1. The Early Days of Paleogenomics, Connecting Molecules to the Planet, Steven A. Benner
2. Ancestral Sequence Reconstruction as a Tool to Understand Natural History and Guide Synthetic Biology: Realizing and Extending the Vision of Zuckerkandl and Pauling, Eric A. Gaucher
3. Linking Sequence to Function in Drug Design with Ancestral Sequence Reconstruction, Janos T. Kodra, Marie Skovgaard, Dennis Madsen, and David A. Liberles
4. Probabilistic Models and Their Impact on the Accuracy of Reconstructed Ancestral Sequences, Tal Pupko, Adi Doron-Faigenboim, David A. Liberles, and Gina M. Cannarozzi
5. Probabilistic Ancestral Sequences Based on the Markovian Model of Evolution- Algorithms and Applications, Gina M. Cannarozzi, Adrian Schneider, and Gaston H. Gonnet
6. Estimating the History of Mutations on a Phylogeny, Jonathan P. Bollback, Paul P. Gardner, and Rasmus Nielsen
7. Coarse Projections of the Protein-Mutational Fitness Landscape, F. Nicholas Braun
8. Dealing with Uncertainty in Ancestral Sequence Reconstruction: Sampling from the Posterior Distribution, David D. Pollock and Belinda S. W. Chang
9. Evolutionary Properties of Sequences and Ancestral State Reconstruction, Lesley J. Collins and Peter J. Lockhart
10. Reconstructing the Ancestral Eukaryote- Lessons from the Past, Mary J. O'Connell and James O. McInerney
11. Using Ancestral Sequence Inference to Determine the Trend of Functional Divergence After Gene Duplication, Xun Gu, Ying Zheng, Yong Huang, and Dongping Xu
12. Reconstruction of Ancestral Proteomes, Toni Gabaldon and Martijn A. Huynen
13. Computational Reconstruction of Ancestral Genomic Regions from Evolutionarily Conserved Gene Clusters, Etienne G. J. Danchin, Eric A. Gaucher, and Pierre Pontarotti
14. Experimental Resurrection of Ancient Biomolecules: Gene Synthesis, Heterologous Protein Expression, and Functional Assays, Eric A. Gaucher
15. Dealing with Model Uncertainty in Reconstructing Ancestral Proteins in the Laboratory: Examples from Ancestral Visual Pigments and GFP-like Proteins, Belinda S. W. Chang, Mikhail V. Matz, Steven F. Field, Johannes Müller, and Ilke van Hazel
16. Unraveling the Evolution of Complexity by Resurrecting Ancient Genes, Joseph W. Thornton and Jamie T. Bridgham
17. A Thermophilic Last Universal Ancestor Inferred from its Estimated Amino Acid Composition, Dawn J. Brooks and Eric A. Gaucher
18. The Resurrection of Ribonucleases from Mammals. From Ecology to Medicine, Slim O. Sassi and Steven A. Benner
19. Evolution of Specificity and Diversity, Denis C. Shields, Kate Johnston, Iain M. Wallace, and Richard J. Edwards