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Published: 06 November 2020 (Estimated)

1,056 Pages


ISBN: 9780198788652

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This text is published by OUP Higher Education Division

New Edition

Molecular Biology

Principles of Genome Function

Third Edition

Nancy Craig, Rachel Green, Carol Greider, Gisela Storz, and Cynthia Wolberger

  • A focus on the underlying principles equips students with a robust conceptual framework on which to add further detail from the vast amount of scientific information available to us today
  • An emphasis on commonalities reflects the conserved molecular processes and components that we now know to exist between bacteria, archaea and eukaryotes
  • Experimental Approach panels demonstrate the central importance of experimental evidence to furthering our understanding of molecular biology by describing research that has been particularly valuable in elucidating different aspects of the subject
  • Online resources, for both instructors and students alike, enhance the educational value of the text
  • Also available as an e-book with functionality, navigation features, and links that offer extra learning support

New to this Edition:

  • New content on epigenetics, targeted genome editing and pre-mRNA splicing
  • Cutting-edge scientific breakthroughs in CRISPR technology, including a description of newly defined steps in the molecular mechanisms underlying CRISPR-mediated adaptation in bacterial adaptive immunity; and a description of a recently discovered transposable element family whose integration mechanism is closely related to and involves molecular relatives of the CRISPR-Cas bacterial adaptive immunity system
  • Enhanced coverage of DNA replication and regulatory RNAs
  • Seven new Experimental Approach panels

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