTIC ISSUES
6. Identifying and Assessing Overlapping Chronic Pain and Mental Illness
Glenn J. Treisman
7. Assessment and Monitoring of Patients with Chronic Pain and Co-Occurring Substance Use and Abuse
Jon Streltzer
8. Psychometrics for Detecting Pain-Related Malingering
Blake H. Tearnan
9. Neuroimaging Correlates for Psychological and Chronic Pain Experiences
John A. Sturgeon and Katherine T. Martucci
PAIN SYNDROMES AND PSYCHIATRIC COMORBIDITIES
10. Navigating the Pain and Suicide Conundrum
Martin D. Cheatle, Simmie Foster, and Nicole Tang
11. Depression and Anxiety as Risk Factors for Temporomandibular Joint Disorder - A German Perspective
Stefan Kindler and Marike Bredow-Zeden
12. Recognizing the Psychiatric Burden of Anxiety and Depression in Children with Headache, Chest, and Abdominal Pain
Susan T. Tran, Ana B. Goya Arce, and Anjana Jagpal
13. Exploring Pain Conditions in Schizophrenia and Bipolar Disorder
Mael Gagnon-Mailhot; Janie Damien; Vincent Pelland; and Serge Marchand
14. Posttraumatic Stress Disorder and Chronic Pain in the Military
Renée El-Gabalawy, Pamela L. Holens, Jordana Sommer, and Rachel Roy.
15. The Clinical Neuroscience of the Insomnia-Fibromyalgia Link: An Overview for Clinicians
Christina S. McCrae, Ashley Curtis, and Daniel B. Kay
16. Alcohol and Chronic Pain: Shared Neural Circuits and Clinical Features
Tessa Frohe, Benjamin Berey, Katie Witkiewitz, Elizabeth McCallion, and Kevin E. Vowles
17. Catastrophizing in Comorbid Chronic Pain and Mental Illness: A Primer for Clinicians
Cynthia Townsend and Donald Townsend
18. Untangling Comorbid Irritable Bowel Syndrome and Psychiatric Disorders
Mihaela Fadgyas Stanculete and Dan L. Dumitrascu
19. The Many Faces of Chronic Urogenital Pain: Vulvodynia and Psychiatric Comorbidities
Bernard L. Harlow, Miriam J. Haviland, and Sophie Bergeron
20. Understanding and Managing Personality Disorders in Chronic Pain
James N. Weisberg, Channing Twyner, and Christopher Paul
21. Pain and Comorbid Psychiatric Illnesses in the Elderly: A Fitful Marriage and Its Management
Mellar P. Davis and John Shuster Jr.
22. Does Self-injury Hurt? Understanding the Experience and Potential Functions of Pain in Self-injury
Amy Kranzler, Kara B. Fehling, Julia Brillante, and Edward A. Selby
TREATMENT STRATEGIES
23. Innovative Management of Chronic Pain and Psychiatric Comorbidities
J. Gregory Hobelmann and Michael R. Clark
24. Acknowledging the Clinical Effects of Words in Pain Medicine and Psychiatry
Lise Bouchard and Mario Incayawar
25. Detecting and Managing the Untreated Pain in Dementia
Anne Corbett
26. Effective Management of Pain in Autism Spectrum Disorders and Intellectual Disability
Djea Saravane
PAIN MEDICINE, PSYCHIATRY, AND SOCIETY
27. Cultural Spectrum of Chronic Pain and Somatization Syndromes: Indian Experiences
Geetha Desai, Santosh K. Chaturvedi, and Dinesh Bhugra
28. Jaki, a Puzzling Inca Syndrome of Comorbid Pain and Mental Illness
Mario Incayawar
29. Taming Artificial Intelligence in Psychiatry and Pain Medicine- Promises and Challenges
Usef Faghihi, Sioui Maldonado-Bouchard, Mario Incayawar

Overlapping Pain and Psychiatric Syndromes

Global Perspectives

Edited by Mario Incayawar and Sioui Maldonado Bouchard

Author Information

Edited by Mario Incayawar, Director, Runajambi Institute, Runajambi Institute, and Edited by Sioui Maldonado Bouchard

MARIO INCAYAWAR, MD, MSC, PHD, is a physician-scientist, educator, and published author specializing in psychiatry and pain medicine. A recipient of the Guggenheim Fellowship in 2006, he has held the Henry R. Luce Professorship in Culture, Brain, Mind, and Medicine at the Claremont Colleges; and the William F. Quillian Jr. International Professorship, at R-MWC, Virginia. He was elected to the Executive Committee of the Transcultural Psychiatry Section of the World Psychiatric Association from 2005 to 2011 and is the founder and director of the Runajambi Institute. www.runajambi.org/incayawar SIOUI MALDONADO BOUCHARD, MSC, PHD, is a neuroscientist specializing in behavioral neuroscience and psychology. She has conducted research about the impact of the social environment on spinal cord injury and the association between the social environment and pain. The translation of scientific knowledge to the larger medical community and beyond is particularly important to her. A former post-doctoral

fellow at the Pain Genetics Laboratory at McGill University, she has contributed several papers in Canadian and American journals for the medical community.

Contributors:

Benjamin Berey, BA
Doctoral Research Assistant
University of Florida
Gainesville, FL

Sophie Bergeron, PhD
Full Professor
Department of Psychology
Université de Montréal
Montréal, Canada

Dinesh Bhugra, MA, MSc, MBBS, FRCPsych, MPhil, PhD
Professor of Mental Health and Cultural Diversity
Institute of Psychiatry
King's College London
London, UK

Lise Bouchard, MA, PhD
Director of Research
Runajambi Institute
Québec, Canada

Marike Bredow-Zeden, DMD
Department of Oral and Maxillofacial Surgery/Plastic Surgery
University of Greifswald
Greifswald, Germany

Julia Brillante, PsyM
Graduate Student
Rutgers, The State University of New Jersey
Graduate School of Applied and Professional Psychology
New Brunswick, NJ

Santosh K. Chaturvedi, MD, FRCPsych
Dean, Behavioural Sciences and Professor of Psychiatry
National Institute of Mental Health and Neurosciences
Head, Department of Mental Health Education
Bangalore, India

Martin D. Cheatle, PhD
Associate Professor
Department of Psychiatry
Perelman School of Medicine, University of Pennsylvania
Philadelphia, PA

Michael R. Clark, MD, MPH, MBA
Vice Chair, Clinical Affairs
Director, Pain Treatment Program
Johns Hopkins University School of Medicine
Baltimore, MD

Anne Corbett, BSc, MRes, PhD
Senior Lecturer in Dementia Research
Exeter University
Exeter, UK

Ashley F. Curtis, PhD
Postdoctoral Fellow
Department of Psychiatry
University of Missouri
Columbia, MO

Janie Damien, BSc
Graduate Student
Université de Sherbrooke
Québec, Canada

Mellar P. Davis, MD, FCCP, FAAHPM
Director of Palliative Services
Geisinger Medical Center
Danville, PA

Geetha Desai, MD, DNB, PhD
Additional Professor
Department of Psychiatry
National Institute of Mental Health and Neuro Sciences (NIMHANS)
Bengaluru, India

Dan L. Dumitrascu, MD, AGAF, RFF
Professor
Iuliu Hatieganu University of Medicine and Pharmacy
Cluj-Napoca, Romania

Renée El-Gabalawy, MA, PhD
Assistant Professor
Departments of Anesthesiology, Perioperative and Pain Medicine
Clinical Health Psychology, University of Manitoba
Staff Psychologist, Winnipeg Regional Health Authority
University of Manitoba
Manitoba, Canada

Usef Faghihi, PhD
Assistant Professor
Department of Mathematics and Computer Science
Université du Québec à Trois-Rivières
Québec, Canada

Kara B. Fehling, MS
Graduate Student
Rutgers, The State University of New Jersey
New Brunswick, NJ

Simmie L. Foster, MD, PhD
Depression Clinical Research Program
Department of Psychiatry
Massachusetts General Hospital
Harvard Medical School
Boston, MA

Tessa M. Frohe, BA
Doctoral Research Assistant
University of Florida
Gainesville, FL

Maël Gagnon-Maihot, BA
Research Assistant
Health and Well-Being Lab
Bishop's University
Quebec, Canada

Ana B. Goya Arce, PhD
Post-Doctoral Fellow
Department Anesthesia
Stanford University
Santa Clara, CA

Bernard L. Harlow, MPH, PhD
Professor of Epidemiology
Department of Epidemiology
Boston University School of Public Health
Boston, MA

Miriam J. Haviland, MSPH
Doctoral Student, Epidemiology
Department of Epidemiology
Boston University School of Public Health
Boston, MA

J. Gregory Hobelmann, MD, MPH
Chief Medical and Clinical Officer
Ashely Addiction Treatment
Adjunct Faculty, Johns Hopkins Department of Psychiatry and Behavioral Sciences
Baltimore, MD

Pamela L. Holens, MEd, MA, PhD
Assistant Professor, Department of Clinical Health Psychology
Clinical Director and Psychologist, Winnipeg Operational Stress Injury Clinic
University of Manitoba
Manitoba, Canada

Mario Incayawar, MD, MSc, DESS, PhD
Director, Runajambi Institute
Quichua (Inca) Nation
Medical Director, Cross-Cultural Clinic for Pain and Psychiatry
Former Henry R. Luce, Professor in Brain, Mind and Medicine: Cross-Cultural Perspectives
Pitzer, Claremont McKenna, and Harvey Mudd Colleges
Claremont, CA

Anjana Jagpal, MA
Graduate Assistant
Department of Psychology
DePaul University
Chicago, IL

Jan Jaracz, MD, PhD
Associate Professor
Department of Adult Psychiatry
Pozna? University of Medical Sciences
Pozna?, Poland

Sang Won Jeon, MD
Clinical Associate Professor
Department of Psychiatry
College of Medicine
Korea University, Ansan Hospital
Ansan, Republic of Korea

Daniel B. Kay, PhD
Assistant Professor
Clinical Psychology
Brigham Young University
Provo, UT

Yong-Ku Kim, MD, PhD
Professor
Department of Psychiatry
College of Medicine
Korea University
Seoul, Korea

Stefan Kindler, MD, DDS
Consultant
Department of Oral and Maxillofacial Surgery/Plastic Surgery
University of Greifswald
Greifswald, Germany

Amy Kranzler, PhD
Clinical Postdoctoral Fellow
Columbia University Medical Center
New York, NY

Sioui Maldonado-Bouchard, MSc, PhD
Medical Student, Université de Montréal School of Medicine
Fellow, Pain Genetics Laboratory, McGill University
Montreal, Quebec, Canada
Research Associate
Runajambi Institute
Quichua (Inca) Nation

Serge Marchand, PhD
Scientific Director, Professor, Investigator
FRQS, Université de Sherbrooke, Centre de recherche du CHUS
Québec, Canada

Katherine T. Martucci, PhD
Assistant Professor
Center for Translational Pain Medicine
Department of Anesthesiology
Duke University School of Medicine
Durham, NC

Elizabeth A. McCallion, MS
Graduate Student/Psychology Intern
University of New Mexico/VA Palo Alto Health Care System
Albuquerque, NM

Christina S. McCrae, PhD
Director, MizZzou Sleep Research Lab
Professor, Department of Psychiatry, School of Medicine
University of Missouri
Columbia, MO

Christopher Paul, MD
Assistant Professor
Department of Anesthesiology
University of Arkansas for Medical Sciences
Little Rock, AR

Vincent Pelland, MD
Resident, Family Medicine
Centre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke (CIUSSS de l'Estrie-CHUS)
Québec, Canada

Rachel Roy, BA (Hons)
Research Coordinator for Clinical Research Network within SPOR Chronic Pain Network
University of Manitoba
Manitoba, Canada

Djea Saravane, MD, MSc, PhD
Head of Integrated Medicine and Pain Clinic in Mental Health, Autistic Spectrum Disorders, Polyhandicap and Rare Genetic Handicap
Advisor, Vesalius Foundation
Barthelemy Hospital-Etampes
Essonne, France

Edward A. Selby, PhD
Assistant Professor
Department of Psychology
Rutgers, The State University of New Jersey
New Brunswick, NJ

John L. Shuster, Jr., MD, FAPM
Psychiatrist, VA Tennessee Valley Health System
Clinical Professor of Psychiatry, Vanderbilt University Medical Center
Nashville, TN

Jordana L. Sommer, BA (Hons)
Graduate Student, Department of Psychology
Research Associate, Department of Anesthesiology, Perioperative and Pain Medicine
University of Manitoba
Manitoba, Canada

Mihaela Fadgyas Stanculete, MD, MSc, PhD
Senior Lecturer
Department of Neuroscience, Psychiatry
Iuliu Hatieganu University of Medicine and Pharmacy
Cluj-Napoca, Romania

Jon Streltzer, MD
Professor Emeritus of Psychiatry
John A. Burns School of Medicine
University of Hawaii
Honolulu, HI

Judith A. Strong, PhD
Research Associate Professor
Department of Anesthesiology
University of Cincinnati College of Medicine
Cincinnati, OH

John A. Sturgeon, PhD
Assistant Professor
Department of Anesthesiology and Pain Medicine
University of Washington School of Medicine
Seattle, WA

Nicole K. Y. Tang, DPhil, CPsychol
Associate Professor, Department of Psychology
Director, Warwick Sleep and Pain Lab
University of Warwick
Coventry, UK

Blake H. Tearnan, PhD
Renown Medical Center Rehabilitation Hospital
Reno, NV

Cynthia O. Townsend, PhD, ABPP
Clinical Director, Pain Rehabilitation Center
Assistant Professor, Department of Psychology
Mayo Clinic
Phoenix, AZ

Donald R. Townsend, PhD, DBSM
Sleep Psychologist
Diplomate American Board of Sleep Medicine
Founder, Insomnia Expertz, PLLC
Phoenix, AZ

Susan T. Tran, PhD
Assistant Professor
Department of Psychology
DePaul University
Chicago, IL

Glenn J. Treisman, MD, PhD
Eugene Meyer III Professor of Psychiatry and Medicine
Department of Psychiatry and Behavioral Sciences
Johns Hopkins Hospital
Baltimore, MD

Channing Twyner, MD
Assistant Professor
Department of Anesthesiology
University of Mississippi Medical Center
Jackson, MS

Kevin E. Vowles, PhD
Associate Professor
Department of Psychology
University of New Mexico
Albuquerque, NM

James N. Weisberg, PhD
Associate Professor of Anesthesiology and Perioperative Medicine
University of Alabama-Birmingham
Birmingham, AL

Ronald Wintrob, MD
Former Chair, World Psychiatric Association-TPS
Clinical Professor of Psychiatry and Human Behavior
Brown University
Providence, RI

Katie Witkiewitz, PhD
Associate Professor
Department of Psychology
University of New Mexico
Albuquerque, NM

Ipek Yalcin, PhD, PharmD
Associate Professor
Institut des Neurosciences Cellulaires et Intégratives
Centre National de la Recherche Scientifique and
Université de Strasbourg
Strasbourg, France

Jun-Ming Zhang, MD, MSc
Professor and Vice Chair for Research
Department of Anesthesiology
University of Cincinnati College of Medicine
Cincinnati, OH

Min Zhuo, PhD
Professor
Department of Physiology
University of Toronto
Ontario, Canada