Malignant Pleural Mesothelioma

Edited by Kenneth O'Byrne and Valerie Rusch

This book is extremely timely given the increasing importance and prevalence of the disease
The instance of malignant pleural mesothelioma is not expected to reach its peak until 2020 so a comprehensive, evidence-based book on the subject is needed
Mesothelioma is an active area of research as physicians are becoming more aware of the problem

Malignant Pleural Mesothelioma

Edited by Kenneth O'Byrne and Valerie Rusch

Description

This book provides health professionals and scientists with a comprehensive overview of the mesothelioma - an asbestos induced malignancy. It includes chapters on epidemology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, and radiotherapy as well as the molecular biology and future therapies.

Malignant Pleural Mesothelioma

Edited by Kenneth O'Byrne and Valerie Rusch

Section 1. Clinical Features of Mesothelioma
1. The Epidemiology and Aetiology of Malignant Mesothelioma, Juliet E King & Philip S Hasleton
2. Epidemiological Snapshots From Around the World, AW Musk, NH de Klerk, Jacek Niklinski, Wieslawa Niklinska, Elzbieta Chyczewska, Jerzy Laudanski, Wojciech Naumnik, Lech Chyczewski, Eric Pluygers, Raymond P Abratt, Daniel A Vorobiof, Neil White, Salih Emri, Murat Tuncer & Izzettin Baris
3. Clinical Presentation, Radiological Evaluation and Diagnosis, Michael D Peake & James Entwisle & Steven Gray
4. Histopathology of Malignant Pleural Mesothelioma, Juliet King, Françoise Galateau-Sallé & Philip Hasleton
5. Clinico-Pathological Prognostic Factors & Scoring Systems in Malignant Pleural Mesothelioma, J.A Burgers & J.P.J.J Hegmans
Section 2. Biology of Mesothelioma
6. Carcinogenic Mechanisms in Mesothelioma: Effects of asbestos on cell signal events, transcription factors, and inflammatory cytokines, BT Mossman & William Swain
7. Viral Factors in the Pathogenesis of Malignant Mesothelioma, Amy Powers, Maurizio Bocchetta & Michele Carbone
8. Growth Factors, Cyclooxygenease-2 and Matrix Metalloproteinases in Malignant Mesothelioma, John G Edwards, Uwe Zangemeister-Wittke & Kenneth J O'Byrne
9. Vascularisation in Malignant Mesothelioma, Peter B Vermeulen, Roberto Salgado & Eric A Van Marck
10. Immunobiology of Malignant Mesothelioma, AM Smith, S Lansley, C Jackaman, B Koloska, S Broomfield, Bruce W.S Robinson & D.J Nelson
11. Cytogenetic and Molecular Genetic Changes in Malignant Mesothelioma, Deborah A Altomare & Joseph R Testa
Section 3. Treatment Strategies
12. The Role of Surgery for Diagnosis, Staging and Symptom Control in Malignant Pleural Mesothelioma, David A Waller & Antonio E Martin-Ucar
13. Surgical and Multimodality Approaches to the Management of Operable Malignant Mesothelioma, Daniel J Boffa & Valerie W Rusch
14. Systemic Chemotherapy for Malignant Pleural Mesothelioma, Jeremy P.C Steele & Robin M Rudd
15. Radiotherapy for Mesothelioma, Craig W Stevens, Kenneth M Forster & W. Roy Smythe
16. Immunotherapy for Malignant Mesothelioma, Mary ER O'Brien, Ander Urruticoechea Ribate & Bernard Souberbielle
17. Intra-thoracic Photodynamic Diagnosis and Treatment with Photodynamic Therapy or Hyperthermia of Malignant Mesothelioma, Paul Baas
18. Novel Therapies for Mesothelioma, Fiona Blackhall, Sofia Baka, Sarah Danson and Malcolm Ranson
19. Gene Therapy for Malignant Pleural Mesothelioma, Daniel H Sterman & Peter A DeLong
20. Palliative Care for Mesothelioma, Sam Ahmedzai & Helen Clayson
21. The Treatment of Mesothelioma Cases in the American and United Kingdom Legal Systems, Adrian Budgeon & John Ned Lipsitz

Malignant Pleural Mesothelioma

Edited by Kenneth O'Byrne and Valerie Rusch

Author Information

Dr Ken O'Byrne is President of the British Mesothelioma Trust. Professor Valerie Rusch, M.D. is currently Chief of Thoracic Surgery at Memorial Sloan-Kettering Cancer Center, where she also holds the William G. Cahan Chair. She is a member of the Editorial Boards for The Journal of Thoracic and Cardiovascular Surgery, The Journal of Clinical Oncology, The Oncologist, and Lung Cancer.

Malignant Pleural Mesothelioma

Edited by Kenneth O'Byrne and Valerie Rusch

Reviews and Awards

"Anybody dealing with diffuse malignant mesothelioma, in either a research or clincial setting, should learn a great deal from this book in topics outside his or her own immediate specializations. As this clinically relentless disease continues to increase but has proven so refractory to therapy, any additional knowledge is welcome ideed, and this book is also welcome indeed."--Respiratory Care

"A comprehensive overview of the subject, aimed at all health care professionals who come into contact with patients with the disease."--Anticancer Research