Cancer Epidemiology

Low- and Middle-Income Countries and Special Populations

Edited by Amr Soliman, David Schottenfeld, and Paolo Boffetta

In addition to LMICs, addresses reports on specific studies conducted in Africa, Asia, Central and South America, and the Middle East, as well as studies in Australia, Europe, North America and in populations that migrate from LMICs to developed countries
Includes detailed training requirements and examples of curricula that will enable graduate and post-graduate students to pursue careers in international cancer epidemiologic research
Summarizes and reviews research studies that are in progress concerning major prevalent cancers of the breast, uterine cervix, lung and bronchus, upper aerodigestive tract, stomach, liver, colon, and HIV-associated cancers

Cancer Epidemiology

Low- and Middle-Income Countries and Special Populations

Edited by Amr Soliman, David Schottenfeld, and Paolo Boffetta

Description

According to the World Health Organization's 2008 GLOBOCAN report, 64% of global cancer deaths — and 56% of cancer cases — were registered in countries in Africa, Asia, or Latin America. So while cancer is unquestionably a global burden, its reach in the developing world points to the need for specialized study on cancer in these countries.

Cancer Epidemiology: Low- and Middle-Income Countries and Special Populations reviews the current status of cancer epidemiologic research and training — rationale, requisite infrastructure, methodologic principles, and illustrative examples in low- and middle-income countries — in order to facilitate future advances by trained health professionals. The result is a valuable resource for both program leaders and graduate and post-graduate students pursuing careers in international cancer epidemiologic research.

Cancer Epidemiology

Low- and Middle-Income Countries and Special Populations

Edited by Amr Soliman, David Schottenfeld, and Paolo Boffetta

Section 1: Multidisciplinary Perspectives
1. Burden of Cancer in Low- and Middle-Income Countries
Maria Paula Curado, Paolo Boffetta, David Schottenfeld, Jean-Marie Dangou, Karina Braga Ribeiro
2. Migrant Studies
Song-Yi Park and Laurence N. Kolonel
3. Molecular Epidemiology Studies in Cancer
Kelly Hirko, Maria Iniesta Donate, Sofia Merajver
4. Opportunities for Cancer Genetic Research
Oluwafemi Oluwole, Yonglan Zheng, Olufunmilayo Olopade
5. Cancer Screening in Low- and Middle-Income Countries
R. Sankaranarayanan, Somanathan Thara, Youlin Qiao, Twalib Ngoma, Raul Murillo
6. Behavioral, Social, and Cultural Aspects of Epidemiologic Studies in Low- and Middle-Income Countries and in Special Populations
Robert Chamberlain
7. Ethical Issues in Cancer Epidemiologic Studies
Steven S. Coughlin
Section 2: Methodological Principles in Conducting International Studies
8. Case-control Studies in Low- and Middle-Income Countries
Farin Kamangar, Kyle Esdaille, Farhad Islami
9. Cohort Studies in Low- and Middle-Income Countries
Stephanie Melkonian, Yu Chen, Habibul Ahsan
10. Molecular Epidemiology in LMIC
Hongbing Shen and Hongxia Ma
11. Methodological Issues in International Multicentric Studies, Including the Role of Consortia in International Cancer Epidemiology
Farhad Islami and Paolo Boffetta
Section 3: Cancer Epidemiology Research Training in LMI Countries and Special Populations: Needs and Opportunities
12. Cancer Epidemiology Research Training in LMI Countries and Special Populations: Needs and Opportunities
Amr Soliman
13. Cancer Epidemiology in Schools of Public Health and Medical Schools: Culture, Infrastructure, and Curricula
Amr Soliman
14. University Resources for Academic and Field Research Training in Cancer Epidemiology
Amr Soliman and Robert Chamberlain
15. Non-University Training Programs in Cancer Epidemiology, Emphasizing Participation from LMI Countries
Jessica Fapeol-Badger
16. Needs and Opportunities for Epidemiologic Training of Early-career Clinicians and Scientists Seeking to Conduct Cancer Research in LMI Countries
Amr Soliman and Robert Chamberlain
Section 4: Illustrative Examples of Collaborative Field Studies
17. Hepatitis B Virus, Aflatoxin and Primary Liver Cancer
W. Thomas London, Timothy M. Block, Katherine A. McGlynn
18. HPV and Cervical Cancer
Rolando Herrero
19. Studies of Tobacco Smoking and Control
Priscilla S. Reddy, Shamagonam James, Nasheen Naidoo, Ronel Sewpaul, Ken Resnicow, and Anthony Mbewu
20. Cancer and HIV in Less Developed Countries
Sam M. Mbulaiteye
21. Breast Cancer Early Detection and Clinical Guidelines
David B. Thomas, Raul H. Murillo, Kardinah, and Benjamin O. Anderson
Section 5: Future Directions: Emerging Opportunities and Challenges
22. Future Directions: Emerging Opportunities and Challenges
Amr S. Soliman, David Schottenfeld, and Paulo Boffetta

Cancer Epidemiology

Low- and Middle-Income Countries and Special Populations

Edited by Amr Soliman, David Schottenfeld, and Paolo Boffetta

Author Information

Edited by Amr Soliman, Professor and Chair of Epidemiology, University of Nebraska Medical Center, Collage of Public Health, Omaha, USA, David Schottenfeld, Searle Professor Emeritus and former Chair of the Department of Epidemiology, University of Michigan, Ann Arbor, USA, and Paolo Boffetta, Director of the Institute for Translational Epidemiology and Associate Director of Population Sciences, Tisch Cancer Institute at Mount Sinai Hospital, New York, USA

Amr Soliman, MD, PhD, is Professor and Chair of Epidemiology, University of Nebraska Medical Center. David Schottenfeld, MD, MSc, is the Searle Professor Emeritus and former Chair of the Department of Epidemiology, University of Michigan. Paolo Boffetta, MD, MPH, is Director of the Institute for Translational Epidemiology and Associate Director of Population Sciences, Tisch Cancer Institute at Mount Sinai Hospital.

Contributors:

Habibul Ahsan, M.D., M.Med.Sc.
Center for cancer Epidemiology and Prevention
Department of Health Studies
The University of Chicago
Chicago, Illinois USA

Benjamin O. Anderson, MD
Chair and Director, Breast Health Global Initiative
Joint Member, Fred Hutchinson Cancer Research Center
Professor of Surgery and Global Health-Medicine
University of Washington
Seattle, Washington USA

Timothy M. Block, Ph.D.
President and Director, Institute for Hepatitis and Virus Research
President and Director, Hepatitis B Foundation
Director, Drexel Institute for Biotechnology and Virology Research
Professor, Microbiology and Immunology
Drexel University College of Medicine
Doylestown, Pennsylvania USA

Paolo Boffetta, M.D.
Director, Institute for Translational Epidemiology
Associate Director, Tisch Cancer Insititute
Mount Sinai School of Medicine
New York, New York USA
Vice-President, Research
International Prevention Research Institute
Lyon, France

Robert Chamberlain, Ph.D.
Professor of Epidemiology
University of Texas
M.D. Anderson Cancer Center
Austin, Texas USA
University of Nebraska Medical Center
College of Public Health
Omaha, Nebraska USA

Yu Chen, Ph.D., M.D.
Professor, Department of Environmental Medicine
New York University
Medical Center
New York, New York USA

Steven S. Coughlin, Ph.D.
Professor, Department of Epidemiology
Rollins School of Public Health
Emory University
Atlanta, Georgia USA
Epidemiology Program
Post-Deployment Health
Office of Public Health
Department of Veterans Affairs
Washington, D.C. USA

Maria Paula Curado, M.D., Ph.D.
Senior Researcher
International Prevention Research Institute
Lyon, France

Jean-Marie Dangou, Ph.D.
Regional Adviser for Cancer Control
Disease Prevention & Control Cluster (DPC)
WHO Regional Office for Africa
Cité Djoué, Brazzaville, Congo Republic

Maria Iniesta DoÑate
Research Fellow
University of Michigan School of Medicine
Internal Medicine
Ann Arbor, Michigan USA

Kyle Esdaille, Dr.P.H., M.P.H., C.P.H.
School of Community Health and Policy
Morgan State University
Baltimore, Maryland USA

Jessica M. Faupel-Badger,Ph.D., M.P.H
Deputy Director
Cancer Prevention Fellowship Program
Division of Cancer Prevention
National Cancer Institute
Bethesda, Maryland USA

Rolando Herrero, M.D., Ph.D.
Head of Prevention and Implementation Group
International Agency for Research on Cancer
Lyon, France

Kelly Hirko, MPH
Ph.D. Candidate
University of Michigan School of Public Health
Department of Epidemiology
Ann Arbor, Michigan USA

Farhad Islami, M.D., Ph.D.
Instructor
Digestive Disease Research Center
Tehran University of Medical Sciences
Tehran, Iran
Tisch Cancer Institute and Insitute of Transitional Epidemiology
Mount Sinai School of Medicine
New York, New York USA

Shegs James, Ph.D.
Specialist Scientist
Health Promotion Research and Development Unit
Medical Research Council
Pietermaritzburg, South Africa

Farin Kamangar
Professor and Chairman
Department of Public Health Analysis
School of Community Health and Policy
Morgan State University
Baltimore, Maryland USA

Kardinah, M.D.
National Cancer Center
Dharmais Hospital
Jakarta, Indonesia

Laurence N. Kolonel, M.D., Ph.D.
Professor
Cancer Epidemiology Program
University Hawaii Cancer Center
Honolulu, Hawaii USA

W. Thomas London, M.D.
Chairman
Fox Chase Cancer Center
Institutional Review Board
Philadelphia, Pennsylvania USA

Hongxia Ma, M.D., Ph.D.
Instructor
Department of Epidemiology & Biostatistics
School of Public Health
Nanjing Medical University
Nanjing, Jiangsu Province
China

Anthony Mbewu, M.B.B.S., M.D., F.R.C.P
Honorary Professor of Medicine and Cardiology
Department of Medicine
Faculty of Health Sciences
University of Cape Town
Cape Town, South Africa

Sam M. Mbulaiteye, M.D.
Investigator
Infections and Immunoepidemiology Branch
Division of Cancer Epidemiology and Genetics
National Cancer Institute
National Institutes of Health
Department of Health and Human Services
Rockville, Maryland USA

Katherine A. McGlynn, Ph.D., M.P.H.
Deputy Chief
Hormonal and Reproductive Epidemiology Branch
Division of Cancer Epidemiology and Genetics
National Cancer Institute
National Institutes of Health
Department of Health and Human Services
Rockville, Maryland USA

Stephanie Melkonian,
Graduate Research Assistant
Center for Cancer Epidemiology and Prevention
Department of Health Studies
The University of Chicago
Chicago, Illinois USA

Sofia D. Merajver, M.D., Ph.D.
Professor of Internal Medicine and Epidemiology
University of Michigan
School of Medicine
School of Public Health
Ann Arbor, Michigan USA

Raul Murillo, M.P.H.
General Director
Instituto Nacional de Cancerología de Columbia
Bogotá, Colombia

Nasheen Naidoo, M.B.B.Ch., M.P.H.
Senior Scientist
Health Promotion Research and Development Unit
Medical Research Council of South Africa
Cape Town, South Africa

Twalib Ngoma, M.D.
Executive Director
Ocean Road Cancer Institute
Dar es Salaam, Tanzania

Kola Okuyemi, M.D., M.P.H.
Professor
Director, Medical School Program in Health Disparities Research
Family Medicine and Community Health
University of Minnesota
Minneapolis, Minnesota USA

Olufunmilayo Olopade, M.D., F.A.C.P.
Professor of Medicine and Human Genetics
Director, Cancer Risk Clinic
The University of Chicago Medicine
Chicago, Illinois USA

Oluwafemi Oluwole, M.Sc.
Global Health Initiative
University of Chicago
Chicago, Illinois USA

Song-Yi Park, Ph.D.
Assistant Specialist
Cancer Epidemiology Program
University of Hawaii Cancer Center
Honolulu, Hawaii USA

Youlin Qiao, M.D.
Director, Department of Cancer Epidemiology
Cancer Institute of the Chinese Academy of Medical Sciences
Peking Union Medical College
Beijing, People's Republic of China

Priscilla Reddy, Ph.D.
Unit Director
Health Promotion Research and Development Unit
Medical Research Council of South Africa
Tygerberg, Cape Town
South Africa

Kenneth Resnicow, Ph.D.
Professor
Department of Health Behavior & Health Education
University of Michigan School of Public Health
Ann Arbor, Michigan USA

Karina Braga Ribeiro, Ph.D.
Adjunct Professor
Department of Social Medicine
Faculdade de Ciências Médicas da Santa Casa de São Paulo
Director
Division of Epidemiology
Fundação Oncocentro de São Paulo
São Paulo, Brazil

Rengaswamy Sankaranarayanan, M.D.
Head, Early Detection & Prevention Section
Head, Screening Group
International Agency for Research on Cancer
World Health Organization
Lyon, France

David Schottenfeld, M.D., M.S.
John G. Searle Professor Emeritus of Epidemiology
Professor Emeritus of Internal Medicine
University of Michigan School of Public Health and Medical School
Ann Arbor, Michigan USA

Ronel Sewpaul, M.Sc.
Scientist
Health Promotion Research and Development Unit
Medical Research Council of South Africa
Tygerberg, Cape Town
South Africa

Hongbing Shen, M.D., Ph.D.
Professor of Epidemiology
Department of Epidemiology & Biostatistics
School of Public Health
Nanjing Medical University
Nanjing, Jiangsu Province
China

Amr S. Soliman, M.D., Ph.D.
Professor and Chair of Epidemiology
Director of Cancer Epidemiology Education in Special Populations Program
University of Nebraska Medical Center
College of Public Health
Omaha, Nebraska USA

Somanathan Thara, M.D.
Additional Professor of Pathology
Division of Cytopathology
Regional Cancer Centre
Trivandrum, India

David B. Thomas, M.D., Dr.P.H.
Senior International Research Advisor, Breast Health Global Initiative
Member, Division of Public Health Sciences
Fred Hutchinson Cancer Research Center
Professor, Public Health Sciences
University of Washington
Seattle, Washington USA

Yonglan Zheng, Ph.D.
Department of Medicine
Center for Clinical Cancer Genetics and Global Health
University of Chicago
Chicago, Illinois USA