Immune and Inflammatory Responses in the Nervous System

Second Edition

Nancy Rothwell and Sarah Loddick

Molecular and Cellular Neurobiology Series

This new edition covers recent advances in understanding immunological and inflammatory responses in the nervous system. This research is driven ...

Immune and Inflammatory Responses in the Nervous System

Second Edition

Nancy Rothwell and Sarah Loddick

Molecular and Cellular Neurobiology Series

Description

This new edition covers recent advances in understanding immunological and inflammatory responses in the nervous system, research driven by the potential to use knowledge of the molecules and mechanisms involved to intervene in, and arrest, neurodegenerative disease processes.

Immune and Inflammatory Responses in the Nervous System covers developmental aspects of immune/inflammatory responses in the CNS, basic aspects of glial function, as well as inflammatory mediators, their mechanisms of action, clinical importance and sites of infection. There is also coverage of the major diseases of the CNS, including stroke, brain injury, multiple sclerosis and Alzheimer's disease. Throughout, the focus is on the underlying basic neuroscience, clinical relevance and the potential for therapeutic interventions.

This will be an invaluable aid to understanding and improving the diagnosis of neuroimmune diseases and determining therapeutic measures.

The contributors are all leading experts in the field and the content will be of interest to neuroscientists, neurologists, neuropathologists, neurosurgeons and immunologists.

Immune and Inflammatory Responses in the Nervous System

Second Edition

Nancy Rothwell and Sarah Loddick

Molecular and Cellular Neurobiology Series

1:Developmental influences on inflammation in the brain, Anthony & Campbell
2:Imaging inflammation in the brain, Banati
3:Astrocytic networks and brain injury, Verkhratsky & Jones
4:Blood-brain barrier and perivascular cells, Johansson
5:CNS responses to peripheral insults, Luheshi & Konsman
6:Inflammatory events in focal cerebral ischaemia, del Zoppo & Hallenbeck
7:Cytokines and neurodegeneration, Rothwell & Loddick
8:Inflammatory responses to traumatic brain injury: an overview for the millennium, Morganti-Kossman et al
9:Inflammatory demyelination and axonopathy in the CNS, Cuzner & Woodroofe
10:CNS immune reactions in Alzheimer's disease, Rogers et al
11:Transplantation of neuronal and non-neuronal cells into the brain, Widner

Immune and Inflammatory Responses in the Nervous System

Second Edition

Nancy Rothwell and Sarah Loddick

Molecular and Cellular Neurobiology Series

Author Information

Nancy Rothwell, School of Biological Sciences, University of Manchester, UK, and Sarah Loddick, School of Biological Sciences, University of Manchester UK

Contributors:

Dr Daniel Anthony, School of Biological Sciences, University of Southampton, UK
Dr Richard Banati, MRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith, London, UK
Dr Sandra Campbell, School of Biological Sciences, University of Southampton, UK
Prof Louise Cuzner, Department of Neuroinflammation, Institute of Neurology, London, UK
Dr Gregory del Zoppo, Dept of Molecular & Experimental Medicine, Scripps Research Insitute, La Jolla CA, USA
Dr J Hallenbeck, National Institutes of Neurological Disorders & Stroke, NIH, Bethesda MD, USA
Prof Barbro Johansson, Wallenberg Neuroscience Center, Lund, Sweden
Dr O Jones, School of Biological Sciences, University of Manchester, UK
Dr J-P Konsman, Laboratory of Integrative Neurobiology, INRA-INSERM U394, Bordeaux, France
Dr Thomas Kossman, The Alfred Hospital, Monash University, Melbourne, Vic, Australia
Dr Carl Kovelowski, Sun Health Research Institute, Sun City AZ, USA
Dr Sarah Loddick, School of Biological Sciences, University of Manchester, UK
Dr Giamal Luheshi, The Douglas Hospital Research Centre, McGill University, Verdun, Quebec, Canada
Dr Cristina Morganti-Kossman, The Alfred Hospital, Monash University, Melbourne, Vic, Australia
Dr Mario Rancan, Department of Surgery, University Hospital, Zurich, Switzerland
Dr Joseph Rogers, Sun Health Research Institute, Sun City AZ, USA
Prof Nancy Rothwell, School of Biological Sciences, University of Manchester, UK
Dr Philip Stahel, Dept of Trauma & Reconstructive Surgery, University Hospital Benjamin Franklin, Free University of Berlin, Germany
Dr Ron Strohmeyer, Sun Health Research Institute, Sun City AZ, USA
Dr Alex Verkhratsky, School of Biological Sciences, University of Manchester, UK
Dr Hakan Widner, Department of Neurology, Lund University Hospital, Lund, Sweden
Dr Nicola Woodroofe, Biomedical Research Centre, Sheffield Hallam University, Sheffield, UK

Immune and Inflammatory Responses in the Nervous System

Second Edition

Nancy Rothwell and Sarah Loddick

Molecular and Cellular Neurobiology Series

Reviews and Awards

"This well-structured and balanced account of our current knowledge of immune and inflammatory aspects of CNS disorders will appeal to researchers and clinicians alike." - Journal of Neurology

". . . provides a clear, concise, informative, and most importantly, readable, collection of up-to-date essays on various aspects of inflammation in the CNS. Because of the diversity of the contributor's view points, I think that it would provide a good introduction for those unfamiliar with inflammation or for those unfamiliar with the special problems relating to the nervous system." - Brain