Spessard and Miessler's Organometallic Chemistry, originally published by Prentice Hall in 1997, is widely acknowledged as the most appropriate text for undergraduates and beginning graduate students taking this course. It is a highly readable and approachable text that starts with the basic inorganic chemistry needed to understand this advanced topic. Spessard and Miessler place a strong emphasis on structure and bonding in the first several chapters, which lay the foundation for later discussion of reaction types and applications. In addition to being pitched at the right level for undergraduate students, Spessard and Miessler present outstanding explanations of important core topics such as molecular orbitals and bonding and support these discussions with detailed illustrations and praised end of chapter problems.
The second edition has been significantly revised and updated to include advancements over the last ten years in NMR, IR spectroscopy, nanotechnology and physical methods. The authors have significantly updated discussions of catalysis, carbene complexes, metathesis and polymerization reactions, especially including an expanded discussion of Schrock and Grubbs metal carbene catalysts. There are numerous applications of organotransition metal-catalyzed reactions covered in the second edition of this textbook. The Grubbs Cycle demonstrates just one of the most famous examples of how organometallic chemistry has greatly influenced the field of catalysis. Furthermore, there is a substantially-revised treatment of the applications of organometallic chemistry to organic synthesis. An entire chapter is devoted to an extensive discussion of asymmetric hydrogenation and oxidation methodology as well as a greatly revised treatment of Tsuji-Trost allylation, the Heck reaction, and palladium-catalyzed cross-coupling reactions. The latter topic includes discussion of the Stille, Suzuki, Sonogashira, and Negishi cross-couplings, reactions that have had a profound impact on the synthesis of anti-tumor compounds and other potent pharmaceuticals.
In addition, the authors have included more molecular model illustrations, and introduced more modern examples and medical/medicinal applications across the text. Students have the opportunity to test their knowledge of important concepts, since the number of in-chapter exercises has increased by 23%, while there are now 81% more end-of-chapter problems than the previous edition. Many end of chapter problems are referenced to the original literature.
The second edition of Spessard and Miessler presents the fundamentals of organometallic chemistry to undergraduate and graduate students through the presentation of seminal experiments, analysis of real data, and the inclusion of the most comprehensive problem sets available.
For a detailed list of what's new to this edition appears, click here.