Discovery and Synthesis of Crop Protection Products

Edited by Peter Maienfisch and Thomas M. Stevenson

ACS Symposium Series

Synthesizes the most recent research and new directions in the chemistry of agrochemicals, as well as new research approaches, tools and directions in the crop protection field including nematicides, biologicals and natural products
Demonstrates the exciting, new innovations in chemical crop protection research that have been made in recent years and the new advantages that continue to be discovered and introduced.

Discovery and Synthesis of Crop Protection Products

Edited by Peter Maienfisch and Thomas M. Stevenson

Description

Modern agribusiness is one of the main generators of employment and income worldwide and plays a vital role in improving the production, quality, and quantity of food, feed, fiber, and fuel ensuring our world has the safest and most nutritious, abundant, and sustainable food supply possible. The global agribusiness industry with its offerings such as insecticides, herbicides, and fungicides as well as biotechnology products contributes to growing public expectations for food security and agricultural sustainability while addressing the industry's global challenges, such as population growth and rising caloric consumption, increasing environmental stresses across the globe, a changing regulatory landscape, development of resistance to existing active ingredients and traits by investing in effective R&D programs and inventing new solutions.

The book provides an update on state of the art crop protection research and highlights the pivotal role of novel chemistries for modern crop protection. Recent research and new directions in the synthesis and chemistry of agrochemicals, as well as new research approaches, tools and directions in the crop protection field including nematicides, biologicals and natural products are described and details on the design, synthesis, biology and/or structure-activity relationships of a series of new chemical entities targeting fungicides, insecticides, herbicides and nematicides provided. Furthermore future directions for advancing research and regulation of agricultural chemistry and pest management science, promoting public health, and preserving environmental quality are covered as well.

Discovery and Synthesis of Crop Protection Products

Edited by Peter Maienfisch and Thomas M. Stevenson

ACS Symposium Series

1. Modern Agribusiness - Markets, Companies, Benefits and Challenges
2. Building a Successful Crop Protection Pipeline: Molecular Starting Points for Discovery
3. New Paradigms in Crop Protection Research: Registrability and Cost of Goods
4. Pesticide Invention Model in a Japanese Company
5. Natural Products for Crop Protection: Evolution or Intelligent Design
6. Leveraging Mammalian Therapeutic Research To Identify Novel Lead Chemistries for Crop Protection
7. Discovery of New Herbicide Modes of Action with Natural Phytotoxins
8. What Makes a Good Compound against Sucking Pests?
9. Plant- or Fungal-Produced Conophthorin as an Important Component of Host Plant Volatile-Based Attractants for Agricultural Lepidopteran Insect Pests
10. Tioxazafen: A New Broad-Spectrum Seed Treatment Nematicide
11. The Discovery of Oxathiapiprolin: A New, Highly-Active Oomycete Fungicide with a Novel Site of Action
12. Novel Substituted Anilinopyrimidine Compounds: Design, Synthesis, and Fungicidal Activity
13. Succinate Dehydrogenase: An Ideal Target for Fungicide Discovery
14. Mollisin: A Promising Antifungal Natural Product
15. Combinatorial Approach To Lead Generation and the Discovery of a Potent Septoria tritici Fungicide
16. HPPD Herbicide-Safener Combinations as Resistance Breaking Solutions for 21st Century Agriculture
17. Indaziflam: An Innovative Broad Spectrum Herbicide
18. Discovery and SAR of Halauxifen Methyl: A Novel Auxin Herbicide
19. 3-Sulfonylisoxazoline Derivatives as Novel Herbicides
20. Broad-Spectrum PPO-Inhibiting N-Phenoxyphenyluracil Acetal Ester Herbicides
21. New Approaches to the Design and Synthesis of Inhibitors of Acetyl-CoA Carboxylase
22. 4-Azolyl-5-Hydroxy Pyridazinones: Potent Grass Herbicides
23. Chemical Control of Root Parasitic Weeds
24. Sivanto® - A Novel Insecticide with a Sustainable Profile
25. Pharmacophore Based Design and Synthesis of Novel Neonicotinic Insecticides
26. Triflumezopyrim: Discovery and Optimization of a Mesoionic Insecticide for Rice
27. Synthesis and Biological Activity of a Novel Acaricide, Pyflubumide
28. Synthesis and Insecticidal Activity of New 2-Aryl-3,5-dihydro-2H-1,4- Benzoxazepine Derivatives
29. Synthesis and Insecticidal Activity of New Benzyl- and Indanyl-Oxazolines, Thiazolines and Alkoxy-Alkyl-Imidazolines
30. Multiple Sites of Insecticidal Action in Ionotropic GABA Receptors
31. Insect Voltage-Gated Chloride Channels as a Possible Insecticide Target Site

Discovery and Synthesis of Crop Protection Products

Edited by Peter Maienfisch and Thomas M. Stevenson

ACS Symposium Series

Author Information

Edited by Peter Maienfisch, Research Portfolio Manager, Insectisides and Seed Care, Syngenta Crop Protection AG, and Edited by Thomas M. Stevenson, Research Chemist, DuPont Crop Protection

Dr. Peter Maienfisch, Research Portfolio Manager Insecticides & Seedcare, studied chemistry at the ETH in Zürich, Switzerland, where he received his PhD in 1983. After a post-doctoral stay at Caltech (Pasadena, CA, USA) Peter joined Ciba-Geigy in Basel in 1984. In 2015, he became Honorary Professor of the East China University of Science and Technology (ECUST), Shanghai, China. Furthermore he is the inventor of thiamethoxam (Actara®, Cruiser®, one of the leading insecticides world-wide) and is a member of the Swiss & American Chemical Societies and the CHIMIA Editorial Board.

Dr. Thomas M. Stevenson graduated with a B.S. in chemistry from Saint Louis University in 1979 where he carried out undergraduate research with Harold A. Dieck funded by a Monsanto Summer Fellowship. He received a Ph.D. in organic chemistry from the University of Illinois in 1983, under the supervision of Nelson J. Leonard. After postdoctoral research at the University of Geneva from 1983 to 1985 with Wolfgang Oppolzer, Stevenson joined DuPont Crop Protection as a research chemist, rising in ranks to his current position as senior research fellow