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Published: 27 October 2005

344 Pages | 2 halftones, 41 line illus.

6-1/8 x 9-1/4 inches

ISBN: 9780195174328

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Bookseller Code (05)

Mental Retardation and Developmental Delay

Genetic and Epigenetic Factors

Moyra Smith, M.D.

Oxford Monographs on Medical Genetics

This book makes readily available current knowledge on the subject of mental retardation and developmental delay and applies it to clinical medicine, providing information essential to neurologists, geneticists, physicians and pediatricians as they search for the causes of mental handicap in their patients. Chapters cover normal and abnormal brain structure, neurogenesis, and signal transduction before delving into a discussion of both the environmental factors that may lead to neurocognitive deficits and the cytogenetic, biochemical and molecular defects specifically associated with mental retardation. The text concludes with a clinically practical discussion of carrier detection, presymptomatic diagnosis, and treatment of various genetic diseases.

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