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Cover

Advanced Genetic Analysis

Genes, Genomes, and Networks in Eukaryotes

Philip Meneely

Publication Date - March 2009

ISBN: 9780199219827

576 pages
Paperback
7-3/4 x 10-3/4 inches

In Stock

Retail Price to Students: $89.95

A student-friendly text that explores the latest genetic applications and developments that will help us better understand biological systems.

Description

How can we explore gene expression in time and space? How do we know what role a particular gene has? How do some genes control the expression of others? How do genes interact to form gene networks?

Advanced Genetic Analysis probes fascinating questions such as these by asking "How can the principles of genetics be used as analytical tools to solve biological problems?"

With its unique integration of genetics and molecular biology, Advanced Genetic Analysis provides a broad survey of how our understanding of key genetic phenomena can be used to understand biological systems. Opening with a brief overview of key genetic principles and model organisms, the books goes on to explore the use of gene mutations and the analysis of gene expression and activity, before considering the interactions of genes during suppression and epistasis, and how we study gene networks.

Drawing on the latest experimental tools, including microarrays, RNAi, and bioinformatics approaches, Advanced Genetic Analysis provides a state-of-the-art review of the field, but in a truly student-friendly manner. It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research without losing clarity of explanation and insight.

We are in an age where, despite knowing so much about biological systems, we are just beginning to realize how much more there is still to understand. Advanced Genetic Analysis is the ideal guide to how we can use the awesome power of molecular genetics to further our understanding.

Features

  • Uses established principles of genetics as methods to analyze larger problems in biology, so beginning where most genetics books leave off.
  • Illustrates the concept of key analytical tools with carefully selected examples from a range of model organisms, and encourages the reader to look beyond the examples to see how these tools apply to a wide range of biological problems.
  • Text boxes and extended case studies take coverage to a new level, allowing the reader to really get to grips with how we use genetic tools to understand biological systems.
  • The latest, most powerful tools are covered for the first time in a textbook, giving insights into the exploration of gene networks and gene interactions.
  • Full colour art complements the lively, engaging text to help the reader grasp the concepts being discussed.
  • The Online Resource Centre features additional materials for both instructors and students, adding to the value of the text as a teaching and learning tool.

About the Author(s)

Philip Meneely is Professor of Biology in the Department of Biology at Haverford College, PA, where he teaches genetics, molecular biology and bioinformatics alongside research exploring the genes involved in meiosis.

Table of Contents

    Unit 1 Genes and Genomes
    1. Introduction
    2. Model organisms
    Unit 2 Mutations
    3. Finding mutants
    4. Classifying mutants
    5. Cloning genes
    6. Reverse genetics
    7. Genome-wide screens
    Unit 3. Gene Activity
    8. Gene expression
    9. Gene activity
    Unit 4. Gene Interactions
    10. Suppression
    11. Epistasis
    12. Networks