Amyotrophic Lateral Sclerosis

Hiroshi Mitsumoto, David A. Chad, and Erik P. Pioro

F. A. Davis Co.

Contemporary Neurology Series

Reviews the newest modes of neuroimaging as used to diagnose ALS and to investigate the disease process
Clearly explains the relationship between electrotoxicity and free radical injury to foster a better understanding of the cell death process
Comprehensively covers recent clinical trials with a thorough discussion on their potential problems and issues
Provides a multidisciplinary approach to patient care and outlines alternative treatment options, including unconventional therapies and the pros and cons of ventilators
Includes a thoughful discussion of end-of-life issues and advice on how patients and their families can handle the financial stresses imposed by ALS

Amyotrophic Lateral Sclerosis

Hiroshi Mitsumoto, David A. Chad, and Erik P. Pioro

F. A. Davis Co.

Description

Amyotrophic Lateral Sclerosis presents the most comprehensive, clinically-focused information on ALS (Lou Gehrig's Disease) in print. The three authors, widely known for their work in this area, provide cohesive and balanced coverage of this syndrome, including the history, clinical features, pathology and pathogenesis, treatment and management of ALS. To facilitate understanding, each chapter is enhanced by comprehensive tables and figures, as well as detailed chapter summaries.

Amyotrophic Lateral Sclerosis

Hiroshi Mitsumoto, David A. Chad, and Erik P. Pioro

F. A. Davis Co.

Contemporary Neurology Series

Part One: Introduciton to ALS
1:History, Terminology, and Classification of ALS
2:Epidemiology
3:Functional Neuroanatomy of the Motor System
Part Two: Clinical Features of ALS
4:Clinical Features: Signs and Symptoms
5:Electrodiagnosis
6:The Differential Diagnosis of ALS
7:Diagnostic Investigation for ALS
8:Neuroimaging
9:Course and Prognosis
10:Familial ALS
Part Three: Pathology and Pathogenesis
11:Neuropathology
12:Excitotoxicity and Oxidative Damage in ALS pathogenesis
13:The Immune Hypothesis
14:Hypotheses for Viral and Other Transmissible Agents in ALS
15:Neurotrophic Factors for Motor Neurons
16:Other Hypotheses of ALS
17:Animal Models of ALS
Part Four: Treatment and Management
18:Comprehensive Care
19:Symptomatic Treatment
20:Treatment Trials
21:Physical Rehabilitation
22:Pulmonary Function and Respiratory Failure
23:Speech Therapy and Communication Management
24:Nutritional Management
25:Psychological Management
26:Medical Economics, Legality and Medical Ethics

Amyotrophic Lateral Sclerosis

Hiroshi Mitsumoto, David A. Chad, and Erik P. Pioro

F. A. Davis Co.

Contemporary Neurology Series

Author Information

Hiroshi Mitsumoto, Head, Neuromuscular Disease Section; Professor, Department of Neurology and Neurosciences, Cleveland Clinic Foundation, Ohio, David A. Chad, Professor of Neurology and Pathology, University of Massachusetts Medical Center, and Erik P. Pioro, Departments of Neurology and Neurosciences, Cleveland Clinic Foundation, Ohio