Molecular Diagnostics

Edited by Anthony Warford and Nadège Presneau

Fundamentals of Biomedical Science

A blend of science theory and biomedical science practice make this series ideal for those seeking both the knowledge and skills to become proficient Biomedical Scientists.
Case studies enrich the text and emphasise clinical relevance.
Self-test and discussion questions, with answers provided online, encourage students to analyze the text and develop their problem solving skills.

Molecular Diagnostics

Edited by Anthony Warford and Nadège Presneau

Fundamentals of Biomedical Science

Description

One of the most notable trends in biomedical science in recent years has been the increasing use of molecular techniques as part of the diagnosis of disease. As such, there is a growing need for students to understand the technological basis of molecular analysis and to have a comprehensive appreciation of their use in diagnosis. Combining coverage of molecular techniques with their application to diagnostic pathology, this book provides students with a thorough and up to date appreciation of the scope of molecular analysis, the principles of the technology used, and thematic diagnostic application.

As part of the Fundamentals of Biomedical Science series, the book provides a unique blend of theory and practice, featuring a range of learning features to help students assimilate the information presented quickly and effectively. It will be relevant to undergraduate students on a wide variety of biomedical pathways, cutting across traditional discipline boundaries to provide a unified overview of molecular diagnostics.

Molecular Diagnostics

Edited by Anthony Warford and Nadège Presneau

Fundamentals of Biomedical Science

Introduction, Anthony Warford and Nadège Presneau
1:Sample preparation, Anthony Warford and Sandra Hing
2:The molecular laboratory, Sandra Hing and Anthony Warford
3:Intact sample analysis, Anthony Warford and Emanuela V Volpi
4:Homogenate sample analysis, Nadège Presneau, Abdul Hye, and Nicholas Ashton
5:Sequencing technologies, Nadège Presneau and Rifat Hamoudi
6:Molecular analysis and interpreting molecular data, Rifat Hamoudi and Anthony Warford
7:Recent technical advances in molecular analysis, Nadège Presneau and Mary Alikian
8:Haemopoietic diseases 1 - leukaemias, Georgina Ryland and Piers Blombery
9:Haemopoietic diseases 2 - lymphoproliferative disorders, Mark Catherwood and Ken Mills
10:Breast cancer, Mary Falzon, Elaine Borg, and Alexandra Saetta
11:Epithelial tumours and melanoma, Manuel Rodriguez-Justo
12:Mesenchymal tumours, Fernanda Amary
13:Pre-natal and neo-natal testing, Claire V.S. Brasted-Pike

Molecular Diagnostics

Edited by Anthony Warford and Nadège Presneau

Fundamentals of Biomedical Science

Author Information

Edited by Anthony Warford, Emeritus Fellow, Department of Biomedical Sciences, University of Westminster, and Nadège Presneau, Senior Lecturer in Biomedical Sciences, University of Westminster

Anthony Warford is Emeritus Fellow in the Department of Biomedical Sciences at the University of Westminster, Fellow of the Institute of Biomedical Sciences, and Chartered Scientist. He is the primary author of two scientific papers on tissue microarray, two reviews on in situ hybridisation, and a book chapter on same subject, as well as being a co-author of many other papers. He has lectured internationally on immunohistochemistry and in situ hybridisation.

Nadège Presneau is Senior Lecturer in the Department of Biomedical Sciences at the University of Westminster. She teaches Molecular Pathology and Cancer Genetics/Genomics at undergraduate and postgraduate levels. Her research focuses principally on developing new bioinformatics approaches to identify driver genes involved in breast cancer using high throughput technologies such as Next Generation Sequencing. She is also interested in the development of new diagnostic tools for cancer as well as biobanking and ethics in translational research.

Contributors:

Mary Alikian
Honorary Research Associate
Department of Medicine, Centre for Haematology, Imperial College London, UK

Fernanda Amary
Consultant Histopathologist and Clinical Lead for Molecular Pathology
Royal National Orthopaedic Hospital, London, UK

Nicholas Ashton
Post-doctoral Scientist
Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg, Sweden

Piers Blombery
Consultant Haematologist
Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

Elaine Borg
Consultant Histopathologist and Cytopathologist
University College London Hospitals, UK

Claire VS Brasted-Pike
Deputy Head of Department
Biomedical and Forensic Science, Anglia Ruskin University, Cambridge, UK

Mark A Catherwood
Clinical Scientist
Molecular Haematology, Belfast City Hospital, UK

Mary Falzon
Consultant Histopathologist and Cytopathologist
University College London Hospitals, UK

Rifat Hamoudi
Associate Professor
College of Medicine, Department of Clinical Sciences, University of Sharjah, United Arab Emirates

Sandra Hing
Senior Laboratory Advisor
Genomics Implementation Unit, 100,000 Genomes Project, NHS England, London, UK

Abdul Hye
Post-doctoral Research Worker, Department of Old Age Psychiatry, Kings College London, UK

Ken Mills
Professor
School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, UK

Nadège Presneau
Senior Lecturer in Biomedical Sciences
University of Westminster, UK

Manuel Rodriguez-Justo
Consultant Pathologist
University College London Hospitals, UK

Georgina L Ryland
Postdoctoral Research Officer, Molecular Haematology
Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

Alexandra Saetta
Junior Doctor
Bart's and The London School of Medicine and Dentistry, London, UK

Emanuela V. Volpi
Reader in Biomedical Science
University of Westminster, London, UK

Anthony Warford
Emeritus Fellow, Biomedical Sciences
University of Westminster, London, UK