Immunopsychiatry

A Clinician's Introduction to the Immune Basis of Mental Disorders

Edited by Antonio L. Teixeira and Moises E. Bauer

Presents an accessible introduction to the field of Immunopsychiatry
Summarizes available data on immune/inflammatory dysfunction in psychiatric disorders
Reviews potential of immune mechanisms as biomarkers and therapeutic targets
Explores challenges of incorporating immunopsychiatry into clinical practice

Immunopsychiatry

A Clinician's Introduction to the Immune Basis of Mental Disorders

Edited by Antonio L. Teixeira and Moises E. Bauer

Description

In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area.

This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology.

Immunopsychiatry

A Clinician's Introduction to the Immune Basis of Mental Disorders

Edited by Antonio L. Teixeira and Moises E. Bauer

Chapter 1: Overview of the immune system
Chapter 2: Immune-neuropharmacology
Chapter 3: Immune mechanisms affecting CNS functioning
Chapter 4: Immune mechanisms and CNS development
Chapter 5: The immune system as a sensor capable to affect other homeostatic systems
Chapter 6: Microbiota-Gut-Brain Axis and Neuropsychiatric Disorders
Chapter 7: Investigating immune changes in the psychiatric patient
Chapter 8: Immune dysfunction: a common feature of major psychiatric disorders?
Chapter 9: Immunology of substance use disorder
Chapter 10: Immune system dysregulation and schizophrenia
Chapter 11: Depression as a neuroinflammatory condition
Chapter 12: Immunology of bipolar disorder
Chapter 13: immunology of post-traumatic stress disorder (PTSD)
Chapter 14: Immunology of eating disorders
Chapter 15: Immunology of late-life psychiatric disorders and dementias
Chapter 16: Immune-based biomarkers and therapies in psychiatry: future prospects

Immunopsychiatry

A Clinician's Introduction to the Immune Basis of Mental Disorders

Edited by Antonio L. Teixeira and Moises E. Bauer

Author Information

Edited by Antonio L. Teixeira, Professor of Psychiatry, University of Texas Health Sciences Center at Houston, and Edited by Moises E. Bauer, Professor of Immunology, Pontifical Catholic University

Antonio L. Teixeira, MD is Professor of Psychiatry at the University of Texas Health Sciences Center in Houston, Texas. Moises E. Bauer, PhD, senior researcher in Neuroimmunology, Head of the Laboratory of Stress Immunology (School of Sciences, PUCRS, Brazil). Professor of Immunology at the Pontifical Catholic University in Porto Alegre, Brazil.

Contributors:

Samantha Alvarez-Herrera
Department of Psychoimmunology
National Institute of Psychiatry
Mexico City, Mexico

Izabela G. Barbosa, MD
Department of Neurology
University Hospital
Belo Horizonte, Brazil

Consuelo Walss Bass, PhD
Associate Professor
Department of Psychiatry and Behavioral Sciences
and
Director, Psychiatric Genetics Program
University of Texas Health Science Center at Houston
Houston, TX
USA

Moisés E. Bauer, PhD
Associate Professor of Immunology
Department of Immunology
Pontificia Universidade Católica do Rio Grande do Sul
Porto Alegre, Brazil

Bernhard Baune, MD
Head of Psychiatry
Department of Psychiatry
University of Adelaide
Adelaide, South Australia

Hugo Besedovsky, MD
Professor
Philipps University of Marburg
Marburg, Germany

Alessandra Borsini, PhD
Postdoctoral Research Associate
Department of Psychological Medicine
King's College London
London, UK

Eduardo Candelario-Jalil, PhD
Assistant Professor
Department of Neuroscience
University of Florida
Gainesville, FL
USA

Karine Clément, MD, PhD
Professor
Department of Cardiometabolism
Pitié-Salpêtrière hospital
Paris, France

John Cryan, PhD
Professor & Chair
Department of Anatomy & Neuroscience
University College Cork
County Cork, Ireland

Timothy G. Dinan, MD
Professor
Department of Psychiatry
and
Principal Investigator
APC Microbiome Institute
University College Cork
County Cork, Ireland

Breno Satler Diniz, MD, PhD
Assistant Professor
Department of Psychiatry and Behavioral Sciences
University of Texas Health Science Center at Houston
Houston, TX
ISA

Adaliene Versiani Matos Ferreira, PhD
Associate Professor
Department of Nutrition
Federal University of Minas Gerais
Belo Horizonte, Brazil

Gilliard Lach, PhD
Senior Postdoctoral Fellow
APC Microbiome Institute
University College Cork
County Cork, Ireland

Marion Leboyer, MD, PhD
Professor of Psychiatry
Department of Psychiatry
University of Paris Est
Paris, France

Geneviève Marcelin, PharmD, PhD
Professor
Department of Medicine
Pierre et Marie Curie University
and
Clinical Virologist
Pitié Salpêtrière Hospital
Paris, France

Laís Bhering Martins, PhD
Professor
Department of Nutrition
Federal University of Minas Gerais
Belo Horizonte, Brazil

Nayara Mussi Monteze, PhD
Adjunct Professor, Postgraduate Coordinator
Department of Nutrition
Federal University of Minas Gerais
Belo Horizonte, Brazil

José Oliveira, PhD
Associate Professor
Center of Investigation in Physical Activity
University of Porto
Porto, Portugal

Carmine Pariante
Professor of Biological Psychiatry and Head of section
Department of Psychological Medicine <https://kclpure.kcl.ac.uk/portal/en/organisations/psychological-medicine(e774a2e2-f915-4fdb-871a-afa1a3766a7c).html>
King's College London
London, UK

Lenin Pavón, PhD
Chief
Department of Psychoimmunology
National Institute of Psychiatry
Mexico City, Mexico

Antonio Carlos Pinheiro de Oliveira, PhD
Assistant Professor
Department of Pharmacology
Federal University of Minas Gerais
Belo Horizonte, Brazil

Adriana Del Rey, MD
Institute for Normal and Pathological Physiology & Immunology
University of Marburg
Marburg, Germany

Natalia Pessoa Rocha, PharmD, PhD
Clinical Researcher
Department of Psychiatry and Behavioral Sciences
University of Texas Health Science Center at Houston
Houston, TX
USA

Wilson Savino, PhD
Vice President
Department of Neurology
Oswaldo Cruz Institute
Rio de Janeiro, Brazil

Vivian Thaise da Silveira
Graduate Student
Department of Neuroscience
Federal University of Minas Gerais
Belo Horizonte, Brazil

Ana Cristina Simoes-e-Silva, MD, PhD
Faculty of Medicine
Department of Pediatrics
Federal University of Minas Gerais
Belo Horizonte, Brazil

Gaurav Singhal, MD, PhD
Department of Psychiatry
Royal Adelaide Hospital
Adelaide, South Australia

Jair C. Soares, MD, PhD
Professor & Chairman
Department of Psychiatry and Behavioral Sciences
University of Texas Health Science Center at Houston
Houston, TX
USA

Laura Stertz, PhD
Postdoctoral Research Fellow
Department of Psychiatry and Behavioral Sciences
University of Texas Health Science Center at Houston
Houston, TX
USA

Laure Tabouy, PhD
Postdoctoral Researcher in Neurosciences, Genetics, and Microbiome
Department of NeuroPSI and Brain Development
Université Paris-Saclay
Paris, France

Erica Leandro Vieira, PhD
Postdoctoral Investigator
Department of Biochemistry and Immunology
Federal University of Minas Gerais
Belo Horizonte, Brazil

Andrea Wieck, PhD
Visiting Researcher
Department of Microbiology and Immunology
Dartmouth College
Hanover, NH
USA

Patricia Zunszain, PhD
Department of Psychological Medicine
King's College London
London, UK