Cancer Biotherapy
An Introductory Guide
Edited by Annie Young, Lewis Rowett, and David Kerr
Table of Contents
Introduction, David Kerr, Lewis Rowett & Annie Young
1. An introduction to the cell biology of cancer, Lewis Rowett & Annie Young
2. An introduction to the immune system and cancer, Rachel Midgley
3. The clinical development of biologic therapies, David Kerr
4. Kinase inhibitors, Stefan Sleijfer, Kees Nooter & Jaap Verwejj
5. The RAS pathway - a target for anticancer therapy, Monica M Mita & Eric K Rowinsky
6. The development of cell cycle active agents for cancer therapy, Manish A Shah, Archie Tse & Gary K Schwartz
7. Therapeutic monoclonal antibodies, Peter Borchmann & Andreas Engert
8. Antibody Directed Enzyme Prodrug Therapy (ADEPT), Surinder K Sharma, Kenneth D Bagshawe & Richard H J Begent
9. Cytokines, Carla M L van Herpen & Cornelius J A Punt
10. Inhibitors of invasion and angiogenesis, Dirk Laurent
11. Proteins, peptides and DNA vaccines for cancer, Aniruddha Choudhury & Håkan Mellstedt
12. Cell based immunotherapy, Neil Steven
13. Gene therapy for cancer - approaches and ethical considerations, Deborah Beirne & Leonard Seymour
14. Individualising cancer therapy, Wan-Teck Lim & Howard L McLeod
Glossary
