Journals Higher Education



Published: 25 March 2004

460 Pages | 10 color plates, 36 halftones & line illus.

ISBN: 9780198508786

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Bookseller Code (05)

Lysosomal Disorders of the Brain

Recent Advances in Molecular and Cellular Pathogenesis and Treatment

Frances M. Platt and Steven U. Walkley

Problems with cellular lysosome function underlie a group of neurological disorders known as the storage diseases. These are inherited disorders, characterized by a failure to control the accumulation of internal cell products resulting in cell death. In recent years major advances in the fields of biochemistry and cell biology have expanded our understanding of these disorders. This book describes the molecular mechanisms and pathophysiological pathways involved and the potential for interventions aimed at treatment.


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