Depression as a Systemic Illness

Edited by James J. Strain and Michael Blumenfield

Demonstrates a conceptual framework for understanding the physiology of depression
Highlights the stress of depression on various medical disorders
Illustrates the importance of recognizing depression as a systemic disease and an essential area of inquiry in diagnostic and treatment settings

Depression as a Systemic Illness

Edited by James J. Strain and Michael Blumenfield

Description

Although depression has been long considered an exclusively mental disorder, this book highlights the importance of recognizing it as a systemic—physical—illness. The chapters herein present key findings from research on animal models before proceding on to examine the "allostatic" load that depression bears on the body, commonly observed patterns of depression, and illnesses that it is likely to adversely effect—through mechanisms other than that of non-compliance with treatment. The authors also explore various diagnostic dilemmas including symptom-driven, phenomenologic approaches, and discuss drug-drug interactions and the use of unique electronic health records as collaborating agents to the physician.

Depression as a Systemic Illness emphasizes the need for the primary care physician to be the first agent to care for "garden variety" depressive disorders and the need to alter medical school and residency training to accommodate the development of the necessary skills, knowledge and attitudes to fulfill this goal. Its unique approach and presentation of depression makes it a key resource for clinicians within the fields of both psychiatry and primary care medicine.

Depression as a Systemic Illness

Edited by James J. Strain and Michael Blumenfield

1. The Biological Basis of Depression: Insights from Animal Models
Eric J. Nestler
2. The Brain and Body on Stress: Allostatic Load and Mechanisms for Depression and Dementia
Bruce S. McEwen and Natalie L.Rasgon
3. Depression as a recurrent, progressive illness: Need for long-term prevention
Robert M. Post
4. Biological effects of Depression in Cardiac Illness
Nicole Mavrides and Charles Nemeroff
5. Biological effects of depression: risk for and occurrence of stroke
Bradleigh Hayhow and Sergio Starkstein
6. Depression and Cancer
Daniel C McFarland and Jimmie Holland
7. Depression in Neurologic Disorders: Comorbidity or another clinical manifestation?
Andres M. Kanner
8. Depression and Diabetes and Endocrine Disorders
Eduardo A. Colón
9. Wound Healing and Depression
Frederick J Stoddard Jr and Robert L. Sheridan
10. Psychopharmacological Issues in the Treatment of Depression as a Systemic Illness: Focus on Adverse Drug Reactions and Drug-Drug Interactions
Kelly L. Cozza, Rita Rein, Gary H. Wynn, and Eric G. Meyer
11. Diagnostic Dilemmas
James J. Strain, Patricia Casey, and Peter Tyrer
12. Models of Mental Health Training for Non-Psychiatric Physicians: Beyond Collaborative Care
James J. Strain
13. An Updated Electronic Health Record (EHR) for Depression Management
Jay J. Strain, Akhil Shenoy, and James J. Strain
Epilogue
James J. Strain and Michael Blumenfield

Depression as a Systemic Illness

Edited by James J. Strain and Michael Blumenfield

Author Information

Edited by James J. Strain, Professor of Psychiatry, Professor of Medical Education, Master Teacher, Icahn School of Medicine at Mount Sinai, and Edited by Michael Blumenfield, Sidney E. Frank Distinguished Professor Emeritus of Psychiatry and Behavioral Sciences, New York Medical College

James J. Strain, MD Professor of Psychiatry Professor of Medical Education Master Teacher Icahn School of Medicine at Mount Sinai New York, New York

Michael Blumenfield, MD Sidney E. Frank Distinguished Professor Emeritus of Psychiatry and Behavioral Sciences New York Medical College Valhalla, New York

Contributors:

Michael Blumenfield, MD
Sidney E. Frank Distinguished Professor Emeritus of
Psychiatry and Behavioral Sciences
New York Medical College
Valhalla, New York

Patricia Casey, MD
Professor of Psychiatry
University of Dublin
Dublin, Ireland

Eduardo A. Colón Navarro, MD
Chief of Psychiatry
Hennepin County Medical Center
Rochester, MN
Professor of Psychiatry, University of Minnesota
Chairman Department of Psychiatry
Hennepin County Medical Center
Minneapolis, MN

Kelly L. Cozza, MD, DFAPA, FAPM
Associate Professor, Psychiatry Clinical Clerkship Coordinator
Department of Psychiatry
Scientist, Center for the Study of Traumatic Stress
Uniformed Services University of the Health Sciences
Bethesda, MD

Bradleigh Hayhow, MD. FRANZCP
Hon. Academic Fellow Melbourne Neuropsychiatry Centre
The University of Melbourne Clinical Senior Lecturer
Department of Psychiatry
The University of Western Australia
Perth, WA, Australia

Jimmie Holland, MD
Department of Psychiatry and Behavioral Sciences
Memorial Sloan Kettering Cancer Center
New York, NY

Andres M. Kanner, M.D., F.A.N.A,
Professor of Clinical Neurology
Director, Comprehensive Epilepsy Center
Head, Epilepsy Division
Department of Neurology
University of Miami
Miller School of Medicine
Miami, FL

Bruce S. McEwen, PhD
Laboratory of Neuroendocrinology
The Rockefeller University,
New York, NY

Daniel C McFarland D.O.,
Division of Network Medicine Services,
Department of Medicine,
Memorial Sloan Kettering Cancer Center,
West Harrison, NY

Eric G. Meyer, MD
Major, Medical Corps, US Air Force
Assistant Professor
Department of Psychiatry
Scientist, Center for the Study of Traumatic Stress
Uniformed Services University
Bethesda, MD

Charles Nemeroff, MD
Department of Psychiatry and Behavioral Sciences
Center on Aging
University of Miami Miller School of Medicine
Miami, FL

Eric J. Nestler, PhD, MD
Head of Brain Institute
Icahn School of Medicine at Mount Sinai
Fishberg Department of Neuroscience and Friedman Brain Institute
New York, NY

Robert M. Post, MD
Bipolar Collaborative Network
Bethesda, MD

Natalie L.Rasgon, MD
Department of Psychiatry and Behavioral Sciences
Stanford University School of Medicine
Palo Alto, CA

Rita Rein, MD
Captain, Medical Corps, US Army
Psychiatry Resident
Walter Reed and Uniformed Services University National
Capital Consortium
Psychiatry Residency Program
Bethesda, MD

Akhil Shenoy, MD
Assistant Professor of Psychiatry
Icahn School of Medicine at Mount Sinai
New York, NY

Robert L. Sheridan MD
Harvard Medical School
Boston, MA

Sergio Starkstein, MD, PhD, FRANZCP
Professor of Psychiatry
Department of Psychiatry,
The University of Western Australia

Frederick J Stoddard Jr, MD
Harvard Medical School
Boston, MA

James J. Strain, MD
Professor of Psychiatry
Professor of Medical Education
Master Teacher
Icahn School of Medicine at Mount Sinai
New York, New York

Jay J. Strain, MD
Assistant Professor of Surgery
Thomas Jefferson School of Medicine
Einstein Healthcare Network,
Philadelphia, PA

Peter Tyrer, MD,
Professor of Psychiatry
Imperial College, London, England

Gary H. Wynn, MD
Lieutenant Colonel, Medical Corps, US Army
Associate Professor, Assistant Chair
Department of Psychiatry
Scientist, Center for the Study of Traumatic Stress
Uniformed Services University
Bethesda, MD

Depression as a Systemic Illness

Edited by James J. Strain and Michael Blumenfield

Reviews and Awards

"Researchers focusing on mood disorders and collaborative care models would find this to be a useful resource...The book is an especially useful resource for clinicians and researchers in consult-liaison psychiatry and other collaborative specialties." - Doody's