Section 1. Preventive Medicine

1. Preventing Diabetes: The Diabetes Prevention Program

2. Dietary Approaches to Stop Hypertension (DASH)

3. Aspirin for the Primary Prevention of Cardiovascular Disease: The Physicians' Health Study and the Women's Health Study

4. Postmenopausal Hormone Therapy: The Women's Health Initiative

5. The Cochrane Review of Screening Mammography

6. The European Randomized Study of Screening for Prostate Cancer

7. Screening for Lung Cancer with Low-Dose Computed Tomography vs. Chest Radiography: The National Lung Screening Trial (NLST)

Section 2. Endocrinology

8. Treating Elevated Blood Sugar Levels in Patients with Type 2 Diabetes: the United Kingdom Prospective Diabetes Study (UKPDS)

9. Intensive versus conservative blood sugar control for patients with type 2 diabetes: the ACCORD trial

10. Intensive vs. Conventional Glycemic Control in Type 1 Diabetes Mellitus (DCCT)

11. Intensive vs. Conservative Blood Pressure Control in Patients with Type 2 Diabetes

Section 3. Hematology and Oncology

12. Choice of Anticoagulant for Prevention of Recurrent Venous Thromboembolism in Patients with Cancer

13. Vena Caval Filters in the Prevention of Pulmonary Embolism in Patients with Proximal Deep-Vein Thrombosis

14. Phase I Study of Imatinib (STI571) in Patients with Chronic Myelogenous Leukemia

Section 4. Musculoskeletal Diseases

15. Magnetic Resonance Imaging for Low Back Pain

16. Early therapy for rheumatoid arthritis: The TICORA Study

Section 5. Nephrology

17. Revascularization vs. Medical Therapy for Renal Artery Stenosis

18. Correcting Anemia in Chronic Kidney Disease: The CHOIR Study

19. Early versus Late Initiation of Dialysis: The IDEAL Trial

Section 6. Gastroenterology

20. Use of IV Albumin in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis

21. Early use of transjugular intrahepatic portosystemic shunt (TIPS) in patients with cirrhosis and variceal bleeding

Section 7. Infectious Diseases

22. Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department

23. Antibiotic Therapy in Exacerbations of Chronic Obstructive Pulmonary Disease

24. Early versus Delayed Antiretroviral Therapy for Patients with HIV: The NA-ACCORD Study

Section 8. Cardiology

25. Statins in Healthy Patients with an Elevated C-Reactive Protein: The JUPITER Trial

26. The Scandinavian Simvastatin Survival Study (4S)

27. Choosing Fist-Line Therapy for Hypertension: The ALLHAT Trial

28. Rate Control versus Rhythm Control for Atrial Fibrillation: The AFFIRM Trial

29. Initial Treatment of Stable Coronary Artery Disease: The COURAGE Trial

30. Early Invasive vs. Conservative Management for Unstable Angina or Non-ST-Elevation Myocardial Infarction: The RITA 3 Trial

31. MADIT II: Prophylactic Defibrillator Implantation in Patients with Low Ejection Fraction Following Myocardial Infarction

32. Captopril in Patients with Left Ventricular Dysfunction after Myocardial Infarction: The SAVE Trial

33. Spironolactone in Advanced Heart Failure: The RALES Trial

34. The African American Heart Failure Trial (A-HeFT)

35. Intraaortic Balloon Support for Myocardial Infarction with Cardiogenic Shock (IABP-SHOCK II)

Section 9. Pulmonary and Critical Care Medicine

36. Intensive versus Conventional Glucose Control in Critically Ill Patients

37. Red Cell Transfusion in Critically Ill Patients: The TRICC Trial

38. Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease

39. Low Tidal Volume Ventilation in Acute Respiratory Distress Syndrome/Acute Lung Injury

40. Comparison of routine vs. on-demand chest radiographs in mechanically-ventilated adults in the intensive care unit

41. Early Goal-Directed Therapy in Sepsis

42. Dopamine vs. norepinephrine in the treatment of shock

43. Daily Interruption of Sedative Infusions in Critically Ill Patients Undergoing Mechanical Ventilation

44. A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation

Section 10. Geriatrics and Palliative Care

45. Behavioral versus Pharmacological Treatment for Insomnia in the Elderly

46. Treatment of Hypertension in the Elderly

47. Use of feeding tubes in patients with dementia

48. Early Palliative Care in Non-Small-Cell Lung Cancer

Section 11. Mental Health

49. Initial Treatment of Depression

50. Symptom-Triggered vs. Fixed Dose Therapy for Alcohol Withdrawal