Long-Term Outcomes in Psychopathology Research

Rethinking the Scientific Agenda

Edited by Evelyn J Bromet

American Psychopathological Association

Covers findings from long-term psychopathology outcome studies, problematic case definitions, and research priorities for patients with chronic and severe disorders
Contains chapters on cutting edge biological research that should be integrated into long-term outcome studies.
Emphasizes the importance of a bottom-up approach to learning from study populations rather than a top-down approach to believing we know what's important to learn and to measure.
Expands the outcomes research community beyond the boundaries of specific disorders.
Emphasizes the integration of personal narratives with pre-formulated question and response research

Long-Term Outcomes in Psychopathology Research

Rethinking the Scientific Agenda

Edited by Evelyn J Bromet

American Psychopathological Association

Description

Based on the 103rd annual meeting of the American Psychopathological Association, Long-Term Outcomes in Psychopathology Research: Rethinking the Scientific Agenda explores the long-term course of illness and functioning of individuals treated for mental health and substance use disorders and the outcomes research derived from these cases. Sections cover topics including: findings from long-term psychopathology outcome studies, problematic case definitions, differing perspectives on the concept of recovery, the need for continued long-term outcomes research, and research priorities for patients with chronic and severe disorders. The book employs the experiences of innovative mental health providers, reflecting the value of personal narratives in research conducted in cross-sectional increments with pre-formulated questions and response options. As psychiatry continues to refine its diagnostic categories and psychology demands greater attention to dimensionality, the need for interdisciplinary long-term studies is as critical as ever. This final volume in the American Psychopathological Association Series reflects on developments in outcomes research conducted in parallel with different disorders and offers suggestions for preserving long-term outcome studies as the mainstay of clinical knowledge.

Long-Term Outcomes in Psychopathology Research

Rethinking the Scientific Agenda

Edited by Evelyn J Bromet

American Psychopathological Association

Part I FINDINGS FROM LONG-TERM OUTCOME STUDIES

1. Past and Future Directions in Psychosis Research
EVELYN J. BROMET

2. Course of Bipolar Disorder in Adults and Children
KATHLEEN RIES MERIKANGAS, NICOLE JAMESON, AND MAURICIO TOHEN

3. Can Course Help Reduce the Heterogeneity of Depressive Disorders?
DANIEL N KLEIN

4. The Course of Substance Use Disorders: Trajectories, Endpoints, and Predictors
CHRISTINE TIMKO, RUDOLF H. MOOS, AND JOHN W. FINNEY

5. Commentary: Divergent Views on Heterogeneity in Long-Term Course and Outcome of Adult Mental and Substance Disorders
RAMIN MOJTABAI

Part 2 ONGOING DEBATES ABOUT CASE DEFINITIONS: DIAGNOSTIC BOUNDARY ISSUES

6. Using Developmental Trajectories to Validate Diagnostic Categories: Comparing and Contrasting Asperger's Syndrome and Autism
PETER SZATMARI

7. Disruptive Mood Dysregulation Disorder: The Result of a Problem Looking for a Diagnosis
GABRIELLE A. CARLSON

8. Deconstructing PTSD
MATTHEW A. FRIEDMAN

9. The Quantitative Classification of Mental Illness: Emerging Solution to Boundary Problems
ROMAN KOTOV

Part 3 DIFFERING PERSPECTIVES ON THE CONCEPT OF RECOVERY

10. Long-term Outcomes of Juvenile-Onset Depression: Is Recovery a Viable Concept?
MARIA KOVACS

11. Long-term Trajectories and Recovery from PTSD
ZAHAVA SOLOMON, AVIGAL SNIR, HENRY FINGERHUT, AND MICHAL ROSENBERG

12. Preventive Strategies to Optimize Recovery In Psychosis
PATRICK MCGORRY AND SHERILYN GOLDSTONE

13. Advocacy, Stigma, and Self-Disclosure: A Personal Perspective
FREDERICK J. FRESE

14. Organizational Change towards Recovery Oriented Service Provision: A Provider's Perspective
EDYE SCHWARTZ; INTRODUCTION BY LISA DIXON

Part 4 THE NEED FOR CONTINUED LONG-TERM OUTCOMES RESEARCH

15. Nonsuicidal Self-Injury: Old Problem, New Disorder, Limited Data
CATHERINE R. GLENN, ADAM C. JAROSZEWSKI, ALEXANDER J. MILLNER, JACLYN C. KEARNS, AND MATTHEW K. NOCK

16. Blending Technological Innovations into Long-Term Prospective Research
CARLOS N. PATO, JANET L. SOBELL, MICHELE T. PATO

17. Functional Magnetic Resonance Imaging (fMRI) of PTSD: Current Status and Future Directions
EREL SHVIL, KATHARINE REINER VAN DER HOORN, SANTIAGO PAPINI, GREGORY M. SULLIVAN, AND YUVAL NERIA

Part 5 EPILOGUE

18. Epilogue - Reconsidering Outcome Priorities for Serious Mental Illnesses
ROBERT B. ZIPURSKY

Long-Term Outcomes in Psychopathology Research

Rethinking the Scientific Agenda

Edited by Evelyn J Bromet

American Psychopathological Association

Author Information

Dr. Evelyn J. Bromet is Distinguished Professor of Psychiatry and Preventive Medicine at Stony Brook University. She received her BA in history from Smith College, PhD in epidemiology from Yale University, and postdoctoral training at Stanford's Social Ecology Laboratory. She founded the Psychiatric Epidemiology Training Program at the University of Pittsburgh where she did research on the aftermath of the Three Mile Island accident and the neuropsychiatric effects of workplace exposures. At Stony Brook, she is the architect of the Suffolk County Mental Health Project, now in its 20th year of follow-up, and conducted longitudinal studies of Chernobyl evacuees and clean-up workers in Ukraine along with a national prevalence study. Her current research also focuses on mental-physical comorbidity among responders to the World Trade Center disaster.

Contributors:

Gabrielle Carlson, MD
Department of Psychiatry
Stony Brook University
Stony Brook, NY

Lisa Dixon, MD, MPH
Professor of Psychiatry
Columbia University
New York State Psychiatric Institute
New York, NY

Henry Fingerhut, BS
The Bob Shapell School of Social Work
Tel Aviv University
Tel Aviv, Israel

John W. Finney, PhD
Department of Veterans Affairs Health Care System
Stanford University
Palo Alto, CA

Fred Frese, PhD
Northeast Ohio Medical University
Case Western Reserve University
The Summit County Recovery Project
Cleveland, OH

Matthew Friedman, MD, PhD
Departments of Psychiatry and Pharmacology & Toxicology
Geisel School of Medicine at Dartmouth
National Center for PTSD
White River Junction, NH

Catherine R Glenn, PhD
Department of Psychology
Harvard University
Cambridge, MA

Sherilyn Goldstone, PhD
Orygen Youth Health Research Centre
Centre for Excellence in Youth Mental Health
Department of Psychiatry
University of Melbourne
Melbourne, Australia

James Hudziak, MD
Vermont Center for Children, Youth and Families
University of Vermont
Burlington, VT

Adam C. Jaroszewski, BA
Department of Psychology
Harvard University
Cambridge, MA

Jaclyn C. Kearns, BA
Department of Psychology
Harvard University
Cambridge, MA

Daniel Klein, PhD
Departments of Psychology & Psychiatry
Stony Brook University
Stony Brook, NY

Nicole Jameson, BS
Genetic Epidemiology Branch
Intramural Research Program
National Institute of Mental Health
Bethesda, MD

Roman Kotov, PhD
Departments of Psychiatry & Psychology
Stony Brook University
Stony Brook, NY

Maria Kovacs, PhD
Department of Psychiatry
University of Pittsburgh
Pittsburgh, PA

Patrick McGorry, MD
Orygen Youth Health Research Centre
Centre for Excellence in Youth Mental Health
Department of Psychiatry
University of Melbourne
Melbourne, Australia

Kathleen Ries Merikangas, PhD
Genetic Epidemiology Branch
Intramural Research Program
National Institute of Mental Health
Bethesda, MD

Alexander J. Millner, AM
Department of Psychology
Harvard University
Cambridge, MA

Ramin Mojtabai, MD, PhD, MPH
Department of Mental Health
Bloomberg School of Public Health
Department of Psychiatry
Johns Hopkins University
Baltimore, MD

Rudolf Moos, PhD
Department of Veterans Affairs Health Care System
Stanford University
Palo Alto, CA

Yuval Neria, PhD
Department of Psychiatry
Columbia University
New York, NY

Matthew Nock, PhD
Department of Psychology
Harvard University
Cambridge, MA

Carlos N. Pato, MD
Department of Psychiatry
Keck School of Medicine
University of Southern California
Los Angeles, CA

Michele T Pato, MD
Department of Psychiatry
Keck School of Medicine
University of Southern California
Los Angeles, CA

Santiago Papini, MA
New York State Psychiatric Institute
Columbia University
New York, NY

Katharine Reiner van der Hoorn, BA
New York State Psychiatric Institute
Teachers College, Columbia University
New York, NY

Michal Rosenberg, BA
The Bob Shapell School of Social Work
Tel Aviv University
Tel Aviv, Israel

Edye Schwartz, DSW, LCSW-R
New York Association of Psychiatric Rehabilitation Services, Inc.
Albany, New York

Erel Shvil, PhD
Department of Psychiatry
Columbia University
New York State Psychiatric Institute
New York, NY

Avigal Snir, PhD
The Bob Shapell School of Social Work
Tel Aviv University
Tel Aviv, Israel

Janet L. Sobell, PhD
Department of Psychiatry
Keck School of Medicine
University of Southern California
Los Angeles, CA

Zahava Solomon, PhD
The Bob Shapell School of Social Work
Tel Aviv University
Tel Aviv, Israel

Gregory M. Sullivan, MD
Department of Psychiatry
Columbia University
New York State Psychiatric Institute
New York, NY

Peter Szatmari, MD, MSc
Child, Youth and Family Program
Centre for Addiction and Mental Health
University of Toronto
Toronto, ON

Christine Timko, PhD
Department of Veterans Affairs Health Care System
Menlo Park, CA

Mauricio Tohen, MD, DrPH, MBA
Department of Psychaitry
University of New Mexico
Albuquerque, NM

Robert B. Zipursky, MD
Department of Psychiatry & Behavioural Neurosciences
McMaster University
Hamilton, Ontario